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Protein

Galactinol synthase 1

Gene

GOLS1

Organism
Ajuga reptans (Bugle)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Major galactinol synthase mainly involved in the biosynthesis of storage raffinose family oligosaccharides (RFOs) that function as osmoprotectants. May promote plant stress tolerance.1 Publication

Catalytic activityi

UDP-alpha-D-galactose + myo-inositol = UDP + O-alpha-D-galactosyl-(1->3)-1D-myo-inositol.1 Publication

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei104By similarity1
Metal bindingi120ManganeseBy similarity1
Metal bindingi122ManganeseBy similarity1
Metal bindingi257ManganeseBy similarity1

GO - Molecular functioni

  • inositol 3-alpha-galactosyltransferase activity Source: UniProtKB
  • metal ion binding Source: UniProtKB-KW

GO - Biological processi

  • carbohydrate storage Source: UniProtKB
  • cellular response to cold Source: UniProtKB
  • galactose metabolic process Source: UniProtKB-KW
  • metabolic process Source: UniProtKB
  • raffinose family oligosaccharide biosynthetic process Source: UniProtKB
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Galactose metabolism

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BRENDAi2.4.1.123. 222.

Protein family/group databases

CAZyiGT8. Glycosyltransferase Family 8.

Names & Taxonomyi

Protein namesi
Recommended name:
Galactinol synthase 1 (EC:2.4.1.123)
Short name:
ArGolS1
Short name:
GolS-1
Gene namesi
Name:GOLS1
OrganismiAjuga reptans (Bugle)
Taxonomic identifieri38596 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesLamiaceaeTeucrioideaeAjuga

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004186551 – 333Galactinol synthase 1Add BLAST333

Expressioni

Tissue specificityi

Expressed in source leaves, specifically in the mesophyll.1 Publication

Inductioni

By cold. Follows a circadian rhythm; accumulates mostly at midday during the light phase.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ9XGN4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
InterProiIPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF01501. Glyco_transf_8. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XGN4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPVVPVEAF RSAGKISALG AKKGYVTFLA GNGDYVKGVV GLAKGLRKVK
60 70 80 90 100
SAYPLVVAIL PDVPEEHREL LRSQGCIVKE IEPIYPPANQ IQFAMAYYVI
110 120 130 140 150
NYSKLRIWNF EEYSKMVYLD ADIQVYENID HLLDTPDGYF YAVMDCFCEK
160 170 180 190 200
TWSHSRQFSI GYCQQCPNKV TWPAQMGSPP PLYFNAGMFV FEPSKTTYQT
210 220 230 240 250
LLHTLRITPP TPFAEQDFLN MFFEPIYKPI PLVYNLVLAM LWRHPENVEL
260 270 280 290 300
EKVQVVHYCA AGSKPWRYTG QEANMDREDI KMLVKKWWDV YNDESLDFKA
310 320 330
EDSIAGEETF SMPSFIASLP EPAVSYIPAP SAA
Length:333
Mass (Da):37,882
Last modified:November 1, 1999 - v1
Checksum:iB3D575F9084DFF6B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ237693 mRNA. Translation: CAB51533.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ237693 mRNA. Translation: CAB51533.1.

3D structure databases

ProteinModelPortaliQ9XGN4.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGT8. Glycosyltransferase Family 8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

BRENDAi2.4.1.123. 222.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
InterProiIPR002495. Glyco_trans_8.
IPR029044. Nucleotide-diphossugar_trans.
[Graphical view]
PfamiPF01501. Glyco_transf_8. 1 hit.
[Graphical view]
SUPFAMiSSF53448. SSF53448. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGOLS1_AJURE
AccessioniPrimary (citable) accession number: Q9XGN4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2012
Last sequence update: November 1, 1999
Last modified: November 11, 2015
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.