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Q9X0N8

- 6PGL_THEMA

UniProt

Q9X0N8 - 6PGL_THEMA

Protein

6-phosphogluconolactonase

Gene

pgl

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 94 (01 Oct 2014)
      Sequence version 1 (01 Nov 1999)
      Previous versions | rss
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    Functioni

    Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

    Catalytic activityi

    6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

    Pathwayi

    GO - Molecular functioni

    1. 6-phosphogluconolactonase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciTMAR243274:GC6P-1183-MONOMER.
    UniPathwayiUPA00115; UER00409.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    6-phosphogluconolactonase (EC:3.1.1.31)
    Short name:
    6PGL
    Gene namesi
    Name:pgl
    Synonyms:devB
    Ordered Locus Names:TM_1154
    OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    Taxonomic identifieri243274 [NCBI]
    Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
    ProteomesiUP000008183: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2202206-phosphogluconolactonasePRO_0000090108Add
    BLAST

    Proteomic databases

    PRIDEiQ9X0N8.

    Interactioni

    Protein-protein interaction databases

    STRINGi243274.TM1154.

    Structurei

    Secondary structure

    1
    220
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi4 – 118
    Helixi13 – 3119
    Beta strandi35 – 395
    Helixi45 – 528
    Helixi59 – 613
    Beta strandi62 – 7211
    Helixi80 – 878
    Turni88 – 914
    Helixi96 – 983
    Helixi108 – 12215
    Beta strandi127 – 1315
    Helixi145 – 1484
    Beta strandi151 – 1566
    Beta strandi158 – 1603
    Turni161 – 1644
    Beta strandi167 – 1704
    Helixi172 – 1754
    Beta strandi179 – 1879
    Helixi188 – 19811
    Helixi204 – 2074
    Beta strandi211 – 2199

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1PBTX-ray1.70A1-220[»]
    1VL1X-ray1.55A1-220[»]
    ProteinModelPortaliQ9X0N8.
    SMRiQ9X0N8. Positions 1-220.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ9X0N8.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0363.
    KOiK01057.
    OMAiAGDPERN.
    OrthoDBiEOG63FW46.

    Family and domain databases

    InterProiIPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view]
    PfamiPF01182. Glucosamine_iso. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01198. pgl. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q9X0N8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEKTVIYLLE DGYVDFVVEK IRTKMEKLLE EKDKIFVVLA GGRTPLPVYE    50
    KLAEQKFPWN RIHFFLSDER YVPLDSDQSN FRNINEVLFS RAKIPSGNVH 100
    YVDTSLPIEK ACEKYEREIR SATDQFDLAI LGMGPDGHVA SIFDLETGNK 150
    DNLVTFTDPS GDPKVPRVTL TFRALNTSLY VLFLIRGKEK INRLTEILKD 200
    TPLPAYFVRG KEKTVWFVGK 220
    Length:220
    Mass (Da):25,325
    Last modified:November 1, 1999 - v1
    Checksum:i9B0FD07EE01E60C3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000512 Genomic DNA. Translation: AAD36230.1.
    PIRiF72289.
    RefSeqiNP_228960.1. NC_000853.1.
    YP_007977510.1. NC_021214.1.
    YP_008991748.1. NC_023151.1.

    Genome annotation databases

    EnsemblBacteriaiAAD36230; AAD36230; TM_1154.
    GeneIDi898332.
    KEGGitma:TM1154.
    tmi:THEMA_08570.
    tmm:Tmari_1161.
    PATRICi23937245. VBITheMar51294_1171.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000512 Genomic DNA. Translation: AAD36230.1 .
    PIRi F72289.
    RefSeqi NP_228960.1. NC_000853.1.
    YP_007977510.1. NC_021214.1.
    YP_008991748.1. NC_023151.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1PBT X-ray 1.70 A 1-220 [» ]
    1VL1 X-ray 1.55 A 1-220 [» ]
    ProteinModelPortali Q9X0N8.
    SMRi Q9X0N8. Positions 1-220.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 243274.TM1154.

    Proteomic databases

    PRIDEi Q9X0N8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD36230 ; AAD36230 ; TM_1154 .
    GeneIDi 898332.
    KEGGi tma:TM1154.
    tmi:THEMA_08570.
    tmm:Tmari_1161.
    PATRICi 23937245. VBITheMar51294_1171.

    Phylogenomic databases

    eggNOGi COG0363.
    KOi K01057.
    OMAi AGDPERN.
    OrthoDBi EOG63FW46.

    Enzyme and pathway databases

    UniPathwayi UPA00115 ; UER00409 .
    BioCyci TMAR243274:GC6P-1183-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q9X0N8.

    Family and domain databases

    InterProi IPR005900. 6-phosphogluconolactonase_DevB.
    IPR006148. Glc/Gal-6P_isomerase.
    [Graphical view ]
    Pfami PF01182. Glucosamine_iso. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01198. pgl. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

    Entry informationi

    Entry namei6PGL_THEMA
    AccessioniPrimary (citable) accession number: Q9X0N8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 30, 2000
    Last sequence update: November 1, 1999
    Last modified: October 1, 2014
    This is version 94 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3