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Q9XTL2 (Q9XTL2_DROME) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Jak pathway signal transduction adaptor molecule EMBL AAD34350.1
Submitted name:
LD02639p EMBL AAO74697.1
Submitted name:
Signal transducing adaptor molecule EMBL AAF53027.1
Submitted name:
Signal transducting adaptor protein EMBL AAD37503.1
Gene names
Name:Stam FlyBase FBgn0027363 EMBL AAD34350.1
Synonyms:STAM EMBL AAD37503.1
ORF Names:CG6521 FlyBase FBgn0027363, Dmel_CG6521 EMBL AAF53027.1
OrganismDrosophila melanogaster (Fruit fly)
Taxonomic identifier7227 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Endopterygota › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora

Protein attributes

Sequence length689 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338

Contains 1 VHS domain. SAAS SAAS018205

Sequences

Sequence LengthMass (Da)Tools
Q9XTL2 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 9304EB11A0C24373

FASTA68974,634
        10         20         30         40         50         60 
MGIFGQSSPF DADVEKATSE TNTNDNWSLI LDVCDKVTTN PRLAKDCLKA VMRRMGHTDP 

        70         80         90        100        110        120 
HVVMQAITLL DALSNNCGKP LHLEVASRDF ETEFRRLLAK AQPKVSLKMR QVLKNWAEND 

       130        140        150        160        170        180 
YKNDRELDLI PALYAKLRQE GYDFKNLGDK TSKTVAEKAA ALPKDPNVVS SQQEEDDIAK 

       190        200        210        220        230        240 
AIELSLKENK GSPKTGSVAS TGTASAYPSL YPSFAGTGSS APSAEASSAP APEPRKVRAL 

       250        260        270        280        290        300 
YDFEAAEENE LTFFAGEIIH VLDDSDPNWW KGYNQRGEGL FPSNFVTADL SVDPERLDIN 

       310        320        330        340        350        360 
QQHKSAAAAG QRELDSAAAL QQKTEAAAAA AAAQPVEIDE SKIDRLLHLL HEANPEDPSQ 

       370        380        390        400        410        420 
DSDEMLQLEQ EVHQMGPLID AELERVDRKH AQLTQLSSDL VDAINLYHTL MRDDRAAAGH 

       430        440        450        460        470        480 
FAAAAGGFMP GLAGFPGAAL YGAPGYPAAG GFPPAQNYPG MHSMPYGPVP NPPTSAPSQA 

       490        500        510        520        530        540 
PGAPGGYLGQ PQGQVPLPYQ NGHAAQMNSL PAHLTQPTGT APMPQPIYTQ PTPVTTQQQQ 

       550        560        570        580        590        600 
QPLPQHPQQP PQQQGQQPPQ HPQNSYHIDP QSQYAQVPPA VTQIQQPQQP PAPHAYMSPQ 

       610        620        630        640        650        660 
HQQAPPPQGY QPGPNLYGPN GSPAVVNPQS YMSPQQQQQQ HPPPHDQFSQ LHQQMAAMSM 

       670        680 
AGGPPVGAPG YHMQNDAVKN NIPIYQQQR

« Hide

References

« Hide 'large scale' references
[1]"The genome sequence of Drosophila melanogaster."
Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., Sutton G.G., Wortman J.R., Yandell M.D. expand/collapse author list , Zhang Q., Chen L.X., Brandon R.C., Rogers Y.H., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Gabor G.L., Abril J.F., Agbayani A., An H.J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., Harris N.L., Harvey D., Heiman T.J., Hernandez J.R., Houck J., Hostin D., Houston K.A., Howland T.J., Wei M.H., Ibegwam C., Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D., Kraft C., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A., Li J., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., Reinert K., Remington K., Saunders R.D., Scheeler F., Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T., Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.Y., Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., WoodageT, Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.
Science 287:2185-2195(2000) [PubMed: 10731132] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Berkeley.
[2]"The Drosophila STAM gene homolog is in a tight gene cluster, and its expression correlates to that of the adjacent gene ial."
Mesilaty-Gross S., Reich A., Motro B., Wides R.
Gene 231:173-186(1999) [PubMed: 10231582] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[3]"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review."
Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., Bettencourt B.R., Celniker S.E., de Grey A.D.N.J. expand/collapse author list , Drysdale R.A., Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.
Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002) [PubMed: 12537572] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley.
[4]Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., Miranda A. expand/collapse author list , Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., Celniker S.
Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Berkeley EMBL AAO74697.1.
[5]"Cloning, mapping, and expression of ial, a novel Drosophila member of the Ipl1/aurora cell and centrosome cycle control kinase family."
Reich A., Yanai A., Mesilaty-Gross S., Chen-Moses A., Wides R., Motro B.
Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF121359 mRNA. Translation: AAD34350.1.
AF121361 Genomic DNA. Translation: AAD37503.1.
AE014134 Genomic DNA. Translation: AAF53027.1.
BT006014 mRNA. Translation: AAO74697.1.
RefSeqNP_477448.1. NM_058100.3.
UniGeneDm.401.

3D structure databases

HSSPHSSP built from PDB template 1OEB based on UniProtKB O89100.
ProteinModelPortalQ9XTL2.
SMRQ9XTL2. Positions 1-151, 233-289, 338-413.
ModBaseSearch...

Protein-protein interaction databases

IntActQ9XTL2. 25 interactions.
MINTMINT-967691.
STRINGQ9XTL2.

Proteomic databases

PRIDEQ9XTL2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaFBtr0080143; FBpp0079732; FBgn0027363.
GeneID34505.
KEGGdme:Dmel_CG6521.
NMPDRfig|7227.3.peg.1920.
UCSCCG6521-RA. d. melanogaster.

Organism-specific databases

CTD8027.
FlyBaseFBgn0027363. Stam.

Phylogenomic databases

eggNOGinNOG05872.
GeneTreeEMGT00050000000076.
InParanoidQ9XTL2.
OMAAINLYHT.
OrthoDBEOG4DNCMP.
PhylomeDBQ9XTL2.

Gene expression databases

ArrayExpressQ9XTL2.
BgeeQ9XTL2.

Family and domain databases

InterProIPR008942. ENTH_VHS.
IPR001452. SH3_domain.
IPR003903. Ubiquitin-int_motif.
IPR002014. VHS.
IPR018205. VHS_subgr.
[Graphical view]
Gene3DG3DSA:1.25.40.90. ENTH_VHS. 1 hit.
KOK04705.
PfamPF00018. SH3_1. 1 hit.
PF00790. VHS. 1 hit.
[Graphical view]
PRINTSPR00452. SH3DOMAIN.
SMARTSM00326. SH3. 1 hit.
SM00726. UIM. 1 hit.
SM00288. VHS. 1 hit.
[Graphical view]
SUPFAMSSF48464. ENTH_VHS. 1 hit.
SSF50044. SH3. 1 hit.
PROSITEPS50002. SH3. 1 hit.
PS50330. UIM. 1 hit.
PS50179. VHS. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio788828.

Entry information

Entry nameQ9XTL2_DROME
AccessionPrimary (citable) accession number: Q9XTL2
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: January 25, 2012
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info