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Q9XYP3

- IF6_TRYCR

UniProt

Q9XYP3 - IF6_TRYCR

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Protein

Eukaryotic translation initiation factor 6

Gene
N/A
Organism
Trypanosoma cruzi
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis By similarity.By similarity

GO - Molecular functioni

  1. ribosome binding Source: InterPro
  2. translation initiation factor activity Source: UniProtKB-KW

GO - Biological processi

  1. mature ribosome assembly Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis, Ribosome biogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 6
Short name:
eIF-6
OrganismiTrypanosoma cruzi
Taxonomic identifieri5693 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

Subcellular locationi

Cytoplasm By similarity. Nucleusnucleolus By similarity
Note: Shuttles between cytoplasm and nucleus/nucleolus.By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 114›114Eukaryotic translation initiation factor 6PRO_0000153738Add
BLAST

Interactioni

Subunit structurei

Monomer. Associates with the 60S ribosomal subunit By similarity.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9XYP3.
SMRiQ9XYP3. Positions 3-90.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the eIF-6 family.Curated

Family and domain databases

InterProiIPR002769. eIF6.
[Graphical view]
PANTHERiPTHR10784. PTHR10784. 1 hit.
PfamiPF01912. eIF-6. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9XYP3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GTTFRTSIAE NALVGSYAVV NNKGCMVHPK TPAQDMDEIA SLLQVPVVAG
60 70 80 90 100
TINRGNAAIG SGLVVNDWAA FCGLNTTATE ITVVERIFQL RRDLGGGRAN
110
LLQQLRDTLV DELA
Length:114
Mass (Da):12,083
Last modified:November 1, 1999 - v1
Checksum:i63671F07F6C532B3
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF117890 Genomic DNA. Translation: AAD24769.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF117890 Genomic DNA. Translation: AAD24769.1 .

3D structure databases

ProteinModelPortali Q9XYP3.
SMRi Q9XYP3. Positions 3-90.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR002769. eIF6.
[Graphical view ]
PANTHERi PTHR10784. PTHR10784. 1 hit.
Pfami PF01912. eIF-6. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "T. cruzi SZ5 locus DNA."
    Lorenzi H., Catalani M., Levin M.J.
    Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: Tulahuen.

Entry informationi

Entry nameiIF6_TRYCR
AccessioniPrimary (citable) accession number: Q9XYP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3