Q9X1S1 (Q9X1S1_THEMA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glycerate kinase, putative EMBL AAD36652.1

Submitted name:
Hydroxypyruvate reductase EMBL EHA59682.1
EC=1.1.1.81 EMBL EHA59682.1

Gene names

Ordered Locus Names:	TM_1585
ORF Names:	ThemaDRAFT_1115 EMBL EHA59682.1

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP]

Taxonomic identifier

243274 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Thermotogae › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga › Thermotoga maritima

Protein attributes

Sequence length	417 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Pyruvate EMBL EHA59682.1
Molecular function	Kinase EMBL AAD36652.1 Oxidoreductase EMBL EHA59682.1 Transferase
Technical term	3D-structure PDB 2B8N Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	hydroxypyruvate reductase activity Inferred from electronic annotation. Source: EC kinase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9X1S1 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: FEE01EC89CC8E445	FASTA	417	44,722
	10 20 30 40 50 60 MFDPESLKKL AIEIVKKSIE AVFPDRAVKE TLPKLNLDRV ILVAVGKAAW RMAKAAYEVL 70 80 90 100 110 120 GKKIRKGVVV TKYGHSEGPI DDFEIYEAGH PVPDENTIKT TRRVLELVDQ LNENDTVLFL 130 140 150 160 170 180 LSGGGSSLFE LPLEGVSLEE IQKLTSALLK SGASIEEINT VRKHLSQVKG GRFAERVFPA 190 200 210 220 230 240 KVVALVLSDV LGDRLDVIAS GPAWPDSSTS EDALKVLEKY GIETSESVKR AILQETPKHL 250 260 270 280 290 300 SNVEIHLIGN VQKVCDEAKS LAKEKGFNAE IITTSLDCEA REAGRFIASI MKEVKFKDRP 310 320 330 340 350 360 LKKPAALIFG GETVVHVKGN GIGGRNQELA LSAAIALEGI EGVILCSAGT DGTDGPTDAA 370 380 390 400 410 GGIVDGSTAK TLKAMGEDPY QYLKNNDSYN ALKKSGALLI TGPTGTNVND LIIGLIV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of a glycerate kinase (TM1585) from Thermotoga maritima at 2.70 A resolution reveals a new fold." Schwarzenbacher R., McMullan D., Krishna S.S., Xu Q., Miller M.D., Canaves J.M., Elsliger M.A., Floyd R., Grzechnik S.K., Jaroszewski L., Klock H.E., Koesema E., Kovarik J.S., Kreusch A., Kuhn P., McPhillips T.M., Morse A.T., Quijano K. , Spraggon G., Stevens R.C., van den Bedem H., Wolf G., Hodgson K.O., Wooley J., Deacon A.M., Godzik A., Lesley S.A., Wilson I.A. Proteins 65:243-248(2006) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.53 ANGSTROMS).
[3]	"The draft genome of Thermotoga maritima MSB8." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Land M.L., Hauser L., Boucher N., Noll K., Woyke T. Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MSB8 EMBL EHA59682.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD36652.1.
AGIJ01000002 Genomic DNA. Translation: EHA59682.1.

PIR

A72236.

RefSeq

NP_229385.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2B8N	X-ray	2.53	A/B	1-417	[»]

SMR

Q9X1S1. Positions 4-417.

ModBase

Search...

Protein-protein interaction databases

STRING

243274.TM1585.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAD36652; AAD36652; TM_1585.
EHA59682; EHA59682; ThemaDRAFT_1115.

GeneID

897953.

KEGG

tma:TM1585.

PATRIC

23938134. VBITheMar51294_1604.

Phylogenomic databases

KO

K00050.

OMA

AHNDSHT.

ProtClustDB

CLSK875850.

Family and domain databases

Gene3D

3.40.1480.10. 1 hit.

InterPro

IPR025286. DUF4147.
IPR007835. MOFRL.
[Graphical view]

Pfam

PF13660. DUF4147. 1 hit.
PF05161. MOFRL. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q9X1S1.

Entry information

Entry name

Q9X1S1_THEMA

Accession

Primary (citable) accession number: Q9X1S1
Secondary accession number(s): G4FFX3

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	May 1, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)