Q9XI80 (FUT6_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Fucosyltransferase 6
Short name=AtFUT6
EC=2.4.1.-

Gene names

Name:	FUT6
Ordered Locus Names:	At1g14080
ORF Names:	F7A19.16, F16A14.28

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	537 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be involved in cell wall biosynthesis. May act as a fucosyltransferase.
Pathway	Protein modification; protein glycosylation.
Subcellular location	Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein By similarity. Note: Membrane-bound form in trans cisternae of Golgi By similarity.
Tissue specificity	Expressed in roots and flowers. Ref.3
Sequence similarities	Belongs to the glycosyltransferase 37 family.
Sequence caution	The sequence AAF79408.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence AAO00849.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended. The sequence AAP68320.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell wall biogenesis Inferred from electronic annotation. Source: InterPro cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	Golgi cisterna membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	galactoside 2-alpha-L-fucosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 537	537	Fucosyltransferase 6		PRO_0000193915
Regions
	Topological domain	1 – 20	20	Cytoplasmic Potential
	Transmembrane	21 – 41	21	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	42 – 537	496	Lumenal Potential
Amino acid modifications
	Glycosylation	54	1	N-linked (GlcNAc...) Potential
	Glycosylation	231	1	N-linked (GlcNAc...) Potential
	Glycosylation	378	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9XI80 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 25DA4756D4394EA2	FASTA	537	61,191
	10 20 30 40 50 60 MYHIFQISSE VFRAFGLKMK ILLTLVFSGL LIWSVVLVSF SNDFNNQLLV ATSNVSRESE 70 80 90 100 110 120 TPRDRLIGGL LTADFDEGSC LSRYQQSLLY RKASPYKPSE YLVSKLRSYE KLHKRCGPGT 130 140 150 160 170 180 DAYKKATEIL GHDDENYASK SVGECRYIVW VAVYGLGNRI LTLASVFLYA LLTERVVLVD 190 200 210 220 230 240 QSKDISDLFC EPFPGTSWLL PLEFPLMKQI DGYNKGYSRC YGTMLNNQAI NSTLIPPHLY 250 260 270 280 290 300 LHILHDSRDN DKMFFCQKDQ SLVDKVPWLI VKANVYFVPS LWLNPTFQTE LMKLFPQKEA 310 320 330 340 350 360 VFHHLARYLF HPTNQVWGLI TRSYNAYLSR ADETLGIQIR VFSDRAGYFQ HVMDQVVACT 370 380 390 400 410 420 RRENLLPEPA AQEEPKVNIS RSQKLKAVLV TSLYPEYSET LKNMYWERPS STGEIIEVYQ 430 440 450 460 470 480 PSGERVQQTD KKLHDQKALA EMYLLSLTDK IVTSARSTFG YVAHSLGGLK PWLLYQPTGP 490 500 510 520 530 TAPDPPCIQS TSMDPCHLTP PSHGCEPEWG TNSGKVVPFV RHCEDRGNDG LKLFDEL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	"Empirical analysis of transcriptional activity in the Arabidopsis genome." Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G. , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R. Science 302:842-846(2003) [PubMed: 14593172] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 2-537. Strain: cv. Columbia.
[3]	"Characterization of a family of Arabidopsis genes related to xyloglucan fucosyltransferase1." Sarria R., Wagner T.A., O'Neill M.A., Faik A., Wilkerson C.G., Keegstra K., Raikhel N.V. Plant Physiol. 127:1595-1606(2001) [PubMed: 11743104] [Abstract] Cited for: IDENTIFICATION AS A PUTATIVE FUCOSYLTRANSFERASE, TISSUE SPECIFICITY.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007576 Genomic DNA. Translation: AAD39293.1. AC068197 Genomic DNA. Translation: AAF79408.1. Sequence problems. BT002489 mRNA. Translation: AAO00849.1. Different initiation. BT008881 mRNA. Translation: AAP68320.1. Different initiation.
IPI	IPI00537290.
PIR	B86274.
RefSeq	NP_172860.1. NM_101273.2.
UniGene	At.41992.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT37. Glycosyltransferase Family 37.
Proteomic databases
PRIDE	Q9XI80.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	837968.
GenomeReviews	Gene locus AT1G14080 in contig CT485782_GR.
KEGG	ath:AT1G14080.
Organism-specific databases
TAIR	At1g14080.
Phylogenomic databases
GeneTree	EPGT00050000010289.
HOGENOM	HBG319216.
InParanoid	Q9XI80.
PhylomeDB	Q9XI80.
Gene expression databases
Genevestigator	Q9XI80.
GermOnline	AT1G14080. Arabidopsis thaliana.
Family and domain databases
InterPro	IPR004938. XG_FTase. [Graphical view]
KO	K13681.
Pfam	PF03254. XG_FTase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FUT6_ARATH

Accession

Primary (citable) accession number: Q9XI80
Secondary accession number(s): Q8GUI5, Q9LMF2

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 69 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program