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Q9XA16

- PKNX_STRCO

UniProt

Q9XA16 - PKNX_STRCO

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Protein

Probable serine/threonine-protein kinase SCO3848

Gene

SCO3848

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei40 – 401ATPPROSITE-ProRule annotation
Active sitei138 – 1381Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi17 – 259ATPPROSITE-ProRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. penicillin binding Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Probable serine/threonine-protein kinase SCO3848 (EC:2.7.11.1)
Gene namesi
Ordered Locus Names:SCO3848
ORF Names:SCH69.18
OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Taxonomic identifieri100226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
ProteomesiUP000001973: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 673673Probable serine/threonine-protein kinase SCO3848PRO_0000171237Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi100226.SCO3848.

Structurei

3D structure databases

ProteinModelPortaliQ9XA16.
SMRiQ9XA16. Positions 4-273.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini11 – 277267Protein kinasePROSITE-ProRule annotationAdd
BLAST
Domaini379 – 44567PASTA 1PROSITE-ProRule annotationAdd
BLAST
Domaini446 – 51166PASTA 2PROSITE-ProRule annotationAdd
BLAST
Domaini512 – 58069PASTA 3PROSITE-ProRule annotationAdd
BLAST
Domaini581 – 64969PASTA 4PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
Contains 4 PASTA domains.PROSITE-ProRule annotation
Contains 1 protein kinase domain.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000037185.
InParanoidiQ9XA16.
KOiK08884.
OMAiIKIMRAD.
OrthoDBiEOG6B35XT.
PhylomeDBiQ9XA16.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00740. PASTA. 4 hits.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9XA16-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MEEPRRLGGR YELGPVLGRG GMAEVYHAHD TRLGRQVAVK TLRADLARDP
60 70 80 90 100
SFQARFRREA QSAASLNHPA IVAVYDTGED YIDNVSIPYI VMEYVDGSTL
110 120 130 140 150
RELLHSGRKL LPERTLEMTI GILQALEYSH RAGIVHRDIK PANVMLTRNG
160 170 180 190 200
QVKVMDFGIA RAMGDSGMTM TQTAAVIGTA QYLSPEQAKG EQVDARSDLY
210 220 230 240 250
STGCLLYELL TVRPPFVGDS PVAVAYQHVR EEPQAPSVFD PEITPEMDAI
260 270 280 290 300
VLKALVKDPD YRYQSADEMR VDIEACLDGQ PVGATAAMGA MAAGGYGAYP
310 320 330 340 350
DDQPTTALRS DGGGGATTML PPMNPDDGGY GYDERPDRRR QQPRKKNTST
360 370 380 390 400
IFLVLAGVLV LVGAILIGKY AFSGDGGPGN DKVPVPAFIG LSKADAQQQA
410 420 430 440 450
DNIDLVLTFK QQECEDQPKG NICAQDPKQG TDVDKESTVN LVVSTGAPKV
460 470 480 490 500
AVPNVIDKNI DEAKKQLEDK GFEVETKQTE SSQDEGTILS QNPDPGKELE
510 520 530 540 550
KGSTVTLEVA KAEEKATVPD VVGRTCDEAK AQVESGGDLT AVCTDQPTND
560 570 580 590 600
PNQVGKVIST TPQSSTQVDP GSKVTIVVGK AVEKTKVPEV RGKTLAEARQ
610 620 630 640 650
ILQQSGFTNV QVAQGSPGDD NAKVFASNPQ PGSEVDDPAA TPITLMTVPG
660 670
DGGNGNGGNG NGGAIAGLPG FGD
Length:673
Mass (Da):71,488
Last modified:November 1, 1999 - v1
Checksum:i42A0615E239722DE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939118 Genomic DNA. Translation: CAB45215.1.
PIRiT36717.
RefSeqiNP_628036.1. NC_003888.3.

Genome annotation databases

EnsemblBacteriaiCAB45215; CAB45215; CAB45215.
GeneIDi1099284.
KEGGisco:SCO3848.
PATRICi23737472. VBIStrCoe124346_3919.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL939118 Genomic DNA. Translation: CAB45215.1 .
PIRi T36717.
RefSeqi NP_628036.1. NC_003888.3.

3D structure databases

ProteinModelPortali Q9XA16.
SMRi Q9XA16. Positions 4-273.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 100226.SCO3848.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAB45215 ; CAB45215 ; CAB45215 .
GeneIDi 1099284.
KEGGi sco:SCO3848.
PATRICi 23737472. VBIStrCoe124346_3919.

Phylogenomic databases

eggNOGi COG0515.
HOGENOMi HOG000037185.
InParanoidi Q9XA16.
KOi K08884.
OMAi IKIMRAD.
OrthoDBi EOG6B35XT.
PhylomeDBi Q9XA16.

Family and domain databases

InterProi IPR011009. Kinase-like_dom.
IPR005543. PASTA_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view ]
Pfami PF03793. PASTA. 4 hits.
PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00740. PASTA. 4 hits.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS51178. PASTA. 4 hits.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-471 / A3(2) / M145.

Entry informationi

Entry nameiPKNX_STRCO
AccessioniPrimary (citable) accession number: Q9XA16
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2003
Last sequence update: November 1, 1999
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3