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Protein

60S ribosomal protein L8

Gene

rpl-8

Organism
Caenorhabditis elegans
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding

Enzyme and pathway databases

ReactomeiR-CEL-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-CEL-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-CEL-72689. Formation of a pool of free 40S subunits.
R-CEL-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-CEL-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L8
Gene namesi
Name:rpl-8
Synonyms:rpl-2
ORF Names:B0250.1
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome V

Organism-specific databases

WormBaseiB0250.1; CE18478; WBGene00004413; rpl-2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001297511 – 26060S ribosomal protein L8Add BLAST260

Proteomic databases

EPDiQ9XVF7.
PaxDbiQ9XVF7.
PeptideAtlasiQ9XVF7.
PRIDEiQ9XVF7.

Expressioni

Gene expression databases

BgeeiWBGene00004413.

Interactioni

Protein-protein interaction databases

BioGridi45300. 5 interactors.
DIPiDIP-24785N.
IntActiQ9XVF7. 2 interactors.
MINTiMINT-1062067.
STRINGi6239.B0250.1.2.

Structurei

3D structure databases

ProteinModelPortaliQ9XVF7.
SMRiQ9XVF7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2309. Eukaryota.
COG0090. LUCA.
GeneTreeiENSGT00390000009907.
HOGENOMiHOG000232983.
InParanoidiQ9XVF7.
KOiK02938.
OMAiHGYIKGV.
OrthoDBiEOG091G0K1G.
PhylomeDBiQ9XVF7.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
4.10.950.10. 1 hit.
InterProiView protein in InterPro
IPR012340. NA-bd_OB-fold.
IPR022666. Rbsml_prot_L2_RNA-bd_dom.
IPR014722. Rib_L2_dom2.
IPR002171. Ribosomal_L2.
IPR022669. Ribosomal_L2_C.
IPR022671. Ribosomal_L2_CS.
IPR014726. Ribosomal_L2_dom3.
IPR008991. Translation_prot_SH3-like_sf.
PANTHERiPTHR13691. PTHR13691. 1 hit.
PfamiView protein in Pfam
PF00181. Ribosomal_L2. 1 hit.
PF03947. Ribosomal_L2_C. 1 hit.
PIRSFiPIRSF002158. Ribosomal_L2. 1 hit.
SMARTiView protein in SMART
SM01383. Ribosomal_L2. 1 hit.
SM01382. Ribosomal_L2_C. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
SSF50249. SSF50249. 1 hit.
PROSITEiView protein in PROSITE
PS00467. RIBOSOMAL_L2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XVF7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRRIRIQRK GAGGIFKSHN KHRKGASKLR PLDYAERHGY IKGLVKDIIH
60 70 80 90 100
DPGRGAPLAI IAFRDPYKYK TVKTTVVAAE GMHTGQFIHC GAKAQIQIGN
110 120 130 140 150
IVPVGTLPEG TTICNVENKS GDRGVIARAS GNYATVIAHN PDTKKTRIRL
160 170 180 190 200
PSGAKKVVQS VNRAMIGLVA GGGRTDKPLL KAGRSYHKYK AKRNSWPRVR
210 220 230 240 250
GVAMNPVEHP HGGGNHQHIG HPSTVRRDAS AGKKVGLIAA RRTGRIRGGK
260
PVKFTKEENV
Length:260
Mass (Da):28,204
Last modified:November 1, 1999 - v1
Checksum:iEA8EA20430A79213
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z81453 Genomic DNA. Translation: CAB03792.1.
PIRiT18676.
RefSeqiNP_507940.1. NM_075539.5.
UniGeneiCel.9069.

Genome annotation databases

EnsemblMetazoaiB0250.1; B0250.1; WBGene00004413.
GeneIDi180343.
KEGGicel:CELE_B0250.1.
UCSCiB0250.1.1. c. elegans.

Similar proteinsi

Entry informationi

Entry nameiRL8_CAEEL
AccessioniPrimary (citable) accession number: Q9XVF7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: November 1, 1999
Last modified: November 22, 2017
This is version 119 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families