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Q9XC20 (RIR2_MYCGA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase subunit beta

EC=1.17.4.1
Alternative name(s):
Ribonucleotide reductase small subunit
Gene names
Name:nrdF
Ordered Locus Names:MYCGA0450
ORF Names:MGA_0698
OrganismMycoplasma gallisepticum (strain R(low / passage 15 / clone 2)) [Complete proteome] [HAMAP]
Taxonomic identifier710127 [NCBI]
Taxonomic lineageBacteriaTenericutesMollicutesMycoplasmataceaeMycoplasma

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity.

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin.

Cofactor

Binds 2 iron ions per subunit By similarity.

Pathway

Genetic information processing; DNA replication.

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family.

Caution

Seems to lack two of the iron-binding residues.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 339339Ribonucleoside-diphosphate reductase subunit beta
PRO_0000190482

Sites

Active site1251 By similarity
Metal binding871Iron 1 By similarity
Metal binding1211Iron 1 By similarity
Metal binding2151Iron 2

Sequences

Sequence LengthMass (Da)Tools
Q9XC20 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: A8711B1B51E4F47F

FASTA33939,168
        10         20         30         40         50         60 
MSNNNKYYDK SFSPLGYVAN GQKGVMRSIN WNVINDPKDL EVWTRVTQNF WLPEKIPVSN 

        70         80         90        100        110        120 
DLKSWNELTP EWKQLVTRTF TGLTLLDTIQ CTLGDIAQIP NSLTDHEQFV YANFSFMVGV 

       130        140        150        160        170        180 
HARSYGTIFS TLNTSDEIEE AHEWVINNEK LQARAKFLVP YYTSDDPLKS KIAAALMPGF 

       190        200        210        220        230        240 
LLYGGFYLPF YLAARGKLPN TSDIIRLILR DKVIHNYYSG YKYRLKVQKL PKEKQEEYKK 

       250        260        270        280        290        300 
FVFEILYKLI ELEKDFLREL YDGFGLADEA IAFSLYNAGK FLQNCGYESP FTPEETKISP 

       310        320        330 
EVFAQLSARA DENHDFFSGN GSSYIMGVTE ETQDDDWEF 

« Hide

References

« Hide 'large scale' references
[1]Skamrov A.V., Gol'dman M.A., Feoktistova E.S., Bibilashvili R.S.
Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: A5969Var.B.
[2]"The complete genome sequence of the avian pathogen Mycoplasma gallisepticum strain R(low)."
Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F., Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.
Microbiology 149:2307-2316(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: R(low / passage 15 / clone 2).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF152114 Genomic DNA. Translation: AAD45275.1.
AE015450 Genomic DNA. Translation: AAP56395.1.
RefSeqNP_852827.1. NC_004829.2.

3D structure databases

ProteinModelPortalQ9XC20.
SMRQ9XC20. Positions 22-307.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING233150.MGA_0698.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP56395; AAP56395; MGA_0698.
GeneID1090094.
KEGGmga:MGA_0698.
PATRIC20007760. VBIMycGal115357_0048.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0208.
HOGENOMHOG000246153.
KOK00526.
OMANIAFMQS.
OrthoDBEOG68DD19.
ProtClustDBPRK09614.

Enzyme and pathway databases

BioCycMGAL710127:GC09-45-MONOMER.
UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026494. RNR_1b_NrdF.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
SUPFAMSSF47240. SSF47240. 1 hit.
TIGRFAMsTIGR04171. RNR_1b_NrdF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIR2_MYCGA
AccessionPrimary (citable) accession number: Q9XC20
Entry history
Integrated into UniProtKB/Swiss-Prot: December 6, 2002
Last sequence update: November 1, 1999
Last modified: February 19, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways