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Protein

Probable protein phosphatase 2C 30

Gene

PP2C5

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactori

Mg2+By similarity, Mn2+By similarityNote: Binds 2 magnesium or manganese ions per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi166Manganese 1By similarity1
Metal bindingi166Manganese 2By similarity1
Metal bindingi167Manganese 1; via carbonyl oxygenBy similarity1
Metal bindingi331Manganese 2By similarity1
Metal bindingi376Manganese 2By similarity1

GO - Molecular functioni

  • metal ion binding Source: UniProtKB-KW
  • protein serine/threonine phosphatase activity Source: TAIR

GO - Biological processi

  • abscisic acid-activated signaling pathway Source: TAIR
  • stomatal lineage progression Source: TAIR

Keywordsi

Molecular functionHydrolase, Protein phosphatase
LigandMagnesium, Manganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable protein phosphatase 2C 30 (EC:3.1.3.16)
Short name:
AtPP2C30
Alternative name(s):
AthPP2C5
Gene namesi
Name:PP2C5
Ordered Locus Names:At2g40180
ORF Names:T7M7.17
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G40180
TAIRilocus:2065046 AT2G40180

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003679581 – 390Probable protein phosphatase 2C 30Add BLAST390

Proteomic databases

PaxDbiQ9XEE8
PRIDEiQ9XEE8

Expressioni

Gene expression databases

ExpressionAtlasiQ9XEE8 differential
GenevisibleiQ9XEE8 AT

Interactioni

Protein-protein interaction databases

BioGridi3947, 4 interactors
STRINGi3702.AT2G40180.1

Structurei

3D structure databases

ProteinModelPortaliQ9XEE8
SMRiQ9XEE8
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini128 – 385PPM-type phosphatasePROSITE-ProRule annotationAdd BLAST258

Sequence similaritiesi

Belongs to the PP2C family.Curated

Phylogenomic databases

eggNOGiKOG0698 Eukaryota
COG0631 LUCA
HOGENOMiHOG000233896
InParanoidiQ9XEE8
OMAiDCCRGVW
OrthoDBiEOG09360G4V
PhylomeDBiQ9XEE8

Family and domain databases

CDDicd00143 PP2Cc, 1 hit
Gene3Di3.60.40.10, 1 hit
InterProiView protein in InterPro
IPR015655 PP2C
IPR000222 PP2C_BS
IPR036457 PPM-type_dom_sf
IPR001932 PPM-type_phosphatase_dom
PANTHERiPTHR13832 PTHR13832, 1 hit
PfamiView protein in Pfam
PF00481 PP2C, 1 hit
SMARTiView protein in SMART
SM00331 PP2C_SIG, 1 hit
SM00332 PP2Cc, 1 hit
SUPFAMiSSF81606 SSF81606, 1 hit
PROSITEiView protein in PROSITE
PS01032 PPM_1, 1 hit
PS51746 PPM_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9XEE8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQLSKNPIKQ TRNREKNYTD DFTMKRSVIM APESPVFFPP PLVFSPTSVK
60 70 80 90 100
TPLSSPRSSP PKLTMVACPP RKPKETKTTG SDSETVLKRK RPPMLDLTAA
110 120 130 140 150
PTVASWCSTT RETAEKGAEV VEAEEDGYYS VYCKRGRRGP MEDRYFAAVD
160 170 180 190 200
RNDDGGYKNA FFGVFDGHGG SKAAEFAAMN LGNNIEAAMA SARSGEDGCS
210 220 230 240 250
MESAIREGYI KTDEDFLKEG SRGGACCVTA LISKGELAVS NAGDCRAVMS
260 270 280 290 300
RGGTAEALTS DHNPSQANEL KRIEALGGYV DCCNGVWRIQ GTLAVSRGIG
310 320 330 340 350
DRYLKEWVIA EPETRTLRIK PEFEFLILAS DGLWDKVTNQ EAVDVVRPYC
360 370 380 390
VGVENPMTLS ACKKLAELSV KRGSLDDISL IIIQLQNFLP
Length:390
Mass (Da):42,595
Last modified:November 1, 1999 - v1
Checksum:iF8FD06B046044D60
GO

Sequence cautioni

The sequence AAO42063 differs from that shown. Probable cloning artifact leading to a large internal deletion.Curated
The sequence AAO50609 differs from that shown. Probable cloning artifact leading to a large internal deletion.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF085279 Genomic DNA Translation: AAD25933.1
CP002685 Genomic DNA Translation: AEC09793.1
BT004027 mRNA Translation: AAO42063.1 Sequence problems.
BT005076 mRNA Translation: AAO50609.1 Sequence problems.
PIRiC84826
RefSeqiNP_181547.1, NM_129576.3
UniGeneiAt.37092

Genome annotation databases

EnsemblPlantsiAT2G40180.1; AT2G40180.1; AT2G40180
GeneIDi818609
GrameneiAT2G40180.1; AT2G40180.1; AT2G40180
KEGGiath:AT2G40180

Similar proteinsi

Entry informationi

Entry nameiP2C30_ARATH
AccessioniPrimary (citable) accession number: Q9XEE8
Secondary accession number(s): Q84K48
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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