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Q9X812 (COX4_STRCO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable cytochrome c oxidase polypeptide 4

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 4
Cytochrome c oxidase polypeptide IV
Gene names
Name:ctaF
Ordered Locus Names:SCO2154
ORF Names:SC6G10.27c
OrganismStreptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) [Reference proteome] [HAMAP]
Taxonomic identifier100226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomycesStreptomyces albidoflavus group

Protein attributes

Sequence length132 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Part of cytochrome c oxidase, its function is unknown By similarity.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subunit structure

Associates with subunits I, II and III to form cytochrome c oxidase By similarity.

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase bacterial subunit CtaF family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 132132Probable cytochrome c oxidase polypeptide 4
PRO_0000220022

Regions

Transmembrane5 – 2521Helical; Potential
Transmembrane33 – 5321Helical; Potential
Transmembrane88 – 10821Helical; Potential
Transmembrane110 – 12718Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9X812 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 12A6AFCFC3376438

FASTA13214,581
        10         20         30         40         50         60 
MKIQGKMFIW LSVFILAVAV VYGYWSKEPA GTTALFLAFG LAIMIGFYLA FTARRVDAGA 

        70         80         90        100        110        120 
QDDMEADVAD EAGEVGFFSP HSWQPLSLAV GGALAFLGIA VGWWVMYFSA PILMVGLFGW 

       130 
VFEYYRGENR TQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL939111 Genomic DNA. Translation: CAB39881.1.
PIRT35536.
RefSeqNP_626410.1. NC_003888.3.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING100226.SCO2154.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAB39881; CAB39881; CAB39881.
GeneID1097588.
KEGGsco:SCO2154.
PATRIC23733960. VBIStrCoe124346_2189.

Phylogenomic databases

eggNOGNOG07397.
HOGENOMHOG000237887.
OMAGTYFRFV.
OrthoDBEOG63FW2X.
PhylomeDBQ9X812.

Family and domain databases

InterProIPR021050. Cyt_c_oxidase_su4_actinobac.
[Graphical view]
PfamPF12270. Cyt_c_ox_IV. 1 hit.
[Graphical view]
PIRSFPIRSF017385. CtaF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCOX4_STRCO
AccessionPrimary (citable) accession number: Q9X812
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: November 1, 1999
Last modified: May 14, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families