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Q9XC48

- Q9XC48_9ACTO

UniProt

Q9XC48 - Q9XC48_9ACTO

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Protein
Submitted name: Peptide synthetase NRPS type II-PCP
Gene
blmI
Organism
Streptomyces verticillus
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Peptide synthetase NRPS type II-PCPImported
Gene namesi
Name:blmIImported
OrganismiStreptomyces verticillusImported
Taxonomic identifieri29309 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces

PTM / Processingi

Keywords - PTMi

PhosphopantetheineUniRule annotation

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4NEOX-ray2.10A2-90[»]
ProteinModelPortaliQ9XC48.

Family & Domainsi

Family and domain databases

Gene3Di1.10.1200.10. 1 hit.
InterProiIPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view]
PfamiPF00550. PP-binding. 1 hit.
[Graphical view]
SUPFAMiSSF47336. SSF47336. 1 hit.
PROSITEiPS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XC48-1 [UniParc]FASTAAdd to Basket

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MSAPRGERTR RRALERDIAA IWAETLGRDS VGPHEDFAAL GGNSIHAIKI   50
TNRVEELVDA ELSIRVLLET RTVAGMTDHV HATLTGERDR 90
Length:90
Mass (Da):9,957
Last modified:November 1, 1999 - v1
Checksum:iD28FDB4C4D2D4C8C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF210249 Genomic DNA. Translation: AAD42077.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF210249 Genomic DNA. Translation: AAD42077.1 .

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
4NEO X-ray 2.10 A 2-90 [» ]
ProteinModelPortali Q9XC48.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.10.1200.10. 1 hit.
InterProi IPR009081. Acyl_carrier_prot-like.
IPR006162. PPantetheine_attach_site.
[Graphical view ]
Pfami PF00550. PP-binding. 1 hit.
[Graphical view ]
SUPFAMi SSF47336. SSF47336. 1 hit.
PROSITEi PS50075. ACP_DOMAIN. 1 hit.
PS00012. PHOSPHOPANTETHEINE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification and characterization of a type II peptidyl carrier protein from the bleomycin producer Streptomyces verticillus ATCC 15003."
    Du L., Shen B.
    Chem. Biol. 6:507-517(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC15003Imported.
  2. "The biosynthetic gene cluster for the antitumor drug bleomycin from Streptomyces verticillus ATCC15003 supporting functional interactions between nonribosomal peptide synthetases and a polyketide synthase."
    Du L., Sanchez C., Chen M., Edwards D.J., Shen B.
    Chem. Biol. 7:623-642(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC15003Imported.
  3. "An oxidation domain in the BlmIII non-ribosomal peptide synthetase probably catalyzing thiazole formation in the biosynthesis of the anti-tumor drug bleomycin in Streptomyces verticillus ATCC15003."
    Du L., Chen M., Sanchez C., Shen B.
    FEMS Microbiol. Lett. 189:171-175(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: ATCC15003Imported.
  4. "Structure of BlmI, a type-II acyl-carrier-protein from Streptomyces verticillus involved in bleomycin biosynthesis."
    Cuff M.E., Bigelow L., Bearden J., Babnigg G., Bruno C.J.P., Bingman C., Yennamalli R., Lohman J., Ma M., Shen B., Phillips Jr. G.N., Joachimiak A.
    Submitted (OCT-2013) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 2-90.

Entry informationi

Entry nameiQ9XC48_9ACTO
AccessioniPrimary (citable) accession number: Q9XC48
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: March 19, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

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