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Protein

Putative H/ACA ribonucleoprotein complex subunit 2-like protein

Gene

Y48A6B.3

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, RNA-binding
Biological processRibosome biogenesis, rRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Putative H/ACA ribonucleoprotein complex subunit 2-like protein
Gene namesi
ORF Names:Y48A6B.3
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome III

Organism-specific databases

WormBaseiY48A6B.3; CE19186; WBGene00012964.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001367711 – 163Putative H/ACA ribonucleoprotein complex subunit 2-like proteinAdd BLAST163

Proteomic databases

EPDiQ9XXD4.
PaxDbiQ9XXD4.
PeptideAtlasiQ9XXD4.
PRIDEiQ9XXD4.

Expressioni

Gene expression databases

BgeeiWBGene00012964.

Interactioni

Subunit structurei

Component of the small nucleolar ribonucleoprotein particle containing H/ACA-type snoRNAs (H/ACA snoRNPs).

Protein-protein interaction databases

STRINGi6239.Y48A6B.3.1.

Structurei

3D structure databases

ProteinModelPortaliQ9XXD4.
SMRiQ9XXD4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3167. Eukaryota.
COG1358. LUCA.
GeneTreeiENSGT00550000074939.
HOGENOMiHOG000055227.
InParanoidiQ9XXD4.
KOiK11129.
OMAiNIPYCYT.
OrthoDBiEOG091G0VZK.
PhylomeDBiQ9XXD4.

Family and domain databases

Gene3Di3.30.1330.30. 1 hit.
InterProiView protein in InterPro
IPR002415. H/ACA_rnp_Nhp2_euk.
IPR029064. L30e-like.
IPR004038. Ribosomal_L7Ae/L30e/S12e/Gad45.
IPR018492. Ribosomal_L7Ae/L8/Nhp2.
IPR004037. Ribosomal_L7Ae_CS.
PfamiView protein in Pfam
PF01248. Ribosomal_L7Ae. 1 hit.
PRINTSiPR00881. L7ARS6FAMILY.
PR00883. NUCLEARHMG.
SUPFAMiSSF55315. SSF55315. 1 hit.
PROSITEiView protein in PROSITE
PS01082. RIBOSOMAL_L7AE. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XXD4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKRNLDETM NESTVSEANG DATAPTTEKD EYQALCELVN PIAQPLANRK
60 70 80 90 100
LAKKVYKLIK KASAGDKTLR EGIKDVQKEL RRNEKGICIL AGNVSPIDVY
110 120 130 140 150
SHIPGICEEK EIPYVYIPSR EQLGLAVGHR RPSILIFVKP SGDFKELYDE
160
VAEALRHLTV EAA
Length:163
Mass (Da):18,091
Last modified:November 1, 1999 - v1
Checksum:iD1440685F584651A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL023844 Genomic DNA. Translation: CAA19527.1.
PIRiT26980.
RefSeqiNP_499415.1. NM_067014.5.
UniGeneiCel.9762.

Genome annotation databases

EnsemblMetazoaiY48A6B.3; Y48A6B.3; WBGene00012964.
GeneIDi176531.
KEGGicel:CELE_Y48A6B.3.
UCSCiY48A6B.3.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiNHP2_CAEEL
AccessioniPrimary (citable) accession number: Q9XXD4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 5, 2005
Last sequence update: November 1, 1999
Last modified: June 7, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families