Q9X706 (GLND_CORGL) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	Cgl2059, cg2258

Organism

Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [Reference proteome] [HAMAP]

Taxonomic identifier

196627 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Corynebacteriaceae › Corynebacterium › Corynebacterium glutamicum

Protein attributes

Sequence length	692 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	nitrogen compound metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 692	692	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000192730

Sequences

	Sequence		Length	Mass (Da)
	Q9X706 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: A7AC19614C133676	FASTA	692	75,970
	10 20 30 40 50 60 MNNPAQLRQD TEKEVLALLG SLVLPAGTAL AATGSLARSE LTPYSDLDLI LIHPPGATPD 70 80 90 100 110 120 GVEDLWYPIW DAKKRLDYSV RTPDECVAMI SADSTAALAM LDLRFVAGDE DLCAKTRRRI 130 140 150 160 170 180 VEKWRQELNK NFDAVVDTAI ARWRRSGPVV AMTRPDLKHG RGGLRDFELI KALALGHLCN 190 200 210 220 230 240 LPQLDAQHQL LLDARTLLHV HARRSRDVLD PEFAVDVAMD LGFVDRYHLG REIADAARAI 250 260 270 280 290 300 DDGLTTALAT ARGILPRRTG FAFRNASRRP LDLDVVDANG TIELSKKPDL NDPALPLRVA 310 320 330 340 350 360 AAAATTGLPV AESTWVRLNE CPPLPEPWPA NAAGDFFRIL SSPKNSRRVV KNMDRHGLWS 370 380 390 400 410 420 RFVPEWDRIK GLMPREPSHI STIDEHSLNT VAGCALETVT VARPDLLVLG ALYHDIGKGF 430 440 450 460 470 480 PRPHEQVGAE MVARAASRMG LNLRDRASVQ TLVAEHTAVA KIAARLDPSS EGAVDKLLDA 490 500 510 520 530 540 VRYDLVTLNL LEVLTEADAK ATGPGVWTAR LEHALRIVCK RARDRLTDIR PVAPMIAPRS 550 560 570 580 590 600 EIGLVERDGV FTVQWHGEDL HRILGVIYAK GWTITAARML ANGQWSAEFD VRANGPQDFD 610 620 630 640 650 660 PQHFLQAYQS GVFSEVPIPA LGITATFWHG NTLEVRTELR TGAIFALLRT LPDALWINAV 670 680 690 TRGATLIIQA ALKPGFDRAT VERSVVRSLA GS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nitrogen regulation in Corynebacterium glutamicum: isolation of genes involved and biochemical characterization of corresponding proteins." Jakoby M.J., Kraemer R., Burkovski A. FEMS Microbiol. Lett. 173:303-310(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[2]	"The Corynebacterium glutamicum genome: features and impacts on biotechnological processes." Ikeda M., Nakagawa S. Appl. Microbiol. Biotechnol. 62:99-109(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.
[3]	"The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins." Kalinowski J., Bathe B., Bartels D., Bischoff N., Bott M., Burkovski A., Dusch N., Eggeling L., Eikmanns B.J., Gaigalat L., Goesmann A., Hartmann M., Huthmacher K., Kraemer R., Linke B., McHardy A.C., Meyer F., Moeckel B. , Pfefferle W., Puehler A., Rey D.A., Rueckert C., Rupp O., Sahm H., Wendisch V.F., Wiegraebe I., Tauch A. J. Biotechnol. 104:5-25(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ010319 Genomic DNA. Translation: CAB39374.1. BA000036 Genomic DNA. Translation: BAB99452.1. BX927154 Genomic DNA. Translation: CAF20397.1.
RefSeq	NP_601262.1. NC_003450.3. YP_226298.1. NC_006958.1.
3D structure databases
ProteinModelPortal	Q9X706.
ModBase	Search...
Protein-protein interaction databases
STRING	196627.cg2258.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB99452; BAB99452; BAB99452. CAF20397; CAF20397; cg2258.
GeneID	1020013. 3343788.
KEGG	cgb:cg2258. cgl:NCgl1981.
PATRIC	21496122. VBICorGlu203724_1997.
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000021840.
KO	K00990.
OMA	HDIGKGY.
ProtClustDB	PRK00227.
Enzyme and pathway databases
BRENDA	2.7.7.59. 1648.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf. Divergent sequence.
InterPro	IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
SMART	SM00471. HDc. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLND_CORGL

Accession

Primary (citable) accession number: Q9X706

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1999
Last modified:	May 29, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program