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Protein
Submitted name:

DNA helicase

Gene

mcm-3

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotationSAAS annotation, HelicaseImported, Hydrolase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-CEL-69052. Switching of origins to a post-replicative state.
R-CEL-69300. Removal of licensing factors from origins.

Names & Taxonomyi

Protein namesi
Submitted name:
DNA helicaseImported
Gene namesi
Name:mcm-3Imported
ORF Names:C25D7.6Imported, CELE_C25D7.6Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiC25D7.6; CE08392; WBGene00003155; mcm-3.

Subcellular locationi

GO - Cellular componenti

  • condensed chromosome Source: WormBase
  • MCM complex Source: WormBase
  • nucleus Source: WormBase
  • pronucleus Source: WormBase

PTM / Processingi

Proteomic databases

EPDiQ9XVR7.
PaxDbiQ9XVR7.
PeptideAtlasiQ9XVR7.

Expressioni

Gene expression databases

BgeeiWBGene00003155.

Interactioni

Protein-protein interaction databases

DIPiDIP-27417N.
IntActiQ9XVR7. 1 interactor.
MINTiMINT-1080205.
STRINGi6239.C25D7.6.2.

Structurei

3D structure databases

ProteinModelPortaliQ9XVR7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini298 – 504MCMInterPro annotationAdd BLAST207

Sequence similaritiesi

Belongs to the MCM family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0479. Eukaryota.
COG1241. LUCA.
GeneTreeiENSGT00890000139442.
HOGENOMiHOG000224126.
InParanoidiQ9XVR7.
KOiK02541.
OMAiNEKRANR.
OrthoDBiEOG091G02B0.
PhylomeDBiQ9XVR7.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR031327. MCM.
IPR008046. Mcm3.
IPR018525. MCM_CS.
IPR001208. MCM_dom.
IPR033762. MCM_OB.
IPR012340. NA-bd_OB-fold.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00493. MCM. 1 hit.
PF17207. MCM_OB. 1 hit.
PRINTSiPR01657. MCMFAMILY.
PR01659. MCMPROTEIN3.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SM00350. MCM. 1 hit.
SUPFAMiSSF50249. SSF50249. 1 hit.
SSF52540. SSF52540. 2 hits.
PROSITEiView protein in PROSITE
PS00847. MCM_1. 1 hit.
PS50051. MCM_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XVR7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDGQADGMFI DRAEDARKQE ITEQYLNFLD NQADTFHYRQ KIVKMMNDGE
60 70 80 90 100
SRLVMNLDEI REILPERAEG LLTQSVLEMN CLQSALQMAI NRSDVQAVVK
110 120 130 140 150
TGFHVGFEGT FGERHVNPRT LKSSYLGNLV CCEGIVTKCS TVRQKLLTSV
160 170 180 190 200
HYCPATNKVL EKKFADFTML DTAVTNNNYP TEDENKNPLE TEFGHSVYKD
210 220 230 240 250
HQTFTIQELP ESAPAGQLPR AVDCVADLDL ADRVKPGDRV RIIGVFRVLP
260 270 280 290 300
NKQNGVSSGS FRSIIIINHI QMLSKEVIPN FEPQDVKDVR KISKSRNPFE
310 320 330 340 350
LLARSLAPSI CGHEETKKAL LCLLLGGMEK ILNNGSRLRG DINVLLIGDP
360 370 380 390 400
SVAKSQLLRY VLRMAPRAIT TTGRGSSGVG LTAAVTTDPD SGERRLEAGA
410 420 430 440 450
MVLADRGVVC IDEFDKMSDI DRTAIHEVME QGRVTISKAG IHAKLNARCS
460 470 480 490 500
VLAAANPVYG RYNPFKSPME NIGMQDSLLS RFDLIFVLLD EHDADKDANV
510 520 530 540 550
AEHVLKLHTY RTQGEADGTV LPMGGGVETI STINMETKKA SSSIYEENTQ
560 570 580 590 600
WAGIQDTKIL TMDFMRKYIH LARSVQPKLT DEATEYISEV YADIRSFDIT
610 620 630 640 650
KTDQERTMPV TARQLETLIR LSTAIAKARF SKKVEREDTE KAYNLLHFAC
660 670 680 690 700
FKEKPKARQE YEKKKRAPRI DGDDDEDQSD NEDMATSEEP QSSSVPTAAT
710 720 730 740 750
PRRGVRRRAE DDDSQDSMMD TTIGESQPTA KKARTGPAAI GVDRYKELRK
760 770 780 790 800
YVRKAFDDIG STDDMVELQI ITDSVQTQAG SHKFTEDELK AGYEQLENDN
810
AAMIAEDKIT LI
Length:812
Mass (Da):90,689
Last modified:November 1, 1999 - v1
Checksum:iA22BDB19CA4EE994
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA. Translation: CAB02770.1.
PIRiT19446.
RefSeqiNP_506706.1. NM_074305.5.
UniGeneiCel.17485.

Genome annotation databases

EnsemblMetazoaiC25D7.6; C25D7.6; WBGene00003155.
GeneIDi180010.
KEGGicel:CELE_C25D7.6.
UCSCiC25D7.6. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiQ9XVR7_CAEEL
AccessioniPrimary (citable) accession number: Q9XVR7
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported