pbpA

Functionⁱ

GO - Molecular functionⁱ

penicillin binding Source: InterPro

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Penicillin-binding protein 2Imported Submitted name: Sporulation-specific penicillin-binding proteinImported Submitted name: Stage V sporulation protein DImported
Gene namesⁱ	Name:pbpAImported Synonyms:spoVDImported ORF Names:AO964_03845Imported, AOY09_05445Imported, B0B20_29715Imported, PAERUG_E15_London_28_01_14_04647Imported, PAERUG_P32_London_17_VIM_2_10_11_02137Imported
Organismⁱ	Pseudomonas aeruginosaImported
Taxonomic identifierⁱ	287 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › Pseudomonas aeruginosa group
Proteomesⁱ	UP000189003 Componentⁱ: Unassembled WGS sequence UP000042235 Componentⁱ: Unassembled WGS sequence UP000054840 Componentⁱ: Unassembled WGS sequence

Organism-specific databases

Pseudomonas genome database More...PseudoCAPⁱ	PA4003.

PseudoCAPⁱ

PA4003.

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	21 – 40	HelicalSequence analysisAdd BLAST		20

GO - Cellular componentⁱ

integral component of membrane Source: UniProtKB-KW

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

Pathology & Biotechⁱ

Chemistry databases

ChEMBLⁱ	CHEMBL5539.
Drug and drug target database More...DrugBankⁱ	DB01413. Cefepime. DB00438. Ceftazidime.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	64 – 236	PBP_dimerInterPro annotationAdd BLAST		173
Domainⁱ	268 – 604	TranspeptidaseInterPro annotationAdd BLAST		337

Keywords - Domainⁱ

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGⁱ	ENOG4105CJN. Bacteria. COG0768. LUCA.
HOGENOMⁱ	HOG000266120.
KEGG Orthology (KO) More...KOⁱ	K05515.

Family and domain databases

InterProⁱ	View protein in InterPro IPR012338. Beta-lactam/transpept-like. IPR005311. PBP_dimer. IPR001460. PCN-bd_Tpept. IPR017790. Penicillin-binding_protein_2.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03717. PBP_dimer. 1 hit. PF00905. Transpeptidase. 1 hit.
SUPFAMⁱ	SSF56519. SSF56519. 1 hit. SSF56601. SSF56601. 1 hit.
TIGRFAMsⁱ	TIGR03423. pbp2_mrdA. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q9X6V3-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPQPIHLKDH EKDARLVRRR VIVGAVAVVL LTLVLVARMY HLQVTQYEYH 
        60         70         80         90        100
STLSENNRVH VQPIPPTRGI IFDRNGVIIA DNRPSFSLTI TRERTEDLQK 
       110        120        130        140        150
TLDTLVEILG LTEDDRAIFE KRMKQGRRPF EPVPIMFELN EEQIARIAVN 
       160        170        180        190        200
QFRLPGVDVA TQFVRHYPLK EHFAHSVGYV GRINEQELKN LDPINYSGTH 
       210        220        230        240        250
HIGKTGIERF YESELHGTVG YEEVETNARG RVLRVLKRTD PIPGKDIVLS 
       260        270        280        290        300
IDSRLQEAAE NALAGRRGAI VAIQPSTGDV LAMVSQPSYD PNLFVTGISF 
       310        320        330        340        350
KAYAELRDSI DRPLYNRVLR GLYPPGSTVK PAVALAGLDA GVVTPTSRVF 
       360        370        380        390        400
DPGYYQLPNY DHKYRNWNRY GDGWVSLESA IYRSNDTYFY DLAHKLGIDR 
       410        420        430        440        450
LHAFMSRFGF GQKVALDMFG EADGLMPSRE WKRKTRRQVW YPGETLILGI 
       460        470        480        490        500
GQGYMQATPI QLAQMTALLA NKGHWIRPHL AKTIDGQPPV DPDPMPDIVL 
       510        520        530        540        550
RDPANWDRVD YGMQQVVHGA RGTARKVGAT SAYLIAGKSG TAQVVAIKQN 
       560        570        580        590        600
ERYDRSKLLE RHRDHALFVG FAPANNPQIA VAVMVENGES GSGVAAPVVK 
       610        620        630        640 
QVMDAWLLDE HGKLKAEYAE PVAPLAAAVA KPEPTAAEPE APALEQ

Length:646

Mass (Da):72,213

Last modified:November 1, 1999 - v1

Checksum:ⁱ2F4CA6F5746CCCB1

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF147448 Genomic DNA. Translation: AAD32230.1. CP012901 Genomic DNA. Translation: ALV80466.1. CVVJ01000117 Genomic DNA. Translation: CRO33333.1. CVWF01000185 Genomic DNA. Translation: CRQ64476.1. LLOD01000001 Genomic DNA. Translation: KSH18796.1. MULE01000028 Genomic DNA. Translation: ONM99320.1.
PIRⁱ	G83146.
NCBI Reference Sequences More...RefSeqⁱ	NP_252692.1. NC_002516.2. WP_003093191.1. NZ_NBVZ01000010.1.

Genome annotation databases

EnsemblBacteriaⁱ	CRO33333; CRO33333; PAERUG_P32_London_17_VIM_2_10_11_02137. CRQ64476; CRQ64476; PAERUG_E15_London_28_01_14_04647. KSH18796; KSH18796; AO964_03845.
GeneIDⁱ	878962.
KEGGⁱ	pae:PA4003. paeb:NCGM1900_0960.
PATRICⁱ	fig\|287.1477.peg.1343.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF147448 Genomic DNA. Translation: AAD32230.1. CP012901 Genomic DNA. Translation: ALV80466.1. CVVJ01000117 Genomic DNA. Translation: CRO33333.1. CVWF01000185 Genomic DNA. Translation: CRQ64476.1. LLOD01000001 Genomic DNA. Translation: KSH18796.1. MULE01000028 Genomic DNA. Translation: ONM99320.1.
PIRⁱ	G83146.
NCBI Reference Sequences More...RefSeqⁱ	NP_252692.1. NC_002516.2. WP_003093191.1. NZ_NBVZ01000010.1.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Chemistry databases

ChEMBLⁱ	CHEMBL5539.
Drug and drug target database More...DrugBankⁱ	DB01413. Cefepime. DB00438. Ceftazidime.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	CRO33333; CRO33333; PAERUG_P32_London_17_VIM_2_10_11_02137. CRQ64476; CRQ64476; PAERUG_E15_London_28_01_14_04647. KSH18796; KSH18796; AO964_03845.
GeneIDⁱ	878962.
KEGGⁱ	pae:PA4003. paeb:NCGM1900_0960.
PATRICⁱ	fig\|287.1477.peg.1343.

Organism-specific databases

Pseudomonas genome database More...PseudoCAPⁱ	PA4003.

PseudoCAPⁱ

PA4003.

Phylogenomic databases

eggNOGⁱ	ENOG4105CJN. Bacteria. COG0768. LUCA.
HOGENOMⁱ	HOG000266120.
KEGG Orthology (KO) More...KOⁱ	K05515.

Family and domain databases

InterProⁱ	View protein in InterPro IPR012338. Beta-lactam/transpept-like. IPR005311. PBP_dimer. IPR001460. PCN-bd_Tpept. IPR017790. Penicillin-binding_protein_2.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF03717. PBP_dimer. 1 hit. PF00905. Transpeptidase. 1 hit.
SUPFAMⁱ	SSF56519. SSF56519. 1 hit. SSF56601. SSF56601. 1 hit.
TIGRFAMsⁱ	TIGR03423. pbp2_mrdA. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q9X6V3_PSEAI
Accessionⁱ	Q9X6V3Primary (citable) accession number: Q9X6V3 Secondary accession number(s): Q7DC85
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 1, 1999
	Last sequence update:	November 1, 1999
	Last modified:	July 5, 2017
	This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteomeImported

UniProtKB - Q9X6V3 (Q9X6V3_PSEAI)

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Penicillin-binding protein 2

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Topology

GO - Cellular componentⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Chemistry databases

Family & Domainsⁱ

Domains and Repeats

Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Chemistry databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q9X6V3 (Q9X6V3_PSEAI)

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Penicillin-binding protein 2

pbpA

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Chemistry databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Chemistry databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ