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Q9XYP3

- IF6_TRYCR

UniProt

Q9XYP3 - IF6_TRYCR

Protein

Eukaryotic translation initiation factor 6

Gene
N/A
Organism
Trypanosoma cruzi
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis By similarity.By similarity

    GO - Molecular functioni

    1. ribosome binding Source: InterPro
    2. translation initiation factor activity Source: UniProtKB-KW

    GO - Biological processi

    1. mature ribosome assembly Source: InterPro

    Keywords - Molecular functioni

    Initiation factor

    Keywords - Biological processi

    Protein biosynthesis, Ribosome biogenesis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Eukaryotic translation initiation factor 6
    Short name:
    eIF-6
    OrganismiTrypanosoma cruzi
    Taxonomic identifieri5693 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaSchizotrypanum

    Subcellular locationi

    Cytoplasm By similarity. Nucleusnucleolus By similarity
    Note: Shuttles between cytoplasm and nucleus/nucleolus.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. nucleolus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 114›114Eukaryotic translation initiation factor 6PRO_0000153738Add
    BLAST

    Interactioni

    Subunit structurei

    Monomer. Associates with the 60S ribosomal subunit By similarity.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9XYP3.
    SMRiQ9XYP3. Positions 3-90.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the eIF-6 family.Curated

    Family and domain databases

    InterProiIPR002769. eIF6.
    [Graphical view]
    PANTHERiPTHR10784. PTHR10784. 1 hit.
    PfamiPF01912. eIF-6. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9XYP3-1 [UniParc]FASTAAdd to Basket

    « Hide

    GTTFRTSIAE NALVGSYAVV NNKGCMVHPK TPAQDMDEIA SLLQVPVVAG    50
    TINRGNAAIG SGLVVNDWAA FCGLNTTATE ITVVERIFQL RRDLGGGRAN 100
    LLQQLRDTLV DELA 114
    Length:114
    Mass (Da):12,083
    Last modified:November 1, 1999 - v1
    Checksum:i63671F07F6C532B3
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF117890 Genomic DNA. Translation: AAD24769.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF117890 Genomic DNA. Translation: AAD24769.1 .

    3D structure databases

    ProteinModelPortali Q9XYP3.
    SMRi Q9XYP3. Positions 3-90.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR002769. eIF6.
    [Graphical view ]
    PANTHERi PTHR10784. PTHR10784. 1 hit.
    Pfami PF01912. eIF-6. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "T. cruzi SZ5 locus DNA."
      Lorenzi H., Catalani M., Levin M.J.
      Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Tulahuen.

    Entry informationi

    Entry nameiIF6_TRYCR
    AccessioniPrimary (citable) accession number: Q9XYP3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. Translation initiation factors
      List of translation initiation factor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3