Q9X1V5 (Q9X1V5_THEMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL AAD36687.1

Gene names

Ordered Locus Names:

TM_1620

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity By similarity. SAAS SAAS004675
Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. SAAS SAAS004675

Ontologies

Keywords
Domain	Redox-active center SAAS SAAS004675
Molecular function	Antioxidant SAAS SAAS004675 Oxidoreductase Peroxidase SAAS SAAS004675
PTM	Disulfide bond SAAS SAAS004675
Technical term	3D-structure PDB 1VKE PDB 1P8C Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	peroxidase activity Inferred from electronic annotation. Source: UniProtKB-KW peroxiredoxin activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9X1V5 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 256A16A2F49A4548	FASTA	121	13,789
	10 20 30 40 50 60 MEYKKFVEAR RELNEKVLSR GTLNTKRFFN LDSAVYRPGK LDVKTKELMG LVASTVLRCD 70 80 90 100 110 120 DCIRYHLVRC VQEGASDEEI FEALDIALVV GGSIVIPHLR RAVGFLEELR EMEKNGETIS L

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of carboxymuconolactone decarboxylase family protein possibly involved in antioxidative response (TM1620) from Thermotoga maritima at 1.56 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (MAY-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.56 ANGSTROMS).
[3]	"Crystal Structure Analysis of Thermotoga maritima protein TM1620 (APC4843)." Kim Y., Joachimiak A., Brunzelle J.S., Korolev S.V., Edwards A., Xu X., Savchenko A. Submitted (MAY-2003) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD36687.1.

PIR

F72232.

RefSeq

NP_229420.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1P8C	X-ray	2.30	A/B/C/D/E/F	1-121	[»]
1VKE	X-ray	1.56	A/B/C/D/E/F	1-121	[»]

ProteinModelPortal

Q9X1V5.

SMR

Q9X1V5. Positions 2-120.

ModBase

Search...

Protein family/group databases

PeroxiBase

4560. TmaCMD.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

897931.

GenomeReviews

Gene locus TM_1620 in contig AE000512_GR.

KEGG

tma:TM1620.

NMPDR

fig|243274.1.peg.1604.

PATRIC

23938214. VBITheMar51294_1639.

TIGR

TM_1620.

Phylogenomic databases

HOGENOM

HBG733727.

OMA

LNTKRFF.

ProtClustDB

CLSK2517525.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_1620-MONOMER.

Family and domain databases

InterPro

IPR004675. AhpD_core.
IPR003779. CMD.
[Graphical view]

Pfam

PF02627. CMD. 1 hit.
[Graphical view]

TIGRFAMs

TIGR00778. AhpD_dom. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q9X1V5_THEMA

Accession

Primary (citable) accession number: Q9X1V5

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)