Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Probable butyrate kinase 2

Gene

buk2

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + butanoate = ADP + butanoyl phosphate.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.2.7. 6331.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable butyrate kinase 2UniRule annotation (EC:2.7.2.7UniRule annotation)
Short name:
BK 2UniRule annotation
Alternative name(s):
Branched-chain carboxylic acid kinase 2UniRule annotation
Gene namesi
Name:buk2UniRule annotation
Ordered Locus Names:TM_1756
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001076751 – 375Probable butyrate kinase 2Add BLAST375

Interactioni

Protein-protein interaction databases

STRINGi243274.TM1756.

Structurei

Secondary structure

1375
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi3 – 9Combined sources7
Beta strandi11 – 20Combined sources10
Beta strandi23 – 31Combined sources9
Helixi34 – 38Combined sources5
Helixi43 – 46Combined sources4
Helixi47 – 59Combined sources13
Turni60 – 62Combined sources3
Helixi65 – 67Combined sources3
Beta strandi69 – 74Combined sources6
Beta strandi83 – 87Combined sources5
Helixi90 – 98Combined sources9
Turni99 – 101Combined sources3
Helixi107 – 120Combined sources14
Beta strandi124 – 128Combined sources5
Helixi137 – 139Combined sources3
Beta strandi143 – 146Combined sources4
Helixi155 – 168Combined sources14
Helixi173 – 175Combined sources3
Beta strandi177 – 193Combined sources17
Beta strandi196 – 200Combined sources5
Helixi203 – 205Combined sources3
Helixi220 – 227Combined sources8
Helixi236 – 238Combined sources3
Turni240 – 243Combined sources4
Helixi247 – 251Combined sources5
Helixi256 – 264Combined sources9
Helixi268 – 291Combined sources24
Turni292 – 294Combined sources3
Beta strandi297 – 303Combined sources7
Helixi304 – 307Combined sources4
Turni309 – 311Combined sources3
Helixi312 – 320Combined sources9
Turni321 – 323Combined sources3
Beta strandi326 – 331Combined sources6
Helixi334 – 346Combined sources13
Helixi355 – 369Combined sources15
Helixi371 – 373Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1SAZX-ray2.50A1-375[»]
1X9JX-ray3.00A/B/C/D/E/F/G/H1-375[»]
ProteinModelPortaliQ9X278.
SMRiQ9X278.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9X278.

Family & Domainsi

Sequence similaritiesi

Belongs to the acetokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CKM. Bacteria.
COG3426. LUCA.
InParanoidiQ9X278.
KOiK00929.
OMAiFRILTIN.

Family and domain databases

HAMAPiMF_00542. Butyrate_kinase. 1 hit.
InterProiIPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
IPR011245. Butyrate_kin.
[Graphical view]
PANTHERiPTHR21060. PTHR21060. 1 hit.
PTHR21060:SF3. PTHR21060:SF3. 1 hit.
PfamiPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF036458. Butyrate_kin. 1 hit.
PRINTSiPR00471. ACETATEKNASE.
TIGRFAMsiTIGR02707. butyr_kinase. 1 hit.
PROSITEiPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X278-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFRILTINPG STSTKLSIFE DERMVKMQNF SHSPDELGRF QKILDQLEFR
60 70 80 90 100
EKIARQFVEE TGYSLSSFSA FVSRGGLLDP IPGGVYLVDG LMIKTLKSGK
110 120 130 140 150
NGEHASNLGA IIAHRFSSET GVPAYVVDPV VVDEMEDVAR VSGHPNYQRK
160 170 180 190 200
SIFHALNQKT VAKEVARMMN KRYEEMNLVV AHMGGGISIA AHRKGRVIDV
210 220 230 240 250
NNALDGDGPF TPERSGTLPL TQLVDLCFSG KFTYEEMKKR IVGNGGLVAY
260 270 280 290 300
LGTSDAREVV RRIKQGDEWA KRVYRAMAYQ IAKWIGKMAA VLKGEVDFIV
310 320 330 340 350
LTGGLAHEKE FLVPWITKRV SFIAPVLVFP GSNEEKALAL SALRVLRGEE
360 370
KPKNYSEESR RWRERYDSYL DGILR
Length:375
Mass (Da):42,022
Last modified:November 1, 1999 - v1
Checksum:iE42C4887071D008D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36821.1.
PIRiE72214.
RefSeqiNP_229554.1. NC_000853.1.
WP_004082291.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD36821; AAD36821; TM_1756.
GeneIDi897722.
KEGGitma:TM1756.
PATRICi23938488. VBITheMar51294_1774.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36821.1.
PIRiE72214.
RefSeqiNP_229554.1. NC_000853.1.
WP_004082291.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1SAZX-ray2.50A1-375[»]
1X9JX-ray3.00A/B/C/D/E/F/G/H1-375[»]
ProteinModelPortaliQ9X278.
SMRiQ9X278.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM1756.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD36821; AAD36821; TM_1756.
GeneIDi897722.
KEGGitma:TM1756.
PATRICi23938488. VBITheMar51294_1774.

Phylogenomic databases

eggNOGiENOG4105CKM. Bacteria.
COG3426. LUCA.
InParanoidiQ9X278.
KOiK00929.
OMAiFRILTIN.

Enzyme and pathway databases

BRENDAi2.7.2.7. 6331.

Miscellaneous databases

EvolutionaryTraceiQ9X278.

Family and domain databases

HAMAPiMF_00542. Butyrate_kinase. 1 hit.
InterProiIPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
IPR011245. Butyrate_kin.
[Graphical view]
PANTHERiPTHR21060. PTHR21060. 1 hit.
PTHR21060:SF3. PTHR21060:SF3. 1 hit.
PfamiPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFiPIRSF036458. Butyrate_kin. 1 hit.
PRINTSiPR00471. ACETATEKNASE.
TIGRFAMsiTIGR02707. butyr_kinase. 1 hit.
PROSITEiPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBUK2_THEMA
AccessioniPrimary (citable) accession number: Q9X278
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: November 2, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.