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Q9XEE8

- P2C30_ARATH

UniProt

Q9XEE8 - P2C30_ARATH

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Protein

Probable protein phosphatase 2C 30

Gene

PP2C5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi166 – 1661Manganese 1By similarity
Metal bindingi166 – 1661Manganese 2By similarity
Metal bindingi167 – 1671Manganese 1; via carbonyl oxygenBy similarity
Metal bindingi331 – 3311Manganese 2By similarity
Metal bindingi376 – 3761Manganese 2By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. protein serine/threonine phosphatase activity Source: TAIR

GO - Biological processi

  1. abscisic acid-activated signaling pathway Source: TAIR
  2. protein dephosphorylation Source: InterPro
  3. stomatal lineage progression Source: TAIR
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Ligandi

Magnesium, Manganese, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT2G40180-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 30 (EC:3.1.3.16)
Short name:
AtPP2C30
Alternative name(s):
AthPP2C5
Gene namesi
Name:PP2C5
Ordered Locus Names:At2g40180
ORF Names:T7M7.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
ProteomesiUP000006548: Chromosome 2

Organism-specific databases

TAIRiAT2G40180.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: TAIR
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 390390Probable protein phosphatase 2C 30PRO_0000367958Add
BLAST

Proteomic databases

PRIDEiQ9XEE8.

Expressioni

Gene expression databases

ExpressionAtlasiQ9XEE8. baseline and differential.
GenevestigatoriQ9XEE8.

Interactioni

Protein-protein interaction databases

BioGridi3947. 3 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9XEE8.
SMRiQ9XEE8. Positions 136-386.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini127 – 378252PP2C-likeAdd
BLAST

Sequence similaritiesi

Belongs to the PP2C family.Curated
Contains 1 PP2C-like domain.Curated

Phylogenomic databases

eggNOGiCOG0631.
HOGENOMiHOG000233896.
InParanoidiQ9XEE8.
OMAiFEFLILA.
PhylomeDBiQ9XEE8.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
PROSITEiPS01032. PP2C. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XEE8 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQLSKNPIKQ TRNREKNYTD DFTMKRSVIM APESPVFFPP PLVFSPTSVK
60 70 80 90 100
TPLSSPRSSP PKLTMVACPP RKPKETKTTG SDSETVLKRK RPPMLDLTAA
110 120 130 140 150
PTVASWCSTT RETAEKGAEV VEAEEDGYYS VYCKRGRRGP MEDRYFAAVD
160 170 180 190 200
RNDDGGYKNA FFGVFDGHGG SKAAEFAAMN LGNNIEAAMA SARSGEDGCS
210 220 230 240 250
MESAIREGYI KTDEDFLKEG SRGGACCVTA LISKGELAVS NAGDCRAVMS
260 270 280 290 300
RGGTAEALTS DHNPSQANEL KRIEALGGYV DCCNGVWRIQ GTLAVSRGIG
310 320 330 340 350
DRYLKEWVIA EPETRTLRIK PEFEFLILAS DGLWDKVTNQ EAVDVVRPYC
360 370 380 390
VGVENPMTLS ACKKLAELSV KRGSLDDISL IIIQLQNFLP
Length:390
Mass (Da):42,595
Last modified:November 1, 1999 - v1
Checksum:iF8FD06B046044D60
GO

Sequence cautioni

The sequence AAO42063.1 differs from that shown. Reason: Probable cloning artifact leading to a large internal deletion.
The sequence AAO50609.1 differs from that shown. Reason: Probable cloning artifact leading to a large internal deletion.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF085279 Genomic DNA. Translation: AAD25933.1.
CP002685 Genomic DNA. Translation: AEC09793.1.
BT004027 mRNA. Translation: AAO42063.1. Sequence problems.
BT005076 mRNA. Translation: AAO50609.1. Sequence problems.
PIRiC84826.
RefSeqiNP_181547.1. NM_129576.2.
UniGeneiAt.37092.

Genome annotation databases

EnsemblPlantsiAT2G40180.1; AT2G40180.1; AT2G40180.
GeneIDi818609.
KEGGiath:AT2G40180.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF085279 Genomic DNA. Translation: AAD25933.1 .
CP002685 Genomic DNA. Translation: AEC09793.1 .
BT004027 mRNA. Translation: AAO42063.1 . Sequence problems.
BT005076 mRNA. Translation: AAO50609.1 . Sequence problems.
PIRi C84826.
RefSeqi NP_181547.1. NM_129576.2.
UniGenei At.37092.

3D structure databases

ProteinModelPortali Q9XEE8.
SMRi Q9XEE8. Positions 136-386.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 3947. 3 interactions.

Proteomic databases

PRIDEi Q9XEE8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblPlantsi AT2G40180.1 ; AT2G40180.1 ; AT2G40180 .
GeneIDi 818609.
KEGGi ath:AT2G40180.

Organism-specific databases

TAIRi AT2G40180.

Phylogenomic databases

eggNOGi COG0631.
HOGENOMi HOG000233896.
InParanoidi Q9XEE8.
OMAi FEFLILA.
PhylomeDBi Q9XEE8.

Enzyme and pathway databases

BioCyci ARA:AT2G40180-MONOMER.

Gene expression databases

ExpressionAtlasi Q9XEE8. baseline and differential.
Genevestigatori Q9XEE8.

Family and domain databases

Gene3Di 3.60.40.10. 1 hit.
InterProi IPR001932. PP2C-like_dom.
IPR000222. PP2C_Mn2_Asp60_BS.
IPR015655. Protein_Pase_2C.
[Graphical view ]
PANTHERi PTHR13832. PTHR13832. 1 hit.
Pfami PF00481. PP2C. 1 hit.
[Graphical view ]
SMARTi SM00331. PP2C_SIG. 1 hit.
SM00332. PP2Cc. 1 hit.
[Graphical view ]
SUPFAMi SSF81606. SSF81606. 1 hit.
PROSITEi PS01032. PP2C. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A cluster of ABA-regulated genes on Arabidopsis thaliana BAC T07M07."
    Wang M.L., Belmonte S., Kim U., Dolan M., Morris J.W., Goodman H.M.
    Genome Res. 9:325-333(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  3. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  4. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  5. "Genome-wide and expression analysis of protein phosphatase 2C in rice and Arabidopsis."
    Xue T., Wang D., Zhang S., Ehlting J., Ni F., Jacab S., Zheng C., Zhong Y.
    BMC Genomics 9:550-550(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: GENE FAMILY, NOMENCLATURE.

Entry informationi

Entry nameiP2C30_ARATH
AccessioniPrimary (citable) accession number: Q9XEE8
Secondary accession number(s): Q84K48
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3