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Protein
Submitted name:

Classical MHC class I molecule, alpha-chain

Gene

Orla-UAA

Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Classical MHC class I molecule, alpha-chainImported
Submitted name:
Mhc class I AImported
Gene namesi
Name:Orla-UAAImported
OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
Taxonomic identifieri8090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei304 – 32724HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 356337Sequence analysisPRO_5005944613Add
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini202 – 28786Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the MHC class I family.UniRule annotation
Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOGENOMiHOG000296917.
HOVERGENiHBG016709.
KOiK06751.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XR30-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIQLILCFL GLSFHGAAAV SHSLKYFYTA SSQVPNFPEF VAVGLVDDAQ
60 70 80 90 100
IDYYDSDIRM DIPKQDWMKE AMDEQYWERE TGNKLGSQQT FKANIEIAKQ
110 120 130 140 150
RFNQTGGVHV YQWMYGCEWD DETGEINSFH QYGYDGEDFI ALDLKTESWI
160 170 180 190 200
AAKQQAFITK QKWDNDNAKK AQDKNYFTQI CPEWLKKYVN YGSSSLMRKV
210 220 230 240 250
LPSVSLLQKS SSSAVSCHAT GFYPDRAELL WRRDGEEIHE GVEKGQILPN
260 270 280 290 300
NDGTFQMSVD LQPPSGEDMQ RYECVFQLSG VKEDVITKLE KAKIRTNEGS
310 320 330 340 350
SSQMLIIIGV LAAVIAVILS VSAFILYKKK NAKRPPSPVD NKEIQQQMLQ

PENPSA
Length:356
Mass (Da):40,468
Last modified:November 1, 1999 - v1
Checksum:i53C2E81C063A2C93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026977 mRNA. Translation: BAA77557.1.
AB183488 Genomic DNA. Translation: BAD93265.1.
RefSeqiNP_001098573.1. NM_001105103.1.
UniGeneiOla.4188.

Genome annotation databases

GeneIDi100125825.
KEGGiola:100125825.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB026977 mRNA. Translation: BAA77557.1.
AB183488 Genomic DNA. Translation: BAD93265.1.
RefSeqiNP_001098573.1. NM_001105103.1.
UniGeneiOla.4188.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi100125825.
KEGGiola:100125825.

Organism-specific databases

CTDi100125825.

Phylogenomic databases

HOGENOMiHOG000296917.
HOVERGENiHBG016709.
KOiK06751.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.30.500.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003597. Ig_C1-set.
IPR011161. MHC_I-like_Ag-recog.
IPR011162. MHC_I/II-like_Ag-recog.
IPR027648. MHC_I_a.
IPR001039. MHC_I_a_a1/a2.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00129. MHC_I. 1 hit.
[Graphical view]
PRINTSiPR01638. MHCCLASSI.
SMARTiSM00407. IGc1. 1 hit.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 1 hit.
SSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Mhc class I A genes from medaka fish."
    Naruse K.
    Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HNIImported.
  2. "Unprecedented intraspecific diversity of the MHC class I region of a teleost medaka, Oryzias latipes."
    Tsukamoto K., Hayashi S., Matsuo M.Y., Nonaka M.I., Kondo M., Shima A., Asakawa S., Shimizu N., Nonaka M.
    Immunogenetics 57:420-431(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HNIImported.
  3. "Evolutionary analysis of two classical MHC class I loci of the medaka fish, Oryzias latipes: haplotype-specific genomic diversity, locus-specific polymorphisms, and interlocus homogenization."
    Nonaka M.I., Nonaka M.
    Immunogenetics 62:319-332(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HNIImported.

Entry informationi

Entry nameiQ9XR30_ORYLA
AccessioniPrimary (citable) accession number: Q9XR30
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: February 17, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.