Reviewed, UniProtKB/Swiss-Prot Q9X706 (GLND_CORGL)

Names and origin

Protein names

Recommended name:
    [Protein-PII] uridylyltransferase
      Short name=PII uridylyl-transferase
    EC=2.7.7.59
Alternative name(s):
    Uridylyl-removing enzyme
    UTase

Gene names

Name:	glnD
Ordered Locus Names:	Cgl2059, cg2258

Organism

Corynebacterium glutamicum (Brevibacterium flavum) [Complete proteome] [HAMAP]

Taxonomic identifier

1718 [NCBI]

Taxonomic lineage

Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium

Protein attributes

Sequence length	692 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (glnB) regulatory protein By similarity. HAMAP MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP MF_00277
Sequence similarities	Belongs to the glnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 692	692	[Protein-PII] uridylyltransferase HAMAP MF_00277		PRO_0000192730

Sequences

	Sequence		Length	Mass (Da)
	Q9X706-1 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: A7AC19614C133676	FASTA	692	75,970
	10 20 30 40 50 60 MNNPAQLRQD TEKEVLALLG SLVLPAGTAL AATGSLARSE LTPYSDLDLI LIHPPGATPD 70 80 90 100 110 120 GVEDLWYPIW DAKKRLDYSV RTPDECVAMI SADSTAALAM LDLRFVAGDE DLCAKTRRRI 130 140 150 160 170 180 VEKWRQELNK NFDAVVDTAI ARWRRSGPVV AMTRPDLKHG RGGLRDFELI KALALGHLCN 190 200 210 220 230 240 LPQLDAQHQL LLDARTLLHV HARRSRDVLD PEFAVDVAMD LGFVDRYHLG REIADAARAI 250 260 270 280 290 300 DDGLTTALAT ARGILPRRTG FAFRNASRRP LDLDVVDANG TIELSKKPDL NDPALPLRVA 310 320 330 340 350 360 AAAATTGLPV AESTWVRLNE CPPLPEPWPA NAAGDFFRIL SSPKNSRRVV KNMDRHGLWS 370 380 390 400 410 420 RFVPEWDRIK GLMPREPSHI STIDEHSLNT VAGCALETVT VARPDLLVLG ALYHDIGKGF 430 440 450 460 470 480 PRPHEQVGAE MVARAASRMG LNLRDRASVQ TLVAEHTAVA KIAARLDPSS EGAVDKLLDA 490 500 510 520 530 540 VRYDLVTLNL LEVLTEADAK ATGPGVWTAR LEHALRIVCK RARDRLTDIR PVAPMIAPRS 550 560 570 580 590 600 EIGLVERDGV FTVQWHGEDL HRILGVIYAK GWTITAARML ANGQWSAEFD VRANGPQDFD 610 620 630 640 650 660 PQHFLQAYQS GVFSEVPIPA LGITATFWHG NTLEVRTELR TGAIFALLRT LPDALWINAV 670 680 690 TRGATLIIQA ALKPGFDRAT VERSVVRSLA GS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nitrogen regulation in Corynebacterium glutamicum: isolation of genes involved and biochemical characterization of corresponding proteins." Jakoby M.J., Kraemer R., Burkovski A. FEMS Microbiol. Lett. 173:303-310(1999) [PubMed: 10227160] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[2]	"Complete genomic sequence of Corynebacterium glutamicum ATCC 13032." Nakagawa S. Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[3]	"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed: 12948626] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ010319 Genomic DNA. Translation: CAB39374.1. BA000036 Genomic DNA. Translation: BAB99452.1. BX927154 Genomic DNA. Translation: CAF20397.1.
RefSeq	NP_601262.1. YP_226298.1.
3D structure databases
SMR	Q9X706. Positions 24-240.
ModBase	Search...
Genome annotation databases
GeneID	1020013. 3343788.
GenomeReviews	Gene locus Cgl2059 in contig BA000036_GR.
KEGG	cgb:cg2258. cgl:NCgl1981.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG428777.
OMA	DTAIARW.
PhylomeDB	Q9X706.
Enzyme and pathway databases
BioCyc	CGLU196627:CG2258-MONOMER.
BRENDA	2.7.7.59. 812.
Family and domain databases
HAMAP	MF_00277. PII_uridylyl-transf. Divergent sequence. [Tree]
InterPro	IPR010043. GlnD_Uridyltrans. IPR003607. Metal-dep_PHydrolase_HD_dom. IPR006674. Metal-dep_PHydrolase_HD_sub. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. GlnD_Uridyltrans. 1 hit.
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLND_CORGL

Accession

Primary (citable) accession number: Q9X706

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1999
Last modified:	February 9, 2010
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)