Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q9X2N2 (6PGL_PSEAE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
6-phosphogluconolactonase
Short name=6PGL
EC=3.1.1.31
Gene names
Name:pgl
Synonyms:devB
Ordered Locus Names:PA3182
OrganismPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifier208964 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.

Sequence similarities

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Sequence caution

The sequence AAD22666.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2382386-phosphogluconolactonase
PRO_0000090102

Sequences

Sequence LengthMass (Da)Tools
Q9X2N2 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: EECE335BBE904F46

FASTA23825,571
        10         20         30         40         50         60 
MAISELKLPA GVGLQVWGSA AEQARGLAAE VAGRLRSALA EQGQALLVVS GGRSPVAFLE 

        70         80         90        100        110        120 
ALSEEPLDWS RITVSLADER WVPESHADSN AGLVRRHLLR GEAAKARFIG LYQPAASLEE 

       130        140        150        160        170        180 
AAELADHHLH ELPLPIDVLV LGMGDDGHTA SLFPNSPGLD LAMDPQGTRR CLPMWAPSVP 

       190        200        210        220        230 
HQRLTLPRAV LAAAKVQLLA IQGQSKLATL NAALAVEDER RMPVRAFLRA PLTIHWYP

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AF029673 Genomic DNA. Translation: AAD22666.1. Different initiation.
AE004091 Genomic DNA. Translation: AAG06570.1.
PIRH83247.
RefSeqNP_251872.1. NC_002516.2.

3D structure databases

ProteinModelPortalQ9X2N2.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID882680.
GenomeReviewsGene locus PA3182 in contig AE004091_GR.
KEGGpae:PA3182.
NMPDRfig|208964.1.peg.3182.
PATRIC19840931. VBIPseAer58763_3326.

Organism-specific databases

PseudoCAPPA3182.

Phylogenomic databases

HOGENOMHBG725991.
OMARWVPETS.
ProtClustDBCLSK867798.

Enzyme and pathway databases

BioCycPAER208964:PA3182-MONOMER.
BRENDA3.1.1.31. 5087.

Family and domain databases

InterProIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
KOK01057.
PfamPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsTIGR01198. Pgl. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL_PSEAE
AccessionPrimary (citable) accession number: Q9X2N2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: January 25, 2012
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents