Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9XC48

- Q9XC48_9ACTO

UniProt

Q9XC48 - Q9XC48_9ACTO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Peptide synthetase NRPS type II-PCP

Gene

blmI

Organism
Streptomyces verticillus
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Peptide synthetase NRPS type II-PCPImported
Gene namesi
Name:blmIImported
OrganismiStreptomyces verticillusImported
Taxonomic identifieri29309 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

PTM / Processingi

Keywords - PTMi

PhosphopantetheineUniRule annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4NEOX-ray2.10A2-90[»]
ProteinModelPortaliQ9XC48.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
InterProiIPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XC48-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSAPRGERTR RRALERDIAA IWAETLGRDS VGPHEDFAAL GGNSIHAIKI
60 70 80 90
TNRVEELVDA ELSIRVLLET RTVAGMTDHV HATLTGERDR
Length:90
Mass (Da):9,957
Last modified:November 1, 1999 - v1
Checksum:iD28FDB4C4D2D4C8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF210249 Genomic DNA. Translation: AAD42077.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF210249 Genomic DNA. Translation: AAD42077.1 .

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4NEO X-ray 2.10 A 2-90 [» ]
ProteinModelPortali Q9XC48.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.1200.10. 1 hit.
InterProi IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view ]
Pfami PF00550. PP-binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47336. SSF47336. 1 hit.
PROSITEi PS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003."
    Du L., Shen B.
    Chem. Biol. 6:507-517(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC15003Imported.
  2. "The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase."
    Du L., Sanchez C., Chen M., Edwards D.J., Shen B.
    Chem. Biol. 7:623-642(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC15003Imported.
  3. "An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003."
    Du L., Chen M., Sanchez C., Shen B.
    FEMS Microbiol. Lett. 189:171-175(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC15003Imported.
  4. "The crystal structure of BlmI as a model for nonribosomal peptide synthetase peptidyl carrier proteins."
    Lohman J.R., Ma M., Cuff M.E., Bigelow L., Bearden J., Babnigg G., Joachimiak A., Phillips G.N., Shen B.
    Proteins 82:1210-1218(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 2-90.

Entry informationi

Entry nameiQ9XC48_9ACTO
AccessioniPrimary (citable) accession number: Q9XC48
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3