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Q9XGH7

- PP2A_TOBAC

UniProt

Q9XGH7 - PP2A_TOBAC

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Protein

Serine/threonine-protein phosphatase PP2A catalytic subunit

Gene
N/A
Organism
Nicotiana tabacum (Common tobacco)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 manganese ions per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi60 – 601Manganese 1 By similarity
Metal bindingi62 – 621Manganese 1 By similarity
Metal bindingi88 – 881Manganese 1 By similarity
Metal bindingi88 – 881Manganese 2 By similarity
Metal bindingi120 – 1201Manganese 2 By similarity
Active sitei121 – 1211Proton donor By similarity
Metal bindingi170 – 1701Manganese 2 By similarity
Metal bindingi244 – 2441Manganese 2 By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. phosphoprotein phosphatase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphatase PP2A catalytic subunit (EC:3.1.3.16)
OrganismiNicotiana tabacum (Common tobacco)
Taxonomic identifieri4097 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaeNicotianoideaeNicotianeaeNicotiana

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 312312Serine/threonine-protein phosphatase PP2A catalytic subunitPRO_0000058865Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9XGH7.
SMRiQ9XGH7. Positions 13-312.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.60.21.10. 1 hit.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 1 hit.
PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XGH7-1 [UniParc]FASTAAdd to Basket

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MDPVPSSASH GNLDEQIAQL MQCKPLSEQE VRGLCEKAKE ILMEESNVQP    50
VKSPVTICGD IHGQFHDLAE LFRIGGKCPD TNYLFMGDYV DRGYYSVETV 100
TLLVALKVRY PQRITILRGN HESRQITQVY GFYDECLRKY GNANVWKTFT 150
DLFDYFPLTA LVESEIFCLH GGLSPSIETL DNIRNFDRVQ EVPHEGAMCD 200
LLWSDPDDRC GWGISPRGAG YTFGQDISEQ FNHTNNLKLI ARAHQLVMEG 250
FNWAHDQKVV TIFSAPNYCY RCGNMASILE VDDSRERTFI QFEPAPRRGE 300
PDVTRRTPDY FL 312
Length:312
Mass (Da):35,639
Last modified:November 1, 1999 - v1
Checksum:iB24F1ABEC2793315
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ007496 mRNA. Translation: CAB46506.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ007496 mRNA. Translation: CAB46506.1 .

3D structure databases

ProteinModelPortali Q9XGH7.
SMRi Q9XGH7. Positions 13-312.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.60.21.10. 1 hit.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF00149. Metallophos. 1 hit.
[Graphical view ]
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 1 hit.
PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Molecular analysis of protein phosphatase 2A in tobacco."
    Remus M., Stitt M., Zrenner R.
    Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. SR1.

Entry informationi

Entry nameiPP2A_TOBAC
AccessioniPrimary (citable) accession number: Q9XGH7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: June 11, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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