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Protein

N-(5'-phosphoribosyl)anthranilate isomerase

Gene

trpF

Organism
Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.

Pathwayi

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciRSPH272943:GJAS-3716-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:RHOS4_36220
ORF Names:RSP_3587
OrganismiRhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
Taxonomic identifieri272943 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
ProteomesiUP000002703 Componenti: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 212212N-(5'-phosphoribosyl)anthranilate isomerasePRO_0000154375Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi272943.RSP_3587.

Structurei

3D structure databases

ProteinModelPortaliQ9X4E3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.Curated

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.
PhylomeDBiQ9X4E3.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9X4E3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVRVKICG LRTESDVKAA ASSGAAYVGL VFFPKSPRHL ELAQAQRLAL
60 70 80 90 100
AAPPGVAKVA LTVDASDETL DAIVEAVPLD MLQLHGGESP ERVAEVRARY
110 120 130 140 150
GLPVMKAVGV ADEGDLPQIL EQSLAADQIL IDAKPPKGAA LPGGNGLSFD
160 170 180 190 200
WRLISGRHWI RPWMLAGGLT VENLAEAVRR TGASQVDVSS GVESAPGVKD
210
PARIAAFLQA AR
Length:212
Mass (Da):22,142
Last modified:November 1, 1999 - v1
Checksum:iDF2D9294D0D8ACAC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF107093 Genomic DNA. Translation: AAD29259.1.
CP000144 Genomic DNA. Translation: ABA81190.1.
RefSeqiWP_011339435.1. NZ_AKVW01000002.1.
YP_355091.1. NC_007494.2.

Genome annotation databases

EnsemblBacteriaiABA81190; ABA81190; RSP_3587.
GeneIDi3722104.
KEGGirsp:RSP_3587.
PATRICi23157357. VBIRhoSph57909_4023.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF107093 Genomic DNA. Translation: AAD29259.1.
CP000144 Genomic DNA. Translation: ABA81190.1.
RefSeqiWP_011339435.1. NZ_AKVW01000002.1.
YP_355091.1. NC_007494.2.

3D structure databases

ProteinModelPortaliQ9X4E3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272943.RSP_3587.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA81190; ABA81190; RSP_3587.
GeneIDi3722104.
KEGGirsp:RSP_3587.
PATRICi23157357. VBIRhoSph57909_4023.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiDILQLHG.
OrthoDBiEOG6N94DF.
PhylomeDBiQ9X4E3.

Enzyme and pathway databases

UniPathwayiUPA00035; UER00042.
BioCyciRSPH272943:GJAS-3716-MONOMER.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Multiple chromosomes in bacteria. The yin and yang of trp gene localization in Rhodobacter sphaeroides 2.4.1."
    Mackenzie C., Simmons A.E., Kaplan S.
    Genetics 153:525-538(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Complete sequence of chromosome 2 of Rhodobacter sphaeroides 2.4.1."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Richardson P., Mackenzie C., Choudhary M., Larimer F., Hauser L.J., Land M., Donohue T.J., Kaplan S.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158.

Entry informationi

Entry nameiTRPF_RHOS4
AccessioniPrimary (citable) accession number: Q9X4E3
Secondary accession number(s): Q3IW94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: May 27, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.