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Q9XAT2

- PUR5_RHILE

UniProt

Q9XAT2 - PUR5_RHILE

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM
Organism
Rhizobium leguminosarum
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
OrganismiRhizobium leguminosarum
Taxonomic identifieri384 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesRhizobiaceaeRhizobium/Agrobacterium groupRhizobium

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 357357Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_0000148237Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ9XAT2.
SMRiQ9XAT2. Positions 8-343.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9XAT2-1 [UniParc]FASTAAdd to Basket

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MSQSGKNGLT YSDAGVDIDA GNLLVEKIKP AVRSTRRPGG DGEIGGFGGL    50
FDLKAAAFTD PVLVAANDGV GTKLKIAIDA DYHDTVGIDL VAMCVNDLVV 100
QGAEPLFFLD YFATGKLDPD QGAAIVGGIA ARCREAGCAL IGGETAEMPG 150
MYSSGDYDLA GFAVGAAERG KLLPSGDIAE GDVILGLASS GVHSNGFSLV 200
RKIVELSGLD WSAAAPFAER RLLGEALLEP TRIYVKPLLK AIRETGAIKA 250
LAHITGGGFP ENIPRVLPKH LAAEIDLDAV KVPPVFSWLA KTGGVESREM 300
LRTFNCGVGM IAVVAAENVA AVSEALEAEG ETVITLGRMI VRDEGAAGTV 350
YKGTLAI 357
Length:357
Mass (Da):36,910
Last modified:November 1, 1999 - v1
Checksum:i6B5A0EF10334BE0E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ243305 Genomic DNA. Translation: CAB46525.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ243305 Genomic DNA. Translation: CAB46525.1 .

3D structure databases

ProteinModelPortali Q9XAT2.
SMRi Q9XAT2. Positions 8-343.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "The purMN genes of Rhizobium leguminosarum and a superficial link with siderophore production."
    Stevens J.B., De Luca N.G., Beringer J.E., Ringer J.P., Yeoman K.H., Johnston A.W.B.
    Mol. Plant Microbe Interact. 13:228-231(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiPUR5_RHILE
AccessioniPrimary (citable) accession number: Q9XAT2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: November 1, 1999
Last modified: April 16, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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