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Q9X4E3

- TRPF_RHOS4

UniProt

Q9X4E3 - TRPF_RHOS4

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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciRSPH272943:GJAS-3716-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:RHOS4_36220
ORF Names:RSP_3587
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
ProteomesiUP000002703: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 212212N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154375Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272943.RSP_3587.

Structurei

3D structure databases

ProteinModelPortaliQ9X4E3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.
PhylomeDBiQ9X4E3.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9X4E3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAGVRVKICG LRTESDVKAA ASSGAAYVGL VFFPKSPRHL ELAQAQRLAL
60 70 80 90 100
AAPPGVAKVA LTVDASDETL DAIVEAVPLD MLQLHGGESP ERVAEVRARY
110 120 130 140 150
GLPVMKAVGV ADEGDLPQIL EQSLAADQIL IDAKPPKGAA LPGGNGLSFD
160 170 180 190 200
WRLISGRHWI RPWMLAGGLT VENLAEAVRR TGASQVDVSS GVESAPGVKD
210
PARIAAFLQA AR
Length:212
Mass (Da):22,142
Last modified:November 1, 1999 - v1
Checksum:iDF2D9294D0D8ACAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF107093 Genomic DNA. Translation: AAD29259.1.
CP000144 Genomic DNA. Translation: ABA81190.1.
RefSeqiWP_011339435.1. NZ_AKVW01000002.1.
YP_355091.1. NC_007494.2.

Genome annotation databases

EnsemblBacteriaiABA81190; ABA81190; RSP_3587.
GeneIDi3722104.
KEGGirsp:RSP_3587.
PATRICi23157357. VBIRhoSph57909_4023.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF107093 Genomic DNA. Translation: AAD29259.1 .
CP000144 Genomic DNA. Translation: ABA81190.1 .
RefSeqi WP_011339435.1. NZ_AKVW01000002.1.
YP_355091.1. NC_007494.2.

3D structure databases

ProteinModelPortali Q9X4E3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 272943.RSP_3587.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA81190 ; ABA81190 ; RSP_3587 .
GeneIDi 3722104.
KEGGi rsp:RSP_3587.
PATRICi 23157357. VBIRhoSph57909_4023.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi DILQLHG.
OrthoDBi EOG6N94DF.
PhylomeDBi Q9X4E3.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci RSPH272943:GJAS-3716-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Multiple chromosomes in bacteria. The yin and yang of trp gene localization in Rhodobacter sphaeroides 2.4.1."
    Mackenzie C., Simmons A.E., Kaplan S.
    Genetics 153:525-538(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequence of chromosome 2 of Rhodobacter sphaeroides 2.4.1."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Entry informationi

Entry nameiTRPF_RHOS4
AccessioniPrimary (citable) accession number: Q9X4E3
Secondary accession number(s): Q3IW94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: October 1, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3