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Q9XD38

- EFTU_LEPIN

UniProt

Q9XD38 - EFTU_LEPIN

Protein

Elongation factor Tu

Gene

tuf

Organism
Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
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    Functioni

    This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi19 – 268GTPUniRule annotation
    Nucleotide bindingi83 – 875GTPUniRule annotation
    Nucleotide bindingi138 – 1414GTPUniRule annotation

    GO - Molecular functioni

    1. GTPase activity Source: InterPro
    2. GTP binding Source: UniProtKB-HAMAP
    3. translation elongation factor activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Elongation factor

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciLINT189518:GJBB-595-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:LA_0737
    OrganismiLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
    Taxonomic identifieri189518 [NCBI]
    Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
    ProteomesiUP000001408: Chromosome I

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Elongation factor TuPRO_0000091340Add
    BLAST

    Proteomic databases

    PaxDbiQ9XD38.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Structurei

    3D structure databases

    ProteinModelPortaliQ9XD38.
    SMRiQ9XD38. Positions 2-399.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini10 – 211202tr-type GAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni19 – 268G1By similarity
    Regioni62 – 665G2By similarity
    Regioni83 – 864G3By similarity
    Regioni138 – 1414G4By similarity
    Regioni179 – 1813G5By similarity

    Sequence similaritiesi

    Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0050.
    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiGTEMCMP.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9XD38-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKEKFDRSK PHLNVGTIGH VDHGKTTLTA AITTTLAKAI GGKNKAVAYD    50
    QIDNAPEEKA RGITIATSHQ EYETANRHYA HVDCPGHADY VKNMITGAAQ 100
    MDAAILVVSA TDGPMPQTKE HILLARQVGV PYVIVFINKA DMLAADERAE 150
    MIEMVEMDVR ELLNKYSFPG DTTPIVHGSA VKALEGDESE IGMPAILKLM 200
    EALDTFVPNP KRVIDKPFLM PVEDVFSITG RGTVATGRVE QGVLKVNDEV 250
    EIIGIRPTTK TVVTGIEMFR KLLDQAEAGD NIGALLRGTK KEEIERGQVL 300
    AKPGSITPHK KFAAEVYVLT KDEGGRHTPF INNYRPQFYF RTTDVTGVCN 350
    LPNGVEMVMP GDNVSLTVEL ISPIAMDKGL KFAIREGGRT IGSGVVAEIT 400
    E 401
    Length:401
    Mass (Da):43,574
    Last modified:November 1, 1999 - v1
    Checksum:iB8ED827C1A717BA0
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF115283 Genomic DNA. Translation: AAD40614.1.
    AE010300 Genomic DNA. Translation: AAN47936.1.
    RefSeqiNP_710918.1. NC_004342.2.
    WP_001040571.1. NC_004342.2.

    Genome annotation databases

    EnsemblBacteriaiAAN47936; AAN47936; LA_0737.
    GeneIDi1150080.
    KEGGilil:LA_0737.
    PATRICi22382328. VBILepInt91350_0741.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF115283 Genomic DNA. Translation: AAD40614.1 .
    AE010300 Genomic DNA. Translation: AAN47936.1 .
    RefSeqi NP_710918.1. NC_004342.2.
    WP_001040571.1. NC_004342.2.

    3D structure databases

    ProteinModelPortali Q9XD38.
    SMRi Q9XD38. Positions 2-399.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PaxDbi Q9XD38.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAN47936 ; AAN47936 ; LA_0737 .
    GeneIDi 1150080.
    KEGGi lil:LA_0737.
    PATRICi 22382328. VBILepInt91350_0741.

    Phylogenomic databases

    eggNOGi COG0050.
    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi GTEMCMP.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci LINT189518:GJBB-595-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. G_TR_1. 1 hit.
    PS51722. G_TR_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Characterization of the Leptospira interrogans S10-spc-alpha operon."
      Zuerner R.L., Hartskeerl R.A., van de Kemp H., Bal A.E.
      FEMS Microbiol. Lett. 182:303-308(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Lai / Serogroup Icterohaemorrhagiae / Serovar lai.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 56601.

    Entry informationi

    Entry nameiEFTU_LEPIN
    AccessioniPrimary (citable) accession number: Q9XD38
    Secondary accession number(s): Q7CM62
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 15, 2005
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3