Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Sensor histidine kinase

Gene

TM_1359

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei661ADPCombined sources1
Binding sitei689ADPCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi708 – 710ADPCombined sources3
Nucleotide bindingi714 – 718ADPCombined sources5

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseSAAS annotationImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.13.3. 6331.

Names & Taxonomyi

Protein namesi
Submitted name:
Sensor histidine kinaseImported
Gene namesi
Ordered Locus Names:TM_1359Imported
ORF Names:Tmari_1366Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000013901 Componenti: Chromosome
  • UP000008183 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

DIPiDIP-48290N.
STRINGi243274.TM1359.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3A0RX-ray3.80A408-755[»]
3A0SX-ray1.47A424-518[»]
3A0TX-ray1.91A605-755[»]
3A0VX-ray1.70A424-518[»]
3A0WX-ray1.69A/B605-755[»]
3A0XX-ray1.89A605-755[»]
3A0YX-ray1.57A/B605-755[»]
3A0ZX-ray1.75A/B605-755[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini412 – 457PAS (PER-ARNT-SIM)InterPro annotationAdd BLAST46
Domaini544 – 752Histidine kinaseInterPro annotationAdd BLAST209

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili152 – 190Sequence analysisAdd BLAST39

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105ES5. Bacteria.
COG0642. LUCA.
COG2202. LUCA.
COG2203. LUCA.
KOiK02486.
OMAiKANQRAM.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 2 hits.
3.30.565.10. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00989. PAS. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55781. SSF55781. 2 hits.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X180-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVPERLKQIK GIRILESEDE IPQEGFTCRF GKHTVVANDE ESFEIVRLYK
60 70 80 90 100
RLTVYELLLS LVDSICVHPK EEALRFSLKK VREFLDAEEV YLIEGDASYS
110 120 130 140 150
SKGEKLSIDE IKKKHPGASV REWRNKLHLV VVREGAFDEE EEVLCTKLLE
160 170 180 190 200
FIGNVSEKLW RLKEEVQKLK KSYEEQLKVS EIQKEHIKKM RIIYYVSQAM
210 220 230 240 250
RSVYDPNNLY RVILLSLVSE RGFNFDRAVL LKKDEGTGSL MVVSAVGGDT
260 270 280 290 300
LQEHEELKRY LRKRTLRYTD LVQFLREEAL TFSFETKFNE KIRGKRFYYR
310 320 330 340 350
EHPIFERVVL RKSIVRTSRE TLEKIRYEIE DVISILENDE FIVFPLVGRW
360 370 380 390 400
DTLGVVVVDN KFSKKEVTDL DLDVLKLFSE SAGLALENAY NYENLRKKTL
410 420 430 440 450
DLQRQNELVE HLRNFSESIL ESLETAIITL SKDGRITEWN KKAEQLFGLK
460 470 480 490 500
KENVLGRRLK DLPDFEEIGS VAESVFENKE PVFLNFYKFG ERYFNIRFSP
510 520 530 540 550
FRNAKTQLLE GVIITIDDVT ELYKYEEERK RRERLSILGE MTARVAHEIR
560 570 580 590 600
NPITIIGGFI MRMKKHLDDP ETLKKYINII TNELSRLETI VKEILEYSKE
610 620 630 640 650
RQVLEFTEFN LNELIREVYV LFEEKIRKMN IDFCFETDNE DLRVEADRTR
660 670 680 690 700
IKQVLINLVQ NAIEATGENG KIKITSEDMY TKVRVSVWNS GPPIPEELKE
710 720 730 740 750
KIFSPFFTTK TQGTGLGLSI CRKIIEDEHG GKIWTENREN GVVFIFEIPK

TPEKR
Length:755
Mass (Da):88,729
Last modified:November 1, 1999 - v1
Checksum:i61D11F4FDC4D0E9E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36429.1.
CP004077 Genomic DNA. Translation: AGL50290.1.
PIRiH72262.
RefSeqiNP_229160.1. NC_000853.1.
WP_004081555.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD36429; AAD36429; TM_1359.
AGL50290; AGL50290; Tmari_1366.
GeneIDi898121.
KEGGitma:TM1359.
tmi:THEMA_07545.
tmm:Tmari_1366.
tmw:THMA_1384.
PATRICi23937656. VBITheMar51294_1371.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36429.1.
CP004077 Genomic DNA. Translation: AGL50290.1.
PIRiH72262.
RefSeqiNP_229160.1. NC_000853.1.
WP_004081555.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3A0RX-ray3.80A408-755[»]
3A0SX-ray1.47A424-518[»]
3A0TX-ray1.91A605-755[»]
3A0VX-ray1.70A424-518[»]
3A0WX-ray1.69A/B605-755[»]
3A0XX-ray1.89A605-755[»]
3A0YX-ray1.57A/B605-755[»]
3A0ZX-ray1.75A/B605-755[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-48290N.
STRINGi243274.TM1359.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD36429; AAD36429; TM_1359.
AGL50290; AGL50290; Tmari_1366.
GeneIDi898121.
KEGGitma:TM1359.
tmi:THEMA_07545.
tmm:Tmari_1366.
tmw:THMA_1384.
PATRICi23937656. VBITheMar51294_1371.

Phylogenomic databases

eggNOGiENOG4105ES5. Bacteria.
COG0642. LUCA.
COG2202. LUCA.
COG2203. LUCA.
KOiK02486.
OMAiKANQRAM.

Enzyme and pathway databases

BRENDAi2.7.13.3. 6331.

Family and domain databases

Gene3Di1.10.287.130. 1 hit.
3.30.450.40. 2 hits.
3.30.565.10. 1 hit.
InterProiIPR003018. GAF.
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR000014. PAS.
IPR013767. PAS_fold.
IPR004358. Sig_transdc_His_kin-like_C.
[Graphical view]
PfamiPF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00989. PAS. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00091. PAS. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55781. SSF55781. 2 hits.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
TIGRFAMsiTIGR00229. sensory_box. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50112. PAS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9X180_THEMA
AccessioniPrimary (citable) accession number: Q9X180
Secondary accession number(s): G4FF95
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: November 2, 2016
This is version 131 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.