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Q9X0N8 (6PGL_THEMA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6-phosphogluconolactonase
Short name=6PGL
EC=3.1.1.31
Gene names
Name:pgl
Synonyms:devB
Ordered Locus Names:TM_1154
OrganismThermotoga maritima
Taxonomic identifier2336 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

Catalytic activity

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 2/3.

Sequence similarities

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

Ontologies

Keywords
   Molecular functionHydrolase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: InterPro

   Molecular function6-phosphogluconolactonase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 2202206-phosphogluconolactonase
PRO_0000090108

Secondary structure

1 ....................................... 220
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q9X0N8 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 9B0FD07EE01E60C3

FASTA22025,325
        10         20         30         40         50         60 
MEKTVIYLLE DGYVDFVVEK IRTKMEKLLE EKDKIFVVLA GGRTPLPVYE KLAEQKFPWN 

        70         80         90        100        110        120 
RIHFFLSDER YVPLDSDQSN FRNINEVLFS RAKIPSGNVH YVDTSLPIEK ACEKYEREIR 

       130        140        150        160        170        180 
SATDQFDLAI LGMGPDGHVA SIFDLETGNK DNLVTFTDPS GDPKVPRVTL TFRALNTSLY 

       190        200        210        220 
VLFLIRGKEK INRLTEILKD TPLPAYFVRG KEKTVWFVGK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000512 Genomic DNA. Translation: AAD36230.1.
PIRF72289.
RefSeqNP_228960.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1PBTX-ray1.70A1-220[»]
1VL1X-ray1.55A1-220[»]
ProteinModelPortalQ9X0N8.
SMRQ9X0N8. Positions 1-220.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID898332.
GenomeReviewsGene locus TM_1154 in contig AE000512_GR.
KEGGtma:TM1154.
NMPDRfig|243274.1.peg.1144.
PATRIC23937245. VBITheMar51294_1171.
TIGRTM_1154.

Phylogenomic databases

HOGENOMHBG725991.
OMALFPGQTN.
PhylomeDBQ9X0N8.
ProtClustDBCLSK795722.

Enzyme and pathway databases

BioCycTMAR243274:TM_1154-MONOMER.

Family and domain databases

InterProIPR005900. 6-phosphogluconolactonase_DevB.
IPR006148. Glc/Gal-6P_isomerase.
[Graphical view]
KOK01057.
PfamPF01182. Glucosamine_iso. 1 hit.
[Graphical view]
TIGRFAMsTIGR01198. Pgl. 1 hit.
ProtoNetSearch...

Entry information

Entry name6PGL_THEMA
AccessionPrimary (citable) accession number: Q9X0N8
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1999
Last modified: January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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