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Protein
Submitted name:

C-type Fas antigen

Gene

FAS

Organism
Oryctolagus cuniculus (Rabbit)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
C-type Fas antigenImported
Submitted name:
Fas antigenImported
Submitted name:
Fas cell surface death receptorImported
Gene namesi
Name:FASImported
OrganismiOryctolagus cuniculus (Rabbit)
Taxonomic identifieri9986 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresLagomorphaLeporidaeOryctolagus
Proteomesi
  • UP000001811 Componenti: Chromosome 18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei162 – 179HelicalSequence analysisAdd BLAST18

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501084850721 – 320Sequence analysisAdd BLAST300

Expressioni

Gene expression databases

BgeeiENSOCUG00000008202.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9986.ENSOCUP00000023210.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini69 – 112TNFR-CysInterPro annotationAdd BLAST44
Repeati69 – 112TNFR-CysPROSITE-ProRule annotationAdd BLAST44
Domaini113 – 150TNFR-CysInterPro annotationAdd BLAST38
Repeati113 – 150TNFR-CysPROSITE-ProRule annotationAdd BLAST38
Domaini213 – 297DeathInterPro annotationAdd BLAST85

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410J23A. Eukaryota.
ENOG4112ADB. LUCA.
GeneTreeiENSGT00730000111280.
HOGENOMiHOG000139681.
HOVERGENiHBG004091.
OMAiCTTCEHG.
OrthoDBiEOG091G0DU6.
TreeFamiTF333916.

Family and domain databases

CDDicd08316. Death_FAS_TNFRSF6. 1 hit.
cd10579. TNFRSF6. 1 hit.
InterProiView protein in InterPro
IPR011029. DEATH-like_dom.
IPR000488. Death_domain.
IPR008063. Fas_rcpt.
IPR001368. TNFR/NGFR_Cys_rich_reg.
IPR033998. TNFRSF6_death.
IPR033999. TNFRSF6_N.
PANTHERiPTHR23097:SF158. PTHR23097:SF158. 1 hit.
PfamiView protein in Pfam
PF00531. Death. 1 hit.
PF00020. TNFR_c6. 1 hit.
PRINTSiPR01680. TNFACTORR6.
SMARTiView protein in SMART
SM00005. DEATH. 1 hit.
SM00208. TNFR. 3 hits.
SUPFAMiSSF47986. SSF47986. 1 hit.
PROSITEiView protein in PROSITE
PS50017. DEATH_DOMAIN. 1 hit.
PS50050. TNFR_NGFR_2. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9XS29-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGIWVLLPL ILTCIAGSLS TSINDCKIKN ETQYSTGYLS GNFCCQLCPP
60 70 80 90 100
GTKKKADCTS NEGKPDCEPC QEGEEYTDKS HFSSKCRRCS LCDGEHGLEV
110 120 130 140 150
ETDCTTIQNT KCRCKSNFFC NALKCEHCDP CTMCEHGIIE ECTQTSNTKC
160 170 180 190 200
KEKGSTTGSK HHFLWLLCIL LLIPIVLGLR RYKKHRDGKH GYDKSTALIP
210 220 230 240 250
EGVPMNFSDV DISKYIPTIA EEMKINEVKE FVRKNGVNEA KIDEIKNDNI
260 270 280 290 300
QDTAEQKVQL LRNWHQLHGK KDAYNTLIKG LRKANLCALA EKIQDIVQKD
310 320
ITSDHDNLDI RDEKERQSLA
Length:320
Mass (Da):36,102
Last modified:November 1, 1999 - v1
Checksum:iDA235E243220FFB3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAGW02036412 Genomic DNA. No translation available.
AAGW02036413 Genomic DNA. No translation available.
AB021296 mRNA. Translation: BAA78428.1.
AB021299 mRNA. Translation: BAA78431.1.
RefSeqiXP_008268124.1. XM_008269902.2.
UniGeneiOcu.2354.

Genome annotation databases

EnsembliENSOCUT00000026155; ENSOCUP00000023210; ENSOCUG00000008202.
GeneIDi100008609.

Similar proteinsi

Entry informationi

Entry nameiQ9XS29_RABIT
AccessioniPrimary (citable) accession number: Q9XS29
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Keywords - Technical termi

Complete proteome, Reference proteomeImported