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Q9X1H4 (RNPA_THEMA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 93. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease P protein component

Short name=RNase P protein
Short name=RNaseP protein
EC=3.1.26.5
Alternative name(s):
Protein C5
Gene names
Name:rnpA
Ordered Locus Names:TM_1463
OrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP]
Taxonomic identifier243274 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length117 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme By similarity. HAMAP-Rule MF_00227

Catalytic activity

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00227

Subunit structure

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit By similarity.

Sequence similarities

Belongs to the RnpA family.

Ontologies

Keywords
   Biological processtRNA processing
   LigandRNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processtRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionribonuclease P activity

Inferred from electronic annotation. Source: UniProtKB-EC

tRNA binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 117117Ribonuclease P protein component HAMAP-Rule MF_00227
PRO_0000198555

Secondary structure

...................... 117
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9X1H4 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 0E68A9B25D023C64

FASTA11714,317
        10         20         30         40         50         60 
MTESFTRRER LRLRRDFLLI FKEGKSLQNE YFVVLFRKNG LDYSRLGIVV KRKFGKATRR 

        70         80         90        100        110 
NKLKRWVREI FRRNKGVIPK GFDIVVIPRK KLSEEFERVD FWTVREKLLN LLKRIEG 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000512 Genomic DNA. Translation: AAD36531.1.
PIRH72251.
RefSeqNP_229262.1. NC_000853.1.
YP_007977818.1. NC_021214.1.
YP_008991448.1. NC_023151.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1NZ0X-ray1.20A/B/C/D2-117[»]
3Q1QX-ray3.80A3-117[»]
3Q1RX-ray4.21A3-117[»]
ProteinModelPortalQ9X1H4.
SMRQ9X1H4. Positions 11-117.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243274.TM1463.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD36531; AAD36531; TM_1463.
GeneID15495071.
18093247.
898016.
KEGGtma:TM1463.
tmm:Tmari_1469.
PATRIC23937878. VBITheMar51294_1477.

Phylogenomic databases

eggNOGCOG0594.
KOK03536.
OMAMTESFTR.
OrthoDBEOG6C01C6.
ProtClustDBCLSK875778.

Family and domain databases

Gene3D3.30.230.10. 1 hit.
HAMAPMF_00227. RNase_P.
InterProIPR020568. Ribosomal_S5_D2-typ_fold.
IPR014721. Ribosomal_S5_D2-typ_fold_subgr.
IPR000100. RNase_P.
IPR020539. RNase_P_CS.
[Graphical view]
PfamPF00825. Ribonuclease_P. 1 hit.
[Graphical view]
ProDomPD003629. Ribonuclease_P. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF54211. SSF54211. 1 hit.
TIGRFAMsTIGR00188. rnpA. 1 hit.
PROSITEPS00648. RIBONUCLEASE_P. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9X1H4.

Entry information

Entry nameRNPA_THEMA
AccessionPrimary (citable) accession number: Q9X1H4
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1999
Last modified: April 16, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references