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Protein

Elongation factor Ts

Gene

tsf

Organism
Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Ts
Short name:
EF-Ts
Gene namesi
Name:tsf
Ordered Locus Names:CBU_1385
OrganismiCoxiella burnetii (strain RSA 493 / Nine Mile phase I)
Taxonomic identifieri227377 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaLegionellalesCoxiellaceaeCoxiella
Proteomesi
  • UP000002671 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001611131 – 296Elongation factor TsAdd BLAST296

Proteomic databases

PRIDEiQ9X5U9.

Expressioni

Developmental stagei

Up-regulated more than 4 fold in the large cell variant (LCV) stage compared to the small cell variant (SCV) stage; at protein level. LCVs are thought to be more metabolically active than SCVs.

Interactioni

Protein-protein interaction databases

STRINGi227377.CBU_1385.

Structurei

3D structure databases

ProteinModelPortaliQ9X5U9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni82 – 85Involved in Mg(2+) ion dislocation from EF-TuBy similarity4

Sequence similaritiesi

Belongs to the EF-Ts family.Curated

Phylogenomic databases

eggNOGiENOG4105CU7. Bacteria.
COG0264. LUCA.
HOGENOMiHOG000220987.
KOiK02357.
OMAiDAGMMDC.

Family and domain databases

Gene3Di3.30.479.20. 2 hits.
HAMAPiMF_00050. EF_Ts. 1 hit.
InterProiView protein in InterPro
IPR036402. EF-Ts_dimer_sf.
IPR001816. Transl_elong_EFTs/EF1B.
IPR014039. Transl_elong_EFTs/EF1B_dimer.
IPR018101. Transl_elong_Ts_CS.
IPR009060. UBA-like_sf.
PANTHERiPTHR11741. PTHR11741. 1 hit.
PfamiView protein in Pfam
PF00889. EF_TS. 1 hit.
SUPFAMiSSF46934. SSF46934. 1 hit.
SSF54713. SSF54713. 2 hits.
TIGRFAMsiTIGR00116. tsf. 1 hit.
PROSITEiView protein in PROSITE
PS01126. EF_TS_1. 1 hit.
PS01127. EF_TS_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9X5U9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTITPIMVK ELRERTGAAV MACKKALQET NGDMEAAIDL LRKAGDAKAA
60 70 80 90 100
KRAGKTAAEG VIVIAISKDQ KKGFMAEVNS ETDFVARDTN FMAFASKVAE
110 120 130 140 150
RGLAEGVSDV AATLALPIEP NSSSTIEDER KALVNRIGEN IQIRRVASLS
160 170 180 190 200
SDGVVGHYSH GGRIGVLLAL DVPNPELAKG LAMHVAAFNP QAVSANQVST
210 220 230 240 250
EFVEKEKEIF LARAQETGKP ANIIEKMVKG QVEKLLKEVS LEGQSFVKDP
260 270 280 290
EKLVGDLLKA EKAKVLAFLR FEVGEGVEKE SQNFADEVMA QVQGNR
Length:296
Mass (Da):31,820
Last modified:November 1, 1999 - v1
Checksum:i52FB20668DED665A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF127534 Genomic DNA. Translation: AAD33343.1.
AE016828 Genomic DNA. Translation: AAO90888.1.
RefSeqiNP_820374.1. NC_002971.3.
WP_005772548.1. NZ_CDBG01000001.1.

Genome annotation databases

EnsemblBacteriaiAAO90888; AAO90888; CBU_1385.
GeneIDi1209291.
31483244.
KEGGicbu:CBU_1385.
PATRICifig|227377.7.peg.1381.

Similar proteinsi

Entry informationi

Entry nameiEFTS_COXBU
AccessioniPrimary (citable) accession number: Q9X5U9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: November 22, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Coxiella burnetii
    Coxiella burnetii (strain RSA 493): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families