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Protein

60S ribosomal protein L27

Gene

RPL27

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Component of the large ribosomal subunit (By similarity). Required for proper rRNA processing and maturation of 28S and 5.8S rRNAs (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L27
Gene namesi
Name:RPL27
ORF Names:B173
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis
Proteomesi
  • UP000002254 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001260751 – 13660S ribosomal protein L27Add BLAST136

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei27N6-acetyllysineBy similarity1
Modified residuei93N6-acetyllysineBy similarity1

Keywords - PTMi

Acetylation

Proteomic databases

PaxDbiQ9XSU7.

Interactioni

Subunit structurei

Component of the large ribosomal subunit. Interacts with RRP1B.By similarity

Protein-protein interaction databases

STRINGi9615.ENSCAFP00000021561.

Structurei

3D structure databases

ProteinModelPortaliQ9XSU7.
SMRiQ9XSU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 40KOWAdd BLAST36

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3418. Eukaryota.
COG2163. LUCA.
HOGENOMiHOG000210138.
HOVERGENiHBG050005.
InParanoidiQ9XSU7.
KOiK02901.

Family and domain databases

Gene3Di2.30.30.30. 1 hit.
InterProiView protein in InterPro
IPR005824. KOW.
IPR014722. Rib_L2_dom2.
IPR001141. Ribosomal_L27e.
IPR018262. Ribosomal_L27e_CS.
IPR008991. Translation_prot_SH3-like_sf.
PANTHERiPTHR10497. PTHR10497. 1 hit.
PfamiView protein in Pfam
PF00467. KOW. 1 hit.
PF01777. Ribosomal_L27e. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD009396. Ribosomal_L27e. 1 hit.
SMARTiView protein in SMART
SM00739. KOW. 1 hit.
SUPFAMiSSF50104. SSF50104. 1 hit.
PROSITEiView protein in PROSITE
PS01107. RIBOSOMAL_L27E. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XSU7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKFMKPGKV VLVLAGRYSG RKAVIVKNID DGTSDRPYSH ALVAGIDRYP
60 70 80 90 100
RKVTAAMGKK KIAKRSKIKS FVKVYNYNHL MPTRYSVDIP LDKTVVNKDV
110 120 130
FRDPALKRKA RREAKVKFEE KYKTGKNKWF FQKLRF
Length:136
Mass (Da):15,770
Last modified:January 23, 2007 - v3
Checksum:i5404151495029A2D
GO

Sequence cautioni

The sequence CAB46818 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ388516 mRNA. Translation: CAB46818.1. Different initiation.
RefSeqiNP_001003102.2. NM_001003102.2.
UniGeneiCfa.28035.

Genome annotation databases

GeneIDi403688.
KEGGicfa:403688.

Similar proteinsi

Entry informationi

Entry nameiRL27_CANLF
AccessioniPrimary (citable) accession number: Q9XSU7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 88 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families