Q9X6R4 (Q9X6R4_AERPU) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: Prolyl endopeptidase EMBL AAD34991.1
Organism	Aeromonas punctata (Aeromonas caviae) EMBL AAD34991.1
Taxonomic identifier	648 [NCBI]
Taxonomic lineage	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Aeromonadales › Aeromonadaceae › Aeromonas

Protein attributes

Sequence length	690 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 3IUQ PDB 3IUR PDB 3IUJ PDB 3IUL PDB 3IVM PDB 3IUN PDB 3IUM PDB 3MUN PDB 3MUO
Gene Ontology (GO)
Biological_process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular_function	serine-type endopeptidase activity Inferred from electronic annotation. Source: InterPro serine-type exopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Binding site	679	1	Sucrose PDB 3MUO

Sequences

	Sequence		Length	Mass (Da)
	Q9X6R4 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: E9D1FEDC2986960D	FASTA	690	76,637
	10 20 30 40 50 60 MSGKARLHYP VTRQGEQVDH YFGQAVADPY RWLEDDRSPE TEAWVKAQNA VTQDYLAQIP 70 80 90 100 110 120 YRAAIKEKLA ASWNYAKEGA PFREGRYHYF FKNDGLQNQN VLWRQKEGKP AEVFLDPNTL 130 140 150 160 170 180 SPDGTTALDQ LSFSRDGRIL AYSLSLAGSD WREIHLMDVE SKQPLETPLK DVKFSGISWL 190 200 210 220 230 240 GNEGFFYSSY DKPDGSELSA RTDQHKVYFH RLGTAQEDDR LVFGAIPAQH HRYVGATVTE 250 260 270 280 290 300 DDRFLLISAA NSTSGNRLYV KDLSQENAPL LTVQGDLDAD VSLVDNKGST LYLLTNRDAP 310 320 330 340 350 360 NRRLVTVDAA NPGPAHWRDL IPERHRVLTV HSGTAYLFAE YMVDATAPVE QFDYEGKRVR 370 380 390 400 410 420 EVALPGLGSV SGFNGKHDDP ALYFGFENYA QPPTLYRFEP KSGAISLYRA SAAPFKPEDY 430 440 450 460 470 480 VSEQRFYQSK DGTRVPLIIS YRKGLKLDGS NPTILYGYGG FDVSLTPSFS VSVANWLDLG 490 500 510 520 530 540 GVYAVANLRG GGEYGQAWHL AGTQQNKQNV FDDFIAAAEY LKAEGYTRTD RLAIRGGSNG 550 560 570 580 590 600 GLLVGAVMTQ RPDLMRVALP AVGVLDMLRY HTFTAGAGWA YDYGTSADSE AMFDYLKGYS 610 620 630 640 650 660 PLHNVRPGVS YPSTMVTTAD HDDRVVPAHS FKFAATLQAD NAGPHPQLIR IETNAGHGAG 670 680 690 TPVAKLIEQS ADIYAFTLYE MGYRELPRQP

References

[1]	"Prolyl endopeptidase from Aeromonas punctata." Li M., Xu H., Chen C. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Induced-fit mechanism for prolyl endopeptidase." Li M., Chen C., Davies D.R., Chiu T.K. J. Biol. Chem. 285:21487-21495(2010) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
[3]	"Route of Substrate Entry in Prolyl Endopeptidase." Chiu T.K., Li M. Submitted (MAY-2010) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF143951 Genomic DNA. Translation: AAD34991.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IUJ	X-ray	1.80	A	1-690	[»]
3IUL	X-ray	1.95	A	1-690	[»]
3IUM	X-ray	2.25	A	1-690	[»]
3IUN	X-ray	2.40	A	1-690	[»]
3IUQ	X-ray	2.10	A	1-690	[»]
3IUR	X-ray	2.05	A	1-690	[»]
3IVM	X-ray	2.05	A	1-690	[»]
3MUN	X-ray	2.10	A	1-690	[»]
3MUO	X-ray	1.95	A	1-690	[»]

ProteinModelPortal

Q9X6R4.

ModBase

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Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

Gene3D

2.130.10.120. 1 hit.

InterPro

IPR002471. Pept_S9_AS.
IPR023302. Pept_S9A_oligopept_N.
IPR001375. Peptidase_S9.
IPR002470. Peptidase_S9A.
IPR004106. Peptidase_S9A_B_C_N.
[Graphical view]

PANTHER

PTHR11757. PTHR11757. 1 hit.

Pfam

PF00326. Peptidase_S9. 1 hit.
PF02897. Peptidase_S9_N. 1 hit.
[Graphical view]

PRINTS

PR00862. PROLIGOPTASE.

SUPFAM

SSF50993. Peptidase_S9A_N. 1 hit.

PROSITE

PS00708. PRO_ENDOPEP_SER. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q9X6R4.

Entry information

Entry name

Q9X6R4_AERPU

Accession

Primary (citable) accession number: Q9X6R4

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	March 6, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)