Arabinogalactan endo-1,4-beta-galactosidase, putative

Preferred order of sections

Names and origin

Protein names

Submitted name:
Arabinogalactan endo-1,4-beta-galactosidase, putative EMBL AAD36276.1

Gene names

Ordered Locus Names:

TM_1201

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	606 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Calcium PDB 2XOM PDB 2XON Metal-binding PDB 2XOM PDB 2XON
Technical term	3D-structure PDB 2XOM PDB 2XON Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	glucosidase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Region

506 – 508

3

Galactose binding PDB 2XOM PDB 2XON

Sites

Metal binding

469

1

Calcium; via carbonyl oxygen PDB 2XOM PDB 2XON

Metal binding

471

1

Calcium PDB 2XOM PDB 2XON

Metal binding

500

1

Calcium PDB 2XOM PDB 2XON

Metal binding

503

1

Calcium; via carbonyl oxygen PDB 2XOM PDB 2XON

Metal binding

598

1

Calcium PDB 2XOM PDB 2XON

Binding site

497

1

Galactose PDB 2XOM PDB 2XON

Binding site

563

1

Galactose PDB 2XON

Binding site

594

1

Galactose PDB 2XOM PDB 2XON

Sequences

Sequence

Length

Mass (Da)

Tools

Q9X0S8 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 0A4C121D93ABCB00
Show »

FASTA

606

68,620

        10         20         30         40         50         60 
MRGVLFVLMI SSMAFGLIVN PVENLREDFI FGMDVSMLYE IEQLGGKYFE NGVEKDCLEI 

        70         80         90        100        110        120 
LKNHGINWIR LRVWNDPRDE NGNPLGGGNC DYLKMTEIAK RAKNLGMKVL LDFHYSDWWA 

       130        140        150        160        170        180 
DPGKQNKPKE WEYLHGELLE RAVYSYTKLV LNHMRRNGAL PDMVQVGNEV NNGFLWPDGK 

       190        200        210        220        230        240 
ISGEGAGGFD GFTRLLKAAI KAVREVDPDI KIVIHLAEGG NNSLFRWFFD EITRRNVDFD 

       250        260        270        280        290        300 
VIGVSYYPYW HGTLEDLKNN LYDIATRYNK DVLVVETAYA WTLEDGDGYP NIFNGEEMEL 

       310        320        330        340        350        360 
TGGYKATVQG QATFLRDLIE VVNSVPNGHG LGIFYWEGDW IPVRGAGWKT GEGNPWDNQA 

       370        380        390        400        410        420 
MFDFSGNALP SLNVFKLVKT SSPVEIAIKE ILPVEVTTNL GEVPKFPDAV KVLFSDDSIR 

       430        440        450        460        470        480 
SLPVEWNFDS ALVEESGVYK VEGYIKDIDR KIFATLTVKG SRNYLKNPGF ETGEFSPWRV 

       490        500        510        520        530        540 
SGDKKAVKVV KANPSSNAHQ GEYAVNFWLD ESFSFELSQE VELPAGVYRV GFWTHGEKGV 

       550        560        570        580        590        600 
KIALKVSDYG GNERSVEVET TGWLEWKNPE IRNIKVETGR IKITVSVEGR AGDWGFIDDF 


YLFREE

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Recognition of the helical structure of beta-1,4-galactan by a new family of carbohydrate-binding modules." Cid M., Pedersen H.L., Kaneko S., Coutinho P.M., Henrissat B., Willats W.G., Boraston A.B. J. Biol. Chem. 285:35999-36009(2010) [PubMed: 20826814] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (0.95 ANGSTROMS) OF 461-606 IN COMPLEX WITH CALCIUM AND GALACTOSE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD36276.1.

PIR

G72282.

RefSeq

NP_229006.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2XOM	X-ray	0.95	A	461-606	[»]
2XON	X-ray	1.40	A/L	461-606	[»]

ProteinModelPortal

Q9X0S8.

ModBase

Search...

Protein family/group databases

CAZy

GH53. Glycoside Hydrolase Family 53.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

898283.

GenomeReviews

Gene locus TM_1201 in contig AE000512_GR.

KEGG

tma:TM1201.

NMPDR

fig|243274.1.peg.1190.

PATRIC

23937344. VBITheMar51294_1219.

TIGR

TM_1201.

Phylogenomic databases

HOGENOM

HBG465679.

OMA

MVAETSW.

PhylomeDB

Q9X0S8.

ProtClustDB

CLSK875631.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_1201-MONOMER.

Family and domain databases

InterPro

IPR011081. Big_4.
IPR011683. Glyco_hydro_53.
IPR013781. Glyco_hydro_subgr_catalytic.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

Gene3D

G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.

KO

K01224.

Pfam

PF07532. Big_4. 1 hit.
PF07745. Glyco_hydro_53. 1 hit.
[Graphical view]

SUPFAM

SSF51445. Glyco_hydro_cat. 1 hit.

ProtoNet

Search...

Entry information

Entry name

Q9X0S8_THEMA

Accession

Primary (citable) accession number: Q9X0S8

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)