Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9XGH7

- PP2A_TOBAC

UniProt

Q9XGH7 - PP2A_TOBAC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Serine/threonine-protein phosphatase PP2A catalytic subunit

Gene
N/A
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi60 – 601Manganese 1By similarity
Metal bindingi62 – 621Manganese 1By similarity
Metal bindingi88 – 881Manganese 1By similarity
Metal bindingi88 – 881Manganese 2By similarity
Metal bindingi120 – 1201Manganese 2By similarity
Active sitei121 – 1211Proton donorBy similarity
Metal bindingi170 – 1701Manganese 2By similarity
Metal bindingi244 – 2441Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP2A catalytic subunit (EC:3.1.3.16)
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 312312Serine/threonine-protein phosphatase PP2A catalytic subunitPRO_0000058865Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9XGH7.
SMRiQ9XGH7. Positions 13-312.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-2A subfamily.Curated

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XGH7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDPVPSSASH GNLDEQIAQL MQCKPLSEQE VRGLCEKAKE ILMEESNVQP
60 70 80 90 100
VKSPVTICGD IHGQFHDLAE LFRIGGKCPD TNYLFMGDYV DRGYYSVETV
110 120 130 140 150
TLLVALKVRY PQRITILRGN HESRQITQVY GFYDECLRKY GNANVWKTFT
160 170 180 190 200
DLFDYFPLTA LVESEIFCLH GGLSPSIETL DNIRNFDRVQ EVPHEGAMCD
210 220 230 240 250
LLWSDPDDRC GWGISPRGAG YTFGQDISEQ FNHTNNLKLI ARAHQLVMEG
260 270 280 290 300
FNWAHDQKVV TIFSAPNYCY RCGNMASILE VDDSRERTFI QFEPAPRRGE
310
PDVTRRTPDY FL
Length:312
Mass (Da):35,639
Last modified:November 1, 1999 - v1
Checksum:iB24F1ABEC2793315
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ007496 mRNA. Translation: CAB46506.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ007496 mRNA. Translation: CAB46506.1 .

3D structure databases

ProteinModelPortali Q9XGH7.
SMRi Q9XGH7. Positions 13-312.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular analysis of protein phosphatase 2A in tobacco."
    Remus M., Stitt M., Zrenner R.
    Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. SR1.

Entry informationi

Entry nameiPP2A_TOBAC
AccessioniPrimary (citable) accession number: Q9XGH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3