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Protein
Submitted name:

CTLA-4 protein

Gene

CTLA4

Organism
Felis catus (Cat) (Felis silvestris catus)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
CTLA-4 proteinImported
Submitted name:
Costimulatory molecule B7 receptor CD152Imported
Submitted name:
Cytotoxic T-lymphocyte associated protein 4Imported
Submitted name:
Cytotoxic T-lymphocyte-associated 4Imported
Gene namesi
Name:CTLA4Imported
Synonyms:CD152Imported, CTLA-4Imported
OrganismiFelis catus (Cat) (Felis silvestris catus)
Taxonomic identifieri9685 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraFeliformiaFelidaeFelinaeFelis
Proteomesi
  • UP000011712 Componenti: Chromosome C1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei162 – 186HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSFCAG00000014272.

Interactioni

Protein-protein interaction databases

STRINGi9685.ENSFCAP00000013243.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini43 – 152IGInterPro annotationAdd BLAST110
Domaini53 – 131IGvInterPro annotationAdd BLAST79

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IJ05. Eukaryota.
ENOG410YUQR. LUCA.
GeneTreeiENSGT00530000063873.
HOVERGENiHBG057978.
KOiK06538.
OMAiFSKGMHV.
OrthoDBiEOG091G0IGY.
TreeFamiTF335679.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR008096. CTLA4.
IPR036179. Ig-like_dom_sf.
IPR013783. Ig-like_fold.
IPR003599. Ig_sub.
IPR013106. Ig_V-set.
PANTHERiPTHR11494:SF8. PTHR11494:SF8. 1 hit.
PfamiView protein in Pfam
PF07686. V-set. 1 hit.
PRINTSiPR01720. CTLANTIGEN4.
SMARTiView protein in SMART
SM00409. IG. 1 hit.
SM00406. IGv. 1 hit.
SUPFAMiSSF48726. SSF48726. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XTA1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MACFGFRRHG AQLDLASRTW PCTALFSLLF IPVFSKGMHV AQPAVVLASS
60 70 80 90 100
RGVASFVCEY GSSGNAAEVR VTVLRQTGSQ MTEVCAATYT VENELAFLDD
110 120 130 140 150
STCTGISSGN KVNLTIQGLR AMDTGLYICK VELMYPPPYY AGMGNGTQIY
160 170 180 190 200
VIDPEPCPDS DFLLWILAAV SSGLFFYSFL ITAVSLSKML KKRSPLTTGV
210 220
YVKMPPTEPE CEKQFQPYFI PIN
Length:223
Mass (Da):24,379
Last modified:November 1, 1999 - v1
Checksum:i125C2DF76CEE6E7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AANG02153407 Genomic DNA. No translation available.
AF170725 mRNA. Translation: AAD50988.1.
AF154844 mRNA. Translation: AAG43372.1.
AB029395 mRNA. Translation: BAA82273.1.
RefSeqiNP_001009236.1. NM_001009236.1.
XP_019691508.1. XM_019835949.1.
XP_019691509.1. XM_019835950.1.

Genome annotation databases

EnsembliENSFCAT00000014276; ENSFCAP00000013243; ENSFCAG00000014272.
GeneIDi493743.
KEGGifca:493743.

Similar proteinsi

Entry informationi

Entry nameiQ9XTA1_FELCA
AccessioniPrimary (citable) accession number: Q9XTA1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: November 22, 2017
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported