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Protein

Thioredoxin

Gene

trxA

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processElectron transport, Transport

Enzyme and pathway databases

BioCyciPAER208964:G1FZ6-5360-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Thioredoxin
Short name:
Trx
Gene namesi
Name:trxA
Synonyms:trx
Ordered Locus Names:PA5240
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA5240

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001201201 – 108ThioredoxinAdd BLAST108

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi33 ↔ 36Redox-activePROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ9X2T1

Interactioni

Protein-protein interaction databases

STRINGi208964.PA5240

Structurei

3D structure databases

ProteinModelPortaliQ9X2T1
SMRiQ9X2T1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini2 – 108ThioredoxinPROSITE-ProRule annotationAdd BLAST107

Sequence similaritiesi

Belongs to the thioredoxin family.Curated

Keywords - Domaini

Redox-active center

Phylogenomic databases

eggNOGiENOG4105K63 Bacteria
COG0526 LUCA
HOGENOMiHOG000292977
InParanoidiQ9X2T1
KOiK03671
OMAiDANQEFA
PhylomeDBiQ9X2T1

Family and domain databases

InterProiView protein in InterPro
IPR005746 Thioredoxin
IPR036249 Thioredoxin-like_sf
IPR017937 Thioredoxin_CS
IPR013766 Thioredoxin_domain
PANTHERiPTHR10438 PTHR10438, 1 hit
PfamiView protein in Pfam
PF00085 Thioredoxin, 1 hit
PIRSFiPIRSF000077 Thioredoxin, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit
TIGRFAMsiTIGR01068 thioredoxin, 1 hit
PROSITEiView protein in PROSITE
PS00194 THIOREDOXIN_1, 1 hit
PS51352 THIOREDOXIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9X2T1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEHIVNVTD ASFEQDVLKA DGPVLVDYWA EWCGPCKMIA PVLDEVARDY
60 70 80 90 100
QGKLKVCKLN IDENQDTPPK YGVRGIPTLM LFKDGNVEAT KVGALSKSQL

AAFLDANI
Length:108
Mass (Da):11,870
Last modified:November 1, 1999 - v1
Checksum:i908A6E87385C6AD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF053463 Genomic DNA Translation: AAD29108.2
AE004091 Genomic DNA Translation: AAG08625.1
PIRiG82991
RefSeqiNP_253927.1, NC_002516.2
WP_003096336.1, NC_002516.2

Genome annotation databases

EnsemblBacteriaiAAG08625; AAG08625; PA5240
GeneIDi877946
KEGGipae:PA5240
PATRICifig|208964.12.peg.5492

Similar proteinsi

Entry informationi

Entry nameiTHIO_PSEAE
AccessioniPrimary (citable) accession number: Q9X2T1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: November 1, 1999
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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