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Protein

Flagellin A

Gene

flaA

Organism
Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Important for motility and virulence.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Virulence

Enzyme and pathway databases

BioCyciHFEL936155:GHMC-394-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellin A
Gene namesi
Name:flaA
Ordered Locus Names:Hfelis_04060
OrganismiHelicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1)
Taxonomic identifieri936155 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000007934 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 513512Flagellin APRO_0000182607Add
BLAST

Interactioni

Subunit structurei

Heteropolymer of FlaA and FlaB. FlaB is located proximal to the hook while the remainder of the filament is composed of the predominant FlaA.

Protein-protein interaction databases

STRINGi936155.HFELIS_04060.

Structurei

3D structure databases

ProteinModelPortaliQ9XB38.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial flagellin family.Curated

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
KOiK02406.
OMAiMALRVNF.
OrthoDBiPOG091H04B6.

Family and domain databases

Gene3Di1.20.1330.10. 2 hits.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR010810. Flagellin_hook_IN_motif.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF07196. Flagellin_IN. 2 hits.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9XB38-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFQVNTNIN ALNAHAMGLV TQRELKESLE RLSSGLRINK AADDASGMTI
60 70 80 90 100
ADSLRSQAKS LGQAIANTND GMGIIQIADK AMDEQIKILD TIKVKATQAA
110 120 130 140 150
QDGQNTQSRK ALQADIVRLI QSLDNIGNTT SYNGQTLLSG AFSNKEFQVG
160 170 180 190 200
AYSNETIKAS IGSATSDKIG QVKITTGKNI TASGEVALTF KQVDGVHDVS
210 220 230 240 250
LESVKISTSA GTGLGVLAEV INKNSNATGV RATANVITTS DSAIKSGSLS
260 270 280 290 300
SLTVNGIEIG NILGIKKNDS DGRLVAALNA VTAQTGVEAY TDSVGRLNLR
310 320 330 340 350
SIDGRGINIK ANSTNVDGQA SALTTLNGGQ DITRGSTNFG RLSLVRQDAR
360 370 380 390 400
DILVVSGANV SASAGYAAIG FAKGTTANTT VNLRDVLGEF NQAVRSASGA
410 420 430 440 450
NYNKTLASEN LTLGSGVTTL RGAMVVMDIA ESAQKMLDKV RSDLGSVQNQ
460 470 480 490 500
MVSTVNNITI TQVNVKAAES QIRDVDFAQE SANFSKNNIL AQSGSYAMSQ
510
ANTVQQNILR LLT
Length:513
Mass (Da):53,529
Last modified:January 23, 2007 - v3
Checksum:iA48F724F272C256A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11601 Genomic DNA. Translation: CAB46858.1.
FQ670179 Genomic DNA. Translation: CBY82490.1.
RefSeqiWP_013468860.1. NC_014810.2.

Genome annotation databases

EnsemblBacteriaiCBY82490; CBY82490; HFELIS_04060.
KEGGihfe:HFELIS_04060.
PATRICi45238646. VBIHelFel178703_0429.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y11601 Genomic DNA. Translation: CAB46858.1.
FQ670179 Genomic DNA. Translation: CBY82490.1.
RefSeqiWP_013468860.1. NC_014810.2.

3D structure databases

ProteinModelPortaliQ9XB38.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi936155.HFELIS_04060.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCBY82490; CBY82490; HFELIS_04060.
KEGGihfe:HFELIS_04060.
PATRICi45238646. VBIHelFel178703_0429.

Phylogenomic databases

eggNOGiENOG4105I03. Bacteria.
COG1344. LUCA.
HOGENOMiHOG000255144.
KOiK02406.
OMAiMALRVNF.
OrthoDBiPOG091H04B6.

Enzyme and pathway databases

BioCyciHFEL936155:GHMC-394-MONOMER.

Family and domain databases

Gene3Di1.20.1330.10. 2 hits.
InterProiIPR001492. Flagellin.
IPR001029. Flagellin_D0/D1.
IPR010810. Flagellin_hook_IN_motif.
[Graphical view]
PfamiPF00700. Flagellin_C. 1 hit.
PF07196. Flagellin_IN. 2 hits.
PF00669. Flagellin_N. 1 hit.
[Graphical view]
PRINTSiPR00207. FLAGELLIN.
ProtoNetiSearch...

Entry informationi

Entry nameiFLAA_HELFC
AccessioniPrimary (citable) accession number: Q9XB38
Secondary accession number(s): E7A9B2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 76 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.