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Q9X1B7

- CDSA_THEMA

UniProt

Q9X1B7 - CDSA_THEMA

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Protein
Phosphatidate cytidylyltransferase
Gene
cdsA, TM_1397
Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

CTP + phosphatidate = diphosphate + CDP-diacylglycerol.

Pathwayi

GO - Molecular functioni

  1. phosphatidate cytidylyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism

Enzyme and pathway databases

UniPathwayiUPA00557; UER00614.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidate cytidylyltransferase (EC:2.7.7.41)
Alternative name(s):
CDP-DAG synthase
CDP-DG synthase
CDP-diacylglycerol synthase
Short name:
CDS
CDP-diglyceride pyrophosphorylase
CDP-diglyceride synthase
CTP:phosphatidate cytidylyltransferase
Gene namesi
Name:cdsA
Ordered Locus Names:TM_1397
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei17 – 3721Helical; Reviewed prediction
Add
BLAST
Transmembranei55 – 7521Helical; Reviewed prediction
Add
BLAST
Transmembranei81 – 10121Helical; Reviewed prediction
Add
BLAST
Transmembranei104 – 12421Helical; Reviewed prediction
Add
BLAST
Transmembranei129 – 14921Helical; Reviewed prediction
Add
BLAST
Transmembranei170 – 19021Helical; Reviewed prediction
Add
BLAST
Transmembranei193 – 21321Helical; Reviewed prediction
Add
BLAST
Transmembranei248 – 26821Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 270270Phosphatidate cytidylyltransferase
PRO_0000090758Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243274.TM1397.

Family & Domainsi

Sequence similaritiesi

Belongs to the CDS family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0575.
KOiK00981.
OMAiLEMKERD.
OrthoDBiEOG6TBHJT.

Family and domain databases

InterProiIPR000374. PC_trans.
[Graphical view]
PfamiPF01148. CTP_transf_1. 1 hit.
[Graphical view]
PROSITEiPS01315. CDS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X1B7-1 [UniParc]FASTAAdd to Basket

« Hide

MDDLKTRVIT ASVVAPFVVL CFVSYESLIG LVSAILILAG YELITLEMKE    50
RDARFFYVIL LALYPVLYGL VFEEPTQPLS ILFITGVVFS LITDKDPSQV 100
FKTVAAFSIA LIYVTFFLSF FLPIYRDFGA ANALLVLTST WVFDSFAYFT 150
GLKFGRTRIS PRYSPRKSLE GVIGGFLGVV IYTFLYRLVV NDLLSVNVIS 200
FRTFLPFAAT VAIMDTFGDI FESALKRHYG VKDSGKTLPG HGGMLDRIDG 250
LLFVAPVSYI VFKILEGVVR 270
Length:270
Mass (Da):30,099
Last modified:November 1, 1999 - v1
Checksum:iBDAAF664120D7D3E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000512 Genomic DNA. Translation: AAD36468.1.
PIRiF72259.
RefSeqiNP_229198.1. NC_000853.1.
WP_004081613.1. NC_023151.1.
YP_007977753.1. NC_021214.1.
YP_008991512.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAAD36468; AAD36468; TM_1397.
GeneIDi898079.
KEGGitma:TM1397.
tmi:THEMA_07330.
tmm:Tmari_1404.
PATRICi23937740. VBITheMar51294_1409.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000512 Genomic DNA. Translation: AAD36468.1 .
PIRi F72259.
RefSeqi NP_229198.1. NC_000853.1.
WP_004081613.1. NC_023151.1.
YP_007977753.1. NC_021214.1.
YP_008991512.1. NC_023151.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243274.TM1397.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD36468 ; AAD36468 ; TM_1397 .
GeneIDi 898079.
KEGGi tma:TM1397.
tmi:THEMA_07330.
tmm:Tmari_1404.
PATRICi 23937740. VBITheMar51294_1409.

Phylogenomic databases

eggNOGi COG0575.
KOi K00981.
OMAi LEMKERD.
OrthoDBi EOG6TBHJT.

Enzyme and pathway databases

UniPathwayi UPA00557 ; UER00614 .

Family and domain databases

InterProi IPR000374. PC_trans.
[Graphical view ]
Pfami PF01148. CTP_transf_1. 1 hit.
[Graphical view ]
PROSITEi PS01315. CDS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Entry informationi

Entry nameiCDSA_THEMA
AccessioniPrimary (citable) accession number: Q9X1B7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: September 3, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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