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Q9XYP3 (IF6_TRYCR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Eukaryotic translation initiation factor 6

Short name=eIF-6
OrganismTrypanosoma cruzi
Taxonomic identifier5693 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

Protein attributes

Sequence length114 AA.
Sequence statusFragment.
Protein existenceInferred from homology

General annotation (Comments)

Function

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis By similarity.

Subunit structure

Monomer. Associates with the 60S ribosomal subunit By similarity.

Subcellular location

Cytoplasm By similarity. Nucleusnucleolus By similarity. Note: Shuttles between cytoplasm and nucleus/nucleolus By similarity.

Sequence similarities

Belongs to the eIF-6 family.

Ontologies

Keywords
   Biological processProtein biosynthesis
Ribosome biogenesis
   Cellular componentCytoplasm
Nucleus
   Molecular functionInitiation factor
Gene Ontology (GO)
   Biological_processmature ribosome assembly

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionribosome binding

Inferred from electronic annotation. Source: InterPro

translation initiation factor activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 114›114Eukaryotic translation initiation factor 6
PRO_0000153738

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q9XYP3 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 63671F07F6C532B3

FASTA11412,083
        10         20         30         40         50         60 
GTTFRTSIAE NALVGSYAVV NNKGCMVHPK TPAQDMDEIA SLLQVPVVAG TINRGNAAIG 

        70         80         90        100        110 
SGLVVNDWAA FCGLNTTATE ITVVERIFQL RRDLGGGRAN LLQQLRDTLV DELA 

« Hide

References

[1]"T. cruzi SZ5 locus DNA."
Lorenzi H., Catalani M., Levin M.J.
Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Tulahuen.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF117890 Genomic DNA. Translation: AAD24769.1.

3D structure databases

ProteinModelPortalQ9XYP3.
SMRQ9XYP3. Positions 3-90.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR002769. eIF6.
[Graphical view]
PANTHERPTHR10784. PTHR10784. 1 hit.
PfamPF01912. eIF-6. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameIF6_TRYCR
AccessionPrimary (citable) accession number: Q9XYP3
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: February 19, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Translation initiation factors

List of translation initiation factor entries