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Q9XGX1 (CHS7_SORBI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Chalcone synthase 7

EC=2.3.1.74
Alternative name(s):
Naringenin-chalcone synthase 7
Gene names
Name:CHS7
OrganismSorghum bicolor (Sorghum) (Sorghum vulgare)
Taxonomic identifier4558 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeSorghum

Protein attributes

Sequence length400 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activity

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathway

Secondary metabolite biosynthesis; flavonoid biosynthesis.

Sequence similarities

Belongs to the chalcone/stilbene synthases family.

Ontologies

Keywords
   Biological processFlavonoid biosynthesis
   Molecular functionAcyltransferase
Transferase
Gene Ontology (GO)
   Biological_processflavonoid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionnaringenin-chalcone synthase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 400400Chalcone synthase 7
PRO_0000216061

Sites

Active site1681 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9XGX1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 7A67C8D6ADA05CB9

FASTA40043,576
        10         20         30         40         50         60 
MAGATVTVEE VRKAQRATGP ATVLAIGTAT PANCVHQADY PDYYFRITKS EHMTDLKEKF 

        70         80         90        100        110        120 
KRMCDKSQIR KRYMHLTEEY LAENPNMCAY MAPSLDARQD IVVVEVPKLG KAAAQKAIKE 

       130        140        150        160        170        180 
WGQPKSKITH LVFCTTSGVD MPGADYQLTK MLGLRPSVNR LMMYQQGCFA GGTVLRVAKD 

       190        200        210        220        230        240 
LAENNRGARV LVVCSEITAV TFRGPSESHL DSMVGQALFG DGAAAVIVGA DPDKRVECPL 

       250        260        270        280        290        300 
FQLVSASQTI LPDSEGAIDG HLREVGLTFH LLKDVPGLIS KNIERSLEEA FKPLGITDYN 

       310        320        330        340        350        360 
SIFWVAHPGG PAILDQVEAK VGLKKERMRA TRHVLSEYGN MSSACVLFIL DEMRKRSAEE 

       370        380        390        400 
GQATTGEGFD WGVLFGFGPG LTVETVVLHS VPITIAAITA 

« Hide

References

[1]"Molecular cloning of chalcone synthase genes from sorghum."
Lo S.-C.C., Nicholson R.L.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: cv. BTx623.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF152554 Genomic DNA. Translation: AAD41879.1.
RefSeqXP_002450876.1. XM_002450831.1.
UniGeneSbi.20237.

3D structure databases

ProteinModelPortalQ9XGX1.
SMRQ9XGX1. Positions 7-393.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING4558.Sb05g020220.1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8064819.
KEGGsbi:SORBI_05g020220.

Organism-specific databases

GrameneQ9XGX1.

Phylogenomic databases

eggNOGCOG3424.
HOGENOMHOG000245460.
KOK00660.
OMAKRVECPL.

Enzyme and pathway databases

UniPathwayUPA00154.

Family and domain databases

Gene3D3.40.47.10. 2 hits.
InterProIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFPIRSF000451. PKS_III. 1 hit.
SUPFAMSSF53901. SSF53901. 2 hits.
PROSITEPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHS7_SORBI
AccessionPrimary (citable) accession number: Q9XGX1
Entry history
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: November 1, 1999
Last modified: May 14, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways