ID   QUIA_XANCJ              Reviewed;         790 AA.
AC   Q9XD78;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1999, sequence version 1.
DT   16-JUN-2009, entry version 57.
DE   RecName: Full=Probable quinate dehydrogenase [Pyrroloquinoline-quinone];
DE            EC=1.1.99.25;
GN   Name=qumA;
OS   Xanthomonas campestris pv. juglandis (Xanthomonas arboricola pv.
OS   juglandis).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
OC   Xanthomonadaceae; Xanthomonas.
OX   NCBI_TaxID=195709;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C5;
RX   MEDLINE=20063481; PubMed=10594704;
RX   DOI=10.1046/j.1365-2672.1999.00864.x;
RA   Lee Y.-A., Lo Y.-C., Yu P.-P.;
RT   "A gene involved in quinate metabolism is specific to one DNA homology
RT   group of Xanthomonas campestris.";
RL   J. Appl. Microbiol. 87:649-658(1999).
CC   -!- CATALYTIC ACTIVITY: Quinate + pyrroloquinoline-quinone = 3-
CC       dehydroquinate + reduced pyrroloquinoline-quinone.
CC   -!- COFACTOR: PQQ (By similarity).
CC   -!- PATHWAY: Aromatic compound metabolism; 3,4-dihydroxybenzoate
CC       biosynthesis; 3-dehydroquinate from quinate (PQQ route): step 1/1.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein
CC       (Potential).
CC   -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
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DR   EMBL; AF109471; AAD38453.1; -; Genomic_DNA.
DR   BRENDA; 1.1.99.25; 295646.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009055; F:electron carrier activity; IEA:InterPro.
DR   GO; GO:0047519; F:quinate dehydrogenase (pyrroloquinoline-qui...; IEA:EC.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0019630; P:quinate metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR017511; PQQ-dep_membr-bd_DH.
DR   InterPro; IPR019556; PQQ-dependent_C.
DR   InterPro; IPR019551; PQQ-dependent_N.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quino_AlcDH-like.
DR   InterPro; IPR001479; Quinoprotein_DH_CS.
DR   Gene3D; G3DSA:2.140.10.10; Quinoprotein_alc_DH-like; 1.
DR   Pfam; PF01011; PQQ; 4.
DR   Pfam; PF10535; PQQ_C; 1.
DR   Pfam; PF10527; PQQ_N; 1.
DR   SMART; SM00564; PQQ; 5.
DR   TIGRFAMs; TIGR03074; PQQ_membr_DH; 1.
DR   PROSITE; PS00363; BACTERIAL_PQQ_1; FALSE_NEG.
DR   PROSITE; PS00364; BACTERIAL_PQQ_2; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Oxidoreductase; PQQ; Quinate metabolism;
KW   Transmembrane.
FT   CHAIN         1    790       Probable quinate dehydrogenase
FT                                [Pyrroloquinoline-quinone].
FT                                /FTId=PRO_0000205341.
FT   TRANSMEM     22     42       Potential.
FT   TRANSMEM     48     68       Potential.
FT   TRANSMEM     77     94       Potential.
FT   TRANSMEM    106    126       Potential.
SQ   SEQUENCE   790 AA;  82897 MW;  B75F29B52A49FE6F CRC64;
     MLIALVGLIF LLGGARLASL GGSWYFLLMG LATALAGVLI VLRRPAGALV YGVAFALTLV
     WALWDAGLEF WPLVSRLMLP AAFAVLVALA WPALRRSRAL PTGRTAYGVA TVLALAVVAG
     IGGMFVPHPP VAGNAGPGMT AVPPGSVQQN WSAYGNTDGG SRFAALDQIN RSNGRPAAGS
     PGPTTPGEIA NSDGNGAEDQ LTPLQVGEKV FLCTPHNNLI ALDASTGKQL WRREINATSS
     VWQRCRGLGY FDADAALPAP SVANPSPIAA VTVAQGANCR RRLFTNTIDG RLIAVDADTG
     AFCQGFGSNG QVDLKAGLGA APDPFYQLTS PPLVAGTTVV GGRTRADDNV QTDMPGGVVR
     GSMWSPVRSA GLDPGNPHDR QAPAAGSSYV RSTPNVWAPM SYDAAMNTVF LPLGGPSTDL
     YGAERTALDH RYGASVLALD ATTGAEKWVY QTVHNDLWDF DLPMQPSLID FPNQDGSHTP
     AVVIGTKAGQ IYVLDRATGK PLTEVREVPV KGSDIAHEQY APTQPLSVGM PQIGTKHLTE
     SDMWGATAMD QMLCRIAFKQ MRYEGLYTAP GTDVSLSFPG SLGGMNWGGL STDPVHDVVF
     ANDMRLGLWV QMIPADTRKA EAAGGGEAVN TGMGAVPLKG TPYAVNKNRF LSALGIPCQA
     PPYGTLSAID LKTRSIAWQV PVGTVQDTGP FGIKMHLPIP IGMPTLGGTL STQGGLVFIA
     GTQDYYLRAF DSATGKELWK GRLPVGSQGG PITYVSHKTG KQYVVISAGG ARQSPDRGDY
     VIAYSLPDAH
//