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Q9XA16

- PKNX_STRCO

UniProt

Q9XA16 - PKNX_STRCO

Protein

Probable serine/threonine-protein kinase SCO3848

Gene

SCO3848

Organism
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei40 – 401ATPPROSITE-ProRule annotation
    Active sitei138 – 1381Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi17 – 259ATPPROSITE-ProRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. penicillin binding Source: InterPro
    3. protein serine/threonine kinase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable serine/threonine-protein kinase SCO3848 (EC:2.7.11.1)
    Gene namesi
    Ordered Locus Names:SCO3848
    ORF Names:SCH69.18
    OrganismiStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    Taxonomic identifieri100226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group
    ProteomesiUP000001973: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 673673Probable serine/threonine-protein kinase SCO3848PRO_0000171237Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi100226.SCO3848.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9XA16.
    SMRiQ9XA16. Positions 4-273.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini11 – 277267Protein kinasePROSITE-ProRule annotationAdd
    BLAST
    Domaini379 – 44567PASTA 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini446 – 51166PASTA 2PROSITE-ProRule annotationAdd
    BLAST
    Domaini512 – 58069PASTA 3PROSITE-ProRule annotationAdd
    BLAST
    Domaini581 – 64969PASTA 4PROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.PROSITE-ProRule annotation
    Contains 4 PASTA domains.PROSITE-ProRule annotation
    Contains 1 protein kinase domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiCOG0515.
    HOGENOMiHOG000037185.
    KOiK08884.
    OMAiIKIMRAD.
    OrthoDBiEOG6B35XT.
    PhylomeDBiQ9XA16.

    Family and domain databases

    InterProiIPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view]
    PfamiPF03793. PASTA. 4 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00740. PASTA. 4 hits.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS51178. PASTA. 4 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9XA16-1 [UniParc]FASTAAdd to Basket

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    MEEPRRLGGR YELGPVLGRG GMAEVYHAHD TRLGRQVAVK TLRADLARDP    50
    SFQARFRREA QSAASLNHPA IVAVYDTGED YIDNVSIPYI VMEYVDGSTL 100
    RELLHSGRKL LPERTLEMTI GILQALEYSH RAGIVHRDIK PANVMLTRNG 150
    QVKVMDFGIA RAMGDSGMTM TQTAAVIGTA QYLSPEQAKG EQVDARSDLY 200
    STGCLLYELL TVRPPFVGDS PVAVAYQHVR EEPQAPSVFD PEITPEMDAI 250
    VLKALVKDPD YRYQSADEMR VDIEACLDGQ PVGATAAMGA MAAGGYGAYP 300
    DDQPTTALRS DGGGGATTML PPMNPDDGGY GYDERPDRRR QQPRKKNTST 350
    IFLVLAGVLV LVGAILIGKY AFSGDGGPGN DKVPVPAFIG LSKADAQQQA 400
    DNIDLVLTFK QQECEDQPKG NICAQDPKQG TDVDKESTVN LVVSTGAPKV 450
    AVPNVIDKNI DEAKKQLEDK GFEVETKQTE SSQDEGTILS QNPDPGKELE 500
    KGSTVTLEVA KAEEKATVPD VVGRTCDEAK AQVESGGDLT AVCTDQPTND 550
    PNQVGKVIST TPQSSTQVDP GSKVTIVVGK AVEKTKVPEV RGKTLAEARQ 600
    ILQQSGFTNV QVAQGSPGDD NAKVFASNPQ PGSEVDDPAA TPITLMTVPG 650
    DGGNGNGGNG NGGAIAGLPG FGD 673
    Length:673
    Mass (Da):71,488
    Last modified:November 1, 1999 - v1
    Checksum:i42A0615E239722DE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939118 Genomic DNA. Translation: CAB45215.1.
    PIRiT36717.
    RefSeqiNP_628036.1. NC_003888.3.

    Genome annotation databases

    EnsemblBacteriaiCAB45215; CAB45215; CAB45215.
    GeneIDi1099284.
    KEGGisco:SCO3848.
    PATRICi23737472. VBIStrCoe124346_3919.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL939118 Genomic DNA. Translation: CAB45215.1 .
    PIRi T36717.
    RefSeqi NP_628036.1. NC_003888.3.

    3D structure databases

    ProteinModelPortali Q9XA16.
    SMRi Q9XA16. Positions 4-273.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 100226.SCO3848.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB45215 ; CAB45215 ; CAB45215 .
    GeneIDi 1099284.
    KEGGi sco:SCO3848.
    PATRICi 23737472. VBIStrCoe124346_3919.

    Phylogenomic databases

    eggNOGi COG0515.
    HOGENOMi HOG000037185.
    KOi K08884.
    OMAi IKIMRAD.
    OrthoDBi EOG6B35XT.
    PhylomeDBi Q9XA16.

    Family and domain databases

    InterProi IPR011009. Kinase-like_dom.
    IPR005543. PASTA_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    [Graphical view ]
    Pfami PF03793. PASTA. 4 hits.
    PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00740. PASTA. 4 hits.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS51178. PASTA. 4 hits.
    PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC BAA-471 / A3(2) / M145.

    Entry informationi

    Entry nameiPKNX_STRCO
    AccessioniPrimary (citable) accession number: Q9XA16
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 4, 2003
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3