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Q9XGH7 (PP2A_TOBAC) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP2A catalytic subunit

EC=3.1.3.16
OrganismNicotiana tabacum (Common tobacco)
Taxonomic identifier4097 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 1 iron ion per subunit By similarity.

Binds 1 manganese ion per subunit By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-2A subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandIron
Manganese
Metal-binding
   Molecular functionHydrolase
Protein phosphatase
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoprotein phosphatase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 312312Serine/threonine-protein phosphatase PP2A catalytic subunit
PRO_0000058865

Sites

Active site1211Proton donor By similarity
Metal binding601Iron By similarity
Metal binding621Iron By similarity
Metal binding881Iron By similarity
Metal binding881Manganese By similarity
Metal binding1201Manganese By similarity
Metal binding1701Manganese By similarity
Metal binding2441Manganese By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9XGH7 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: B24F1ABEC2793315

FASTA31235,639
        10         20         30         40         50         60 
MDPVPSSASH GNLDEQIAQL MQCKPLSEQE VRGLCEKAKE ILMEESNVQP VKSPVTICGD 

        70         80         90        100        110        120 
IHGQFHDLAE LFRIGGKCPD TNYLFMGDYV DRGYYSVETV TLLVALKVRY PQRITILRGN 

       130        140        150        160        170        180 
HESRQITQVY GFYDECLRKY GNANVWKTFT DLFDYFPLTA LVESEIFCLH GGLSPSIETL 

       190        200        210        220        230        240 
DNIRNFDRVQ EVPHEGAMCD LLWSDPDDRC GWGISPRGAG YTFGQDISEQ FNHTNNLKLI 

       250        260        270        280        290        300 
ARAHQLVMEG FNWAHDQKVV TIFSAPNYCY RCGNMASILE VDDSRERTFI QFEPAPRRGE 

       310 
PDVTRRTPDY FL 

« Hide

References

[1]"Molecular analysis of protein phosphatase 2A in tobacco."
Remus M., Stitt M., Zrenner R.
Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. SR1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ007496 mRNA. Translation: CAB46506.1.

3D structure databases

ProteinModelPortalQ9XGH7.
SMRQ9XGH7. Positions 13-312.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP2A_TOBAC
AccessionPrimary (citable) accession number: Q9XGH7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: April 16, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families