Q9XI78 (FUT8_ARATH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable fucosyltransferase 8
Short name=AtFUT8
EC=2.4.1.-

Gene names

Name:	FUT8
Ordered Locus Names:	At1g14100
ORF Names:	F7A19.18

Organism

Arabidopsis thaliana (Mouse-ear cress)

Taxonomic identifier

3702 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis

Protein attributes

Sequence length	516 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May be involved in cell wall biosynthesis. May act as a fucosyltransferase.
Pathway	Protein modification; protein glycosylation.
Subcellular location	Golgi apparatus › Golgi stack membrane; Single-pass type II membrane protein By similarity. Note: Membrane-bound form in trans cisternae of Golgi By similarity.
Tissue specificity	Expressed in leaves and stems. Ref.3
Sequence similarities	Belongs to the glycosyltransferase 37 family.
Sequence caution	The sequence AAD39294.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Golgi apparatus Membrane
Domain	Signal-anchor Transmembrane Transmembrane helix
Molecular function	Glycosyltransferase Transferase
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cell wall biogenesis Inferred from electronic annotation. Source: InterPro cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	Golgi cisterna membrane Inferred from electronic annotation. Source: UniProtKB-SubCell integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	galactoside 2-alpha-L-fucosyltransferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 516	516	Probable fucosyltransferase 8		PRO_0000193917
Regions
	Transmembrane	5 – 25	21	Helical; Signal-anchor for type II membrane protein; Potential
	Topological domain	26 – 516	491	Lumenal Potential
Amino acid modifications
	Glycosylation	35	1	N-linked (GlcNAc...) Potential
	Glycosylation	116	1	N-linked (GlcNAc...) Potential
	Glycosylation	211	1	N-linked (GlcNAc...) Potential
	Glycosylation	362	1	N-linked (GlcNAc...) Potential
	Glycosylation	463	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9XI78 [UniParc]. Last modified May 31, 2011. Version 2. Checksum: 72E2C96AC88EECDE	FASTA	516	59,286
	10 20 30 40 50 60 MKVVITVVTC LFLLSVMQLS FFNIFNYQLL DATTNGSKDS RKSKDKLLGG LLTADFDEDS 70 80 90 100 110 120 CLSRYESSLY RKPSPYKPSR YLVSKLRSYE MLHKRCGPGT EAYKKATEIL GHDDENHSTK 130 140 150 160 170 180 SVGECRYIVW IAVYGLGNRI LTLASLFLYA LLTDRIMLVD QRTDISDLFC EPFPGTSWLL 190 200 210 220 230 240 PLDFPLTDQL DSFNKESPRC YGTMLKNHAI NSTTTESIIP SYLCLYLIHD YDDYDKMFFC 250 260 270 280 290 300 ESDQILIRQV PWLVFNSNLY FIPSLWLIPS FQSELSKLFP QKETVFHHLA RYLFHPTNQV 310 320 330 340 350 360 WGMITRSYNG YLSRADERLG IQVRVFSKPA GYFQHVMDQI LACTQREKLL PEVFVLETQV 370 380 390 400 410 420 TNTSRSSKLK AVLVTSLYPE YSEILRQMYW KGPSSTGEII QIYQPSQEIY QQTDNKLHDQ 430 440 450 460 470 480 KALAEIYLLS LTDYIVTSDS STFGYVAQGL GGLKPWILYK PKNHTAPEPP CVRAVSMEPC 490 500 510 FLRAPLYGCQ AKKVNITPFV MYCEDRITGL KLVDSN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana." Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K. , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W. Nature 408:816-820(2000) [PubMed: 11130712] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Columbia.
[2]	The Arabidopsis Information Resource (TAIR) Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: cv. Columbia.
[3]	"Characterization of a family of Arabidopsis genes related to xyloglucan fucosyltransferase1." Sarria R., Wagner T.A., O'Neill M.A., Faik A., Wilkerson C.G., Keegstra K., Raikhel N.V. Plant Physiol. 127:1595-1606(2001) [PubMed: 11743104] [Abstract] Cited for: IDENTIFICATION AS A PUTATIVE FUCOSYLTRANSFERASE, TISSUE SPECIFICITY.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC007576 Genomic DNA. Translation: AAD39294.1. Different initiation. CP002684 Genomic DNA. Translation: AEE29106.1.
IPI	IPI00846552.
PIR	D86274.
RefSeq	NP_001077531.1. NM_001084062.1.
UniGene	At.72233.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GT37. Glycosyltransferase Family 37.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	AT1G14100.1; AT1G14100.1; AT1G14100.
GeneID	5007694.
GenomeReviews	Gene locus AT1G14100 in contig CT485782_GR.
KEGG	ath:AT1G14100.
Organism-specific databases
TAIR	At1g14100.
Phylogenomic databases
GeneTree	EPGT00050000010289.
HOGENOM	HBG319216.
Gene expression databases
ArrayExpress	Q9XI78.
Genevestigator	Q9XI78.
Family and domain databases
InterPro	IPR004938. XG_FTase. [Graphical view]
KO	K13681.
Pfam	PF03254. XG_FTase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FUT8_ARATH

Accession

Primary (citable) accession number: Q9XI78

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 5, 2002
Last sequence update:	May 31, 2011
Last modified:	November 16, 2011
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program