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Q9X784 (EX7S_MYCLE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Exodeoxyribonuclease 7 small subunit

EC=3.1.11.6
Alternative name(s):
Exodeoxyribonuclease VII small subunit
Short name=Exonuclease VII small subunit
Gene names
Name:xseB
Ordered Locus Names:ML1941
ORF Names:MLCB1222.09
OrganismMycobacterium leprae (strain TN) [Complete proteome] [HAMAP]
Taxonomic identifier272631 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeMycobacteriaceaeMycobacterium

Protein attributes

Sequence length78 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00337

Catalytic activity

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00337

Subunit structure

Heterooligomer composed of large and small subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00337.

Sequence similarities

Belongs to the XseB family.

Sequence caution

The sequence CAB39815.1 differs from that shown. Reason: Erroneous initiation.

The sequence CAC30896.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionExonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

exodeoxyribonuclease VII complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionexodeoxyribonuclease VII activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 7878Exodeoxyribonuclease 7 small subunit HAMAP-Rule MF_00337
PRO_0000206973

Sequences

Sequence LengthMass (Da)Tools
Q9X784 [UniParc].

Last modified April 27, 2001. Version 2.
Checksum: 610D601F32D0725E

FASTA788,865
        10         20         30         40         50         60 
MRSTTPINTT PINQLGYEAC RDELIEVVRL LEQGGLNLDM SLKLWERGEQ LAKRCEEHLD 

        70 
GARQRVADVL SARQVEEA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL049491 Genomic DNA. Translation: CAB39815.1. Different initiation.
AL583923 Genomic DNA. Translation: CAC30896.1. Different initiation.
PIRH87151.
RefSeqNP_302309.1. NC_002677.1.

3D structure databases

ProteinModelPortalQ9X784.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272631.ML1941.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC30896; CAC30896; CAC30896.
GeneID910018.
KEGGmle:ML1941.
PATRIC18057516. VBIMycLep78757_3682.

Organism-specific databases

LepromaML1941.
CMRSearch...

Phylogenomic databases

eggNOGCOG1722.
HOGENOMHOG000228798.
KOK03602.
OrthoDBEOG69KV31.

Family and domain databases

Gene3D1.10.287.1040. 1 hit.
HAMAPMF_00337. Exonuc_7_S.
InterProIPR003761. Exonuc_VII_S.
[Graphical view]
PfamPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
PIRSFPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01280. xseB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEX7S_MYCLE
AccessionPrimary (citable) accession number: Q9X784
Entry history
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: May 14, 2014
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families