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Q9XD38 (EFTU_LEPIN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 87. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Elongation factor Tu

Short name=EF-Tu
Gene names
Name:tuf
Ordered Locus Names:LA_0737
OrganismLeptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601) [Reference proteome] [HAMAP]
Taxonomic identifier189518 [NCBI]
Taxonomic lineageBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira

Protein attributes

Sequence length401 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity. HAMAP-Rule MF_00118

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00118

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00118.

Sequence similarities

Belongs to the GTP-binding elongation factor family. EF-Tu/EF-1A subfamily.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandGTP-binding
Nucleotide-binding
   Molecular functionElongation factor
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionGTP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

GTPase activity

Inferred from electronic annotation. Source: InterPro

translation elongation factor activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 401401Elongation factor Tu HAMAP-Rule MF_00118
PRO_0000091340

Regions

Nucleotide binding19 – 268GTP By similarity
Nucleotide binding83 – 875GTP By similarity
Nucleotide binding138 – 1414GTP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9XD38 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: B8ED827C1A717BA0

FASTA40143,574
        10         20         30         40         50         60 
MAKEKFDRSK PHLNVGTIGH VDHGKTTLTA AITTTLAKAI GGKNKAVAYD QIDNAPEEKA 

        70         80         90        100        110        120 
RGITIATSHQ EYETANRHYA HVDCPGHADY VKNMITGAAQ MDAAILVVSA TDGPMPQTKE 

       130        140        150        160        170        180 
HILLARQVGV PYVIVFINKA DMLAADERAE MIEMVEMDVR ELLNKYSFPG DTTPIVHGSA 

       190        200        210        220        230        240 
VKALEGDESE IGMPAILKLM EALDTFVPNP KRVIDKPFLM PVEDVFSITG RGTVATGRVE 

       250        260        270        280        290        300 
QGVLKVNDEV EIIGIRPTTK TVVTGIEMFR KLLDQAEAGD NIGALLRGTK KEEIERGQVL 

       310        320        330        340        350        360 
AKPGSITPHK KFAAEVYVLT KDEGGRHTPF INNYRPQFYF RTTDVTGVCN LPNGVEMVMP 

       370        380        390        400 
GDNVSLTVEL ISPIAMDKGL KFAIREGGRT IGSGVVAEIT E 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF115283 Genomic DNA. Translation: AAD40614.1.
AE010300 Genomic DNA. Translation: AAN47936.1.
RefSeqNP_710918.1. NC_004342.2.

3D structure databases

ProteinModelPortalQ9XD38.
SMRQ9XD38. Positions 2-399.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PaxDbQ9XD38.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAN47936; AAN47936; LA_0737.
GeneID1150080.
KEGGlil:LA_0737.
PATRIC22382328. VBILepInt91350_0741.

Phylogenomic databases

eggNOGCOG0050.
HOGENOMHOG000229290.
KOK02358.
OMAGTEMCMP.
OrthoDBEOG6R5C6X.

Enzyme and pathway databases

BioCycLINT189518:GJBB-595-MONOMER.

Family and domain databases

Gene3D3.40.50.300. 1 hit.
HAMAPMF_00118_B. EF_Tu_B.
InterProIPR000795. EF_GTP-bd_dom.
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR009000. Transl_B-barrel.
IPR009001. Transl_elong_EF1A/Init_IF2_C.
IPR004161. Transl_elong_EFTu/EF1A_2.
IPR004541. Transl_elong_EFTu/EF1A_bac/org.
IPR004160. Transl_elong_EFTu/EF1A_C.
[Graphical view]
PfamPF00009. GTP_EFTU. 1 hit.
PF03144. GTP_EFTU_D2. 1 hit.
PF03143. GTP_EFTU_D3. 1 hit.
[Graphical view]
PRINTSPR00315. ELONGATNFCT.
SUPFAMSSF50447. SSF50447. 1 hit.
SSF50465. SSF50465. 1 hit.
SSF52540. SSF52540. 1 hit.
TIGRFAMsTIGR00485. EF-Tu. 1 hit.
TIGR00231. small_GTP. 1 hit.
PROSITEPS00301. EFACTOR_GTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEFTU_LEPIN
AccessionPrimary (citable) accession number: Q9XD38
Secondary accession number(s): Q7CM62
Entry history
Integrated into UniProtKB/Swiss-Prot: February 15, 2005
Last sequence update: November 1, 1999
Last modified: June 11, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families