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Protein

Serine/threonine-protein phosphatase PP2A catalytic subunit

Gene
N/A
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mn2+By similarityNote: Binds 2 manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi60Manganese 1By similarity1
Metal bindingi62Manganese 1By similarity1
Metal bindingi88Manganese 1By similarity1
Metal bindingi88Manganese 2By similarity1
Metal bindingi120Manganese 2By similarity1
Active sitei121Proton donorBy similarity1
Metal bindingi170Manganese 2By similarity1
Metal bindingi244Manganese 2By similarity1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP2A catalytic subunit (EC:3.1.3.16)
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana
Proteomesi
  • UP000084051 Componenti: Genome assembly

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000588651 – 312Serine/threonine-protein phosphatase PP2A catalytic subunitAdd BLAST312

Proteomic databases

PRIDEiQ9XGH7

Structurei

3D structure databases

ProteinModelPortaliQ9XGH7
SMRiQ9XGH7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family. PP-2A subfamily.Curated

Phylogenomic databases

KOiK04382

Family and domain databases

Gene3Di3.60.21.10, 1 hit
InterProiView protein in InterPro
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
IPR006186 Ser/Thr-sp_prot-phosphatase
PfamiView protein in Pfam
PF00149 Metallophos, 1 hit
PRINTSiPR00114 STPHPHTASE
SMARTiView protein in SMART
SM00156 PP2Ac, 1 hit
PROSITEiView protein in PROSITE
PS00125 SER_THR_PHOSPHATASE, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XGH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPVPSSASH GNLDEQIAQL MQCKPLSEQE VRGLCEKAKE ILMEESNVQP
60 70 80 90 100
VKSPVTICGD IHGQFHDLAE LFRIGGKCPD TNYLFMGDYV DRGYYSVETV
110 120 130 140 150
TLLVALKVRY PQRITILRGN HESRQITQVY GFYDECLRKY GNANVWKTFT
160 170 180 190 200
DLFDYFPLTA LVESEIFCLH GGLSPSIETL DNIRNFDRVQ EVPHEGAMCD
210 220 230 240 250
LLWSDPDDRC GWGISPRGAG YTFGQDISEQ FNHTNNLKLI ARAHQLVMEG
260 270 280 290 300
FNWAHDQKVV TIFSAPNYCY RCGNMASILE VDDSRERTFI QFEPAPRRGE
310
PDVTRRTPDY FL
Length:312
Mass (Da):35,639
Last modified:November 1, 1999 - v1
Checksum:iB24F1ABEC2793315
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ007496 mRNA Translation: CAB46506.1
RefSeqiNP_001312211.1, NM_001325282.1
XP_016462375.1, XM_016606889.1
UniGeneiNta.7128

Genome annotation databases

GeneIDi107779504
107785560
KEGGinta:107779504
nta:107785560

Similar proteinsi

Entry informationi

Entry nameiPP2A_TOBAC
AccessioniPrimary (citable) accession number: Q9XGH7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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