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Protein

Arabinogalactan endo-beta-1,4-galactanase

Gene

TM_1201

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

The enzyme specifically hydrolyzes (1->4)-beta-D-galactosidic linkages in type I arabinogalactans.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi469Calcium; via carbonyl oxygenCombined sources1
Metal bindingi471CalciumCombined sources1
Binding sitei497GalactoseCombined sources1
Metal bindingi500CalciumCombined sources1
Metal bindingi503Calcium; via carbonyl oxygenCombined sources1
Binding sitei516GalactoseCombined sources1
Binding sitei563GalactoseCombined sources1
Metal bindingi598CalciumCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidaseUniRule annotation, Hydrolase
LigandCalciumCombined sources, Metal-bindingCombined sources

Enzyme and pathway databases

BRENDAi3.2.1.89. 6331.

Protein family/group databases

CAZyiCBM61. Carbohydrate-Binding Module Family 61.
GH53. Glycoside Hydrolase Family 53.

Names & Taxonomyi

Protein namesi
Recommended name:
Arabinogalactan endo-beta-1,4-galactanaseUniRule annotation (EC:3.2.1.89UniRule annotation)
Gene namesi
Ordered Locus Names:TM_1201Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243274.TM1201.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2XOMX-ray0.95A461-606[»]
2XONX-ray1.40A/L461-606[»]
SMRiQ9X0S8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 375Glyco_hydro_53InterPro annotationAdd BLAST346
Domaini392 – 446Big_4InterPro annotationAdd BLAST55

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni506 – 508Galactose bindingCombined sources3
Regioni591 – 594Galactose bindingCombined sources4

Sequence similaritiesi

Belongs to the glycosyl hydrolase 53 family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106FKC. Bacteria.
COG3867. LUCA.
KOiK01224.
OMAiGIFYWEG.

Family and domain databases

Gene3Di2.60.120.260. 1 hit.
InterProiView protein in InterPro
IPR011081. Big_4.
IPR008979. Galactose-bd-like.
IPR011683. Glyco_hydro_53.
IPR017853. Glycoside_hydrolase_SF.
PfamiView protein in Pfam
PF07532. Big_4. 1 hit.
PF07745. Glyco_hydro_53. 1 hit.
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9X0S8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRGVLFVLMI SSMAFGLIVN PVENLREDFI FGMDVSMLYE IEQLGGKYFE
60 70 80 90 100
NGVEKDCLEI LKNHGINWIR LRVWNDPRDE NGNPLGGGNC DYLKMTEIAK
110 120 130 140 150
RAKNLGMKVL LDFHYSDWWA DPGKQNKPKE WEYLHGELLE RAVYSYTKLV
160 170 180 190 200
LNHMRRNGAL PDMVQVGNEV NNGFLWPDGK ISGEGAGGFD GFTRLLKAAI
210 220 230 240 250
KAVREVDPDI KIVIHLAEGG NNSLFRWFFD EITRRNVDFD VIGVSYYPYW
260 270 280 290 300
HGTLEDLKNN LYDIATRYNK DVLVVETAYA WTLEDGDGYP NIFNGEEMEL
310 320 330 340 350
TGGYKATVQG QATFLRDLIE VVNSVPNGHG LGIFYWEGDW IPVRGAGWKT
360 370 380 390 400
GEGNPWDNQA MFDFSGNALP SLNVFKLVKT SSPVEIAIKE ILPVEVTTNL
410 420 430 440 450
GEVPKFPDAV KVLFSDDSIR SLPVEWNFDS ALVEESGVYK VEGYIKDIDR
460 470 480 490 500
KIFATLTVKG SRNYLKNPGF ETGEFSPWRV SGDKKAVKVV KANPSSNAHQ
510 520 530 540 550
GEYAVNFWLD ESFSFELSQE VELPAGVYRV GFWTHGEKGV KIALKVSDYG
560 570 580 590 600
GNERSVEVET TGWLEWKNPE IRNIKVETGR IKITVSVEGR AGDWGFIDDF

YLFREE
Length:606
Mass (Da):68,620
Last modified:November 1, 1999 - v1
Checksum:i0A4C121D93ABCB00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36276.1.
PIRiG72282.
RefSeqiNP_229006.1. NC_000853.1.
WP_004080113.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD36276; AAD36276; TM_1201.
AGL50132; AGL50132; Tmari_1208.
GeneIDi898283.
KEGGitma:TM1201.
tmi:THEMA_08325.
tmm:Tmari_1208.
tmw:THMA_1227.
PATRICifig|243274.17.peg.1206.

Similar proteinsi

Entry informationi

Entry nameiQ9X0S8_THEMA
AccessioniPrimary (citable) accession number: Q9X0S8
Secondary accession number(s): G4FEE5
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported