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Q9XGX1

- CHS7_SORBI

UniProt

Q9XGX1 - CHS7_SORBI

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Protein

Chalcone synthase 7

Gene

CHS7

Organism
Sorghum bicolor (Sorghum) (Sorghum vulgare)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei168 – 1681PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase 7 (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase 7
Gene namesi
Name:CHS7
OrganismiSorghum bicolor (Sorghum) (Sorghum vulgare)
Taxonomic identifieri4558 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogoneaeSorghum

Organism-specific databases

GrameneiQ9XGX1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 400400Chalcone synthase 7PRO_0000216061Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi4558.Sb05g020220.1.

Structurei

3D structure databases

ProteinModelPortaliQ9XGX1.
SMRiQ9XGX1. Positions 7-393.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Phylogenomic databases

eggNOGiCOG3424.
HOGENOMiHOG000245460.
KOiK00660.
OMAiKRVECPL.

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XGX1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGATVTVEE VRKAQRATGP ATVLAIGTAT PANCVHQADY PDYYFRITKS
60 70 80 90 100
EHMTDLKEKF KRMCDKSQIR KRYMHLTEEY LAENPNMCAY MAPSLDARQD
110 120 130 140 150
IVVVEVPKLG KAAAQKAIKE WGQPKSKITH LVFCTTSGVD MPGADYQLTK
160 170 180 190 200
MLGLRPSVNR LMMYQQGCFA GGTVLRVAKD LAENNRGARV LVVCSEITAV
210 220 230 240 250
TFRGPSESHL DSMVGQALFG DGAAAVIVGA DPDKRVECPL FQLVSASQTI
260 270 280 290 300
LPDSEGAIDG HLREVGLTFH LLKDVPGLIS KNIERSLEEA FKPLGITDYN
310 320 330 340 350
SIFWVAHPGG PAILDQVEAK VGLKKERMRA TRHVLSEYGN MSSACVLFIL
360 370 380 390 400
DEMRKRSAEE GQATTGEGFD WGVLFGFGPG LTVETVVLHS VPITIAAITA
Length:400
Mass (Da):43,576
Last modified:November 1, 1999 - v1
Checksum:i7A67C8D6ADA05CB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF152554 Genomic DNA. Translation: AAD41879.1.
RefSeqiXP_002450876.1. XM_002450831.1.
UniGeneiSbi.20237.

Genome annotation databases

GeneIDi8064819.
KEGGisbi:SORBI_05g020220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF152554 Genomic DNA. Translation: AAD41879.1 .
RefSeqi XP_002450876.1. XM_002450831.1.
UniGenei Sbi.20237.

3D structure databases

ProteinModelPortali Q9XGX1.
SMRi Q9XGX1. Positions 7-393.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 4558.Sb05g020220.1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 8064819.
KEGGi sbi:SORBI_05g020220.

Organism-specific databases

Gramenei Q9XGX1.

Phylogenomic databases

eggNOGi COG3424.
HOGENOMi HOG000245460.
KOi K00660.
OMAi KRVECPL.

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of chalcone synthase genes from sorghum."
    Lo S.-C.C., Nicholson R.L.
    Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. BTx623.

Entry informationi

Entry nameiCHS7_SORBI
AccessioniPrimary (citable) accession number: Q9XGX1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 8, 2000
Last sequence update: November 1, 1999
Last modified: October 1, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3