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Protein

Probable butyrate kinase 2

Gene

buk2

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + butanoate = ADP + butanoyl phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.2.7. 6331.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable butyrate kinase 2UniRule annotation (EC:2.7.2.7UniRule annotation)
Short name:
BK 2UniRule annotation
Alternative name(s):
Branched-chain carboxylic acid kinase 2UniRule annotation
Gene namesi
Name:buk2UniRule annotation
Ordered Locus Names:TM_1756
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 375375Probable butyrate kinase 2PRO_0000107675Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243274.TM1756.

Structurei

Secondary structure

1
375
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 97Combined sources
Beta strandi11 – 2010Combined sources
Beta strandi23 – 319Combined sources
Helixi34 – 385Combined sources
Helixi43 – 464Combined sources
Helixi47 – 5913Combined sources
Turni60 – 623Combined sources
Helixi65 – 673Combined sources
Beta strandi69 – 746Combined sources
Beta strandi83 – 875Combined sources
Helixi90 – 989Combined sources
Turni99 – 1013Combined sources
Helixi107 – 12014Combined sources
Beta strandi124 – 1285Combined sources
Helixi137 – 1393Combined sources
Beta strandi143 – 1464Combined sources
Helixi155 – 16814Combined sources
Helixi173 – 1753Combined sources
Beta strandi177 – 19317Combined sources
Beta strandi196 – 2005Combined sources
Helixi203 – 2053Combined sources
Helixi220 – 2278Combined sources
Helixi236 – 2383Combined sources
Turni240 – 2434Combined sources
Helixi247 – 2515Combined sources
Helixi256 – 2649Combined sources
Helixi268 – 29124Combined sources
Turni292 – 2943Combined sources
Beta strandi297 – 3037Combined sources
Helixi304 – 3074Combined sources
Turni309 – 3113Combined sources
Helixi312 – 3209Combined sources
Turni321 – 3233Combined sources
Beta strandi326 – 3316Combined sources
Helixi334 – 34613Combined sources
Helixi355 – 36915Combined sources
Helixi371 – 3733Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SAZX-ray2.50A1-375[»]
1X9JX-ray3.00A/B/C/D/E/F/G/H1-375[»]
ProteinModelPortaliQ9X278.
SMRiQ9X278. Positions 1-375.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9X278.

Family & Domainsi

Sequence similaritiesi

Belongs to the acetokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CKM. Bacteria.
COG3426. LUCA.
InParanoidiQ9X278.
KOiK00929.
OMAiFRILTIN.
OrthoDBiEOG6KHG1Q.

Family and domain databases

HAMAPiMF_00542. Butyrate_kinase.
InterProiIPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
IPR011245. Butyrate_kin.
[Graphical view]
PANTHERiPTHR21060. PTHR21060. 1 hit.
PTHR21060:SF3. PTHR21060:SF3. 1 hit.
PfamiPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF036458. Butyrate_kin. 1 hit.
PRINTSiPR00471. ACETATEKNASE.
TIGRFAMsiTIGR02707. butyr_kinase. 1 hit.
PROSITEiPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X278-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRILTINPG STSTKLSIFE DERMVKMQNF SHSPDELGRF QKILDQLEFR
60 70 80 90 100
EKIARQFVEE TGYSLSSFSA FVSRGGLLDP IPGGVYLVDG LMIKTLKSGK
110 120 130 140 150
NGEHASNLGA IIAHRFSSET GVPAYVVDPV VVDEMEDVAR VSGHPNYQRK
160 170 180 190 200
SIFHALNQKT VAKEVARMMN KRYEEMNLVV AHMGGGISIA AHRKGRVIDV
210 220 230 240 250
NNALDGDGPF TPERSGTLPL TQLVDLCFSG KFTYEEMKKR IVGNGGLVAY
260 270 280 290 300
LGTSDAREVV RRIKQGDEWA KRVYRAMAYQ IAKWIGKMAA VLKGEVDFIV
310 320 330 340 350
LTGGLAHEKE FLVPWITKRV SFIAPVLVFP GSNEEKALAL SALRVLRGEE
360 370
KPKNYSEESR RWRERYDSYL DGILR
Length:375
Mass (Da):42,022
Last modified:November 1, 1999 - v1
Checksum:iE42C4887071D008D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36821.1.
PIRiE72214.
RefSeqiNP_229554.1. NC_000853.1.
WP_004082291.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD36821; AAD36821; TM_1756.
GeneIDi897722.
KEGGitma:TM1756.
PATRICi23938488. VBITheMar51294_1774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36821.1.
PIRiE72214.
RefSeqiNP_229554.1. NC_000853.1.
WP_004082291.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1SAZX-ray2.50A1-375[»]
1X9JX-ray3.00A/B/C/D/E/F/G/H1-375[»]
ProteinModelPortaliQ9X278.
SMRiQ9X278. Positions 1-375.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM1756.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD36821; AAD36821; TM_1756.
GeneIDi897722.
KEGGitma:TM1756.
PATRICi23938488. VBITheMar51294_1774.

Phylogenomic databases

eggNOGiENOG4105CKM. Bacteria.
COG3426. LUCA.
InParanoidiQ9X278.
KOiK00929.
OMAiFRILTIN.
OrthoDBiEOG6KHG1Q.

Enzyme and pathway databases

BRENDAi2.7.2.7. 6331.

Miscellaneous databases

EvolutionaryTraceiQ9X278.

Family and domain databases

HAMAPiMF_00542. Butyrate_kinase.
InterProiIPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
IPR011245. Butyrate_kin.
[Graphical view]
PANTHERiPTHR21060. PTHR21060. 1 hit.
PTHR21060:SF3. PTHR21060:SF3. 1 hit.
PfamiPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF036458. Butyrate_kin. 1 hit.
PRINTSiPR00471. ACETATEKNASE.
TIGRFAMsiTIGR02707. butyr_kinase. 1 hit.
PROSITEiPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Entry informationi

Entry nameiBUK2_THEMA
AccessioniPrimary (citable) accession number: Q9X278
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: April 13, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.