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Protein
Submitted name:

C-type Fas antigen

Gene

FAS

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
C-type Fas antigenImported
Submitted name:
Fas antigenImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:FASImported
OrganismiOryctolagus cuniculus (Rabbit)
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 18

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei162 – 17918HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 320300Sequence analysisPRO_5007217097Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000023210.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini69 – 11244TNFR-CysInterPro annotationAdd
BLAST
Domaini113 – 15038TNFR-CysInterPro annotationAdd
BLAST
Domaini213 – 29785DeathInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J23A. Eukaryota.
ENOG4112ADB. LUCA.
GeneTreeiENSGT00730000111280.
HOGENOMiHOG000139681.
HOVERGENiHBG004091.
OMAiCTTCEHG.
TreeFamiTF333916.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
[Graphical view]
PANTHERiPTHR23097:SF114. PTHR23097:SF114. 1 hit.
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01680. TNFACTORR6.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 3 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XS29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGIWVLLPL ILTCIAGSLS TSINDCKIKN ETQYSTGYLS GNFCCQLCPP
60 70 80 90 100
GTKKKADCTS NEGKPDCEPC QEGEEYTDKS HFSSKCRRCS LCDGEHGLEV
110 120 130 140 150
ETDCTTIQNT KCRCKSNFFC NALKCEHCDP CTMCEHGIIE ECTQTSNTKC
160 170 180 190 200
KEKGSTTGSK HHFLWLLCIL LLIPIVLGLR RYKKHRDGKH GYDKSTALIP
210 220 230 240 250
EGVPMNFSDV DISKYIPTIA EEMKINEVKE FVRKNGVNEA KIDEIKNDNI
260 270 280 290 300
QDTAEQKVQL LRNWHQLHGK KDAYNTLIKG LRKANLCALA EKIQDIVQKD
310 320
ITSDHDNLDI RDEKERQSLA
Length:320
Mass (Da):36,102
Last modified:November 1, 1999 - v1
Checksum:iDA235E243220FFB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02036412 Genomic DNA. No translation available.
AAGW02036413 Genomic DNA. No translation available.
AB021296 mRNA. Translation: BAA78428.1.
AB021299 mRNA. Translation: BAA78431.1.
RefSeqiXP_008268124.1. XM_008269902.1.
UniGeneiOcu.2354.

Genome annotation databases

EnsembliENSOCUT00000026155; ENSOCUP00000023210; ENSOCUG00000008202.
GeneIDi100008609.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02036412 Genomic DNA. No translation available.
AAGW02036413 Genomic DNA. No translation available.
AB021296 mRNA. Translation: BAA78428.1.
AB021299 mRNA. Translation: BAA78431.1.
RefSeqiXP_008268124.1. XM_008269902.1.
UniGeneiOcu.2354.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000023210.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSOCUT00000026155; ENSOCUP00000023210; ENSOCUG00000008202.
GeneIDi100008609.

Organism-specific databases

CTDi355.

Phylogenomic databases

eggNOGiENOG410J23A. Eukaryota.
ENOG4112ADB. LUCA.
GeneTreeiENSGT00730000111280.
HOGENOMiHOG000139681.
HOVERGENiHBG004091.
OMAiCTTCEHG.
TreeFamiTF333916.

Family and domain databases

Gene3Di1.10.533.10. 1 hit.
InterProiIPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
[Graphical view]
PANTHERiPTHR23097:SF114. PTHR23097:SF114. 1 hit.
PfamiPF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
[Graphical view]
PRINTSiPR01680. TNFACTORR6.
SMARTiSM00005. DEATH. 1 hit.
SM00208. TNFR. 3 hits.
[Graphical view]
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiPS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Splicing and allelic variation in the rabbit Fas antigen gene."
    Isono T., Tanbe Y., Nagano Y., Seto A.
    Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "A high-resolution map of human evolutionary constraint using 29 mammals."
    Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.
    , Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.
    Nature 478:476-482(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ThorbeckeImported and Thorbecke inbredImported.
  3. Ensembl
    Submitted (SEP-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: ThorbeckeImported.

Entry informationi

Entry nameiQ9XS29_RABIT
AccessioniPrimary (citable) accession number: Q9XS29
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: May 11, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.