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Protein

Probable protein phosphatase 2C 30

Gene

PP2C5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi166 – 1661Manganese 1By similarity
Metal bindingi166 – 1661Manganese 2By similarity
Metal bindingi167 – 1671Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi331 – 3311Manganese 2By similarity
Metal bindingi376 – 3761Manganese 2By similarity

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • protein serine/threonine phosphatase activity Source: TAIR

GO - Biological processi

  • abscisic acid-activated signaling pathway Source: TAIR
  • protein dephosphorylation Source: InterPro
  • stomatal lineage progression Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT2G40180-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 30 (EC:3.1.3.16)
Short name:
AtPP2C30
Alternative name(s):
AthPP2C5
Gene namesi
Name:PP2C5
Ordered Locus Names:At2g40180
ORF Names:T7M7.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G40180.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 390390Probable protein phosphatase 2C 30PRO_0000367958Add
BLAST

Proteomic databases

PRIDEiQ9XEE8.

Expressioni

Gene expression databases

ExpressionAtlasiQ9XEE8. baseline and differential.

Interactioni

Protein-protein interaction databases

BioGridi3947. 3 interactions.
STRINGi3702.AT2G40180.1.

Structurei

3D structure databases

ProteinModelPortaliQ9XEE8.
SMRiQ9XEE8. Positions 136-386.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini128 – 385258PPM-type phosphatasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PPM-type phosphatase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ9XEE8.
OMAiFEFLILA.
PhylomeDBiQ9XEE8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XEE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLSKNPIKQ TRNREKNYTD DFTMKRSVIM APESPVFFPP PLVFSPTSVK
60 70 80 90 100
TPLSSPRSSP PKLTMVACPP RKPKETKTTG SDSETVLKRK RPPMLDLTAA
110 120 130 140 150
PTVASWCSTT RETAEKGAEV VEAEEDGYYS VYCKRGRRGP MEDRYFAAVD
160 170 180 190 200
RNDDGGYKNA FFGVFDGHGG SKAAEFAAMN LGNNIEAAMA SARSGEDGCS
210 220 230 240 250
MESAIREGYI KTDEDFLKEG SRGGACCVTA LISKGELAVS NAGDCRAVMS
260 270 280 290 300
RGGTAEALTS DHNPSQANEL KRIEALGGYV DCCNGVWRIQ GTLAVSRGIG
310 320 330 340 350
DRYLKEWVIA EPETRTLRIK PEFEFLILAS DGLWDKVTNQ EAVDVVRPYC
360 370 380 390
VGVENPMTLS ACKKLAELSV KRGSLDDISL IIIQLQNFLP
Length:390
Mass (Da):42,595
Last modified:November 1, 1999 - v1
Checksum:iF8FD06B046044D60
GO

Sequence cautioni

The sequence AAO42063.1 differs from that shown.Probable cloning artifact leading to a large internal deletion.Curated
The sequence AAO50609.1 differs from that shown.Probable cloning artifact leading to a large internal deletion.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085279 Genomic DNA. Translation: AAD25933.1.
CP002685 Genomic DNA. Translation: AEC09793.1.
BT004027 mRNA. Translation: AAO42063.1. Sequence problems.
BT005076 mRNA. Translation: AAO50609.1. Sequence problems.
PIRiC84826.
RefSeqiNP_181547.1. NM_129576.2.
UniGeneiAt.37092.

Genome annotation databases

EnsemblPlantsiAT2G40180.1; AT2G40180.1; AT2G40180.
GeneIDi818609.
KEGGiath:AT2G40180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085279 Genomic DNA. Translation: AAD25933.1.
CP002685 Genomic DNA. Translation: AEC09793.1.
BT004027 mRNA. Translation: AAO42063.1. Sequence problems.
BT005076 mRNA. Translation: AAO50609.1. Sequence problems.
PIRiC84826.
RefSeqiNP_181547.1. NM_129576.2.
UniGeneiAt.37092.

3D structure databases

ProteinModelPortaliQ9XEE8.
SMRiQ9XEE8. Positions 136-386.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi3947. 3 interactions.
STRINGi3702.AT2G40180.1.

Proteomic databases

PRIDEiQ9XEE8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G40180.1; AT2G40180.1; AT2G40180.
GeneIDi818609.
KEGGiath:AT2G40180.

Organism-specific databases

TAIRiAT2G40180.

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ9XEE8.
OMAiFEFLILA.
PhylomeDBiQ9XEE8.

Enzyme and pathway databases

BioCyciARA:AT2G40180-MONOMER.

Miscellaneous databases

PROiQ9XEE8.

Gene expression databases

ExpressionAtlasiQ9XEE8. baseline and differential.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR015655. PP2C.
IPR000222. PP2C_BS.
IPR001932. PPM-type_phosphatase_dom.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PPM_1. 1 hit.
PS51746. PPM_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07."
    Wang M.L., Belmonte S., Kim U., Dolan M., Morris J.W., Goodman H.M.
    Genome Res. 9:325-333(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C30_ARATH
AccessioniPrimary (citable) accession number: Q9XEE8
Secondary accession number(s): Q84K48
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1999
Last modified: June 24, 2015
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.