Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Methyl-accepting chemotaxis protein 2

Gene

mcp2

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of methylation.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransducer
Biological processChemotaxis

Names & Taxonomyi

Protein namesi
Recommended name:
Methyl-accepting chemotaxis protein 2
Gene namesi
Name:mcp2
Ordered Locus Names:TM_1143
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei9 – 29HelicalSequence analysisAdd BLAST21
Transmembranei151 – 171HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002509941 – 530Methyl-accepting chemotaxis protein 2Add BLAST530

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei274Glutamate methyl ester (Gln)1 Publication1
Modified residuei281Glutamate methyl ester (Glu)1 Publication1
Modified residuei498Deamidated glutamine1 Publication1
Modified residuei505Glutamate methyl ester (Glu)1 Publication1

Keywords - PTMi

Methylation

Interactioni

Protein-protein interaction databases

DIPiDIP-29072N
STRINGi243274.TM1143

Structurei

Secondary structure

1530
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni222 – 224Combined sources3
Helixi225 – 341Combined sources117
Helixi344 – 372Combined sources29
Helixi378 – 414Combined sources37
Helixi417 – 432Combined sources16
Helixi435 – 518Combined sources84
Turni520 – 522Combined sources3
Helixi523 – 528Combined sources6

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2CH7X-ray2.50A/B225-529[»]
3JA6electron microscopy12.70G/I/K/M/O/Q225-529[»]
H/J/L/N/P/R225-528[»]
ProteinModelPortaliQ9X0M7
SMRiQ9X0M7
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ9X0M7

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini152 – 222HAMPAdd BLAST71
Domaini244 – 480Methyl-accepting transducerPROSITE-ProRule annotationAdd BLAST237

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105C8Q Bacteria
COG0840 LUCA
InParanoidiQ9X0M7
KOiK03406
OMAiHTIALLP

Family and domain databases

InterProiView protein in InterPro
IPR004090 Chemotax_Me-accpt_rcpt
IPR004089 MCPsignal_dom
IPR000727 T_SNARE_dom
PfamiView protein in Pfam
PF00015 MCPsignal, 1 hit
PRINTSiPR00260 CHEMTRNSDUCR
SMARTiView protein in SMART
SM00283 MA, 1 hit
PROSITEiView protein in PROSITE
PS50111 CHEMOTAXIS_TRANSDUC_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9X0M7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLKGKTLLV STITLAAVVL VALLGGSVFL KAGQNVRKAF EEYELAVEAL
60 70 80 90 100
DKLGELETKV ALFVNNAAKI EEVSSLFNEL KKVADKIPSL KEHMDALERN
110 120 130 140 150
ISEIISGKTE VVSRIQSSVD QVKEDIMANL DRTRENLDKE ISYSSELIRN
160 170 180 190 200
VLFIVLPIVA VASGVFLFVM ISRSLRLLKP VMEASRSLRN NDLTINIQEA
210 220 230 240 250
KGKDEISTLL NEFKASIEYL RNNLKDVQTE TFSVAESIEE ISKANEEITN
260 270 280 290 300
QLLGISKEMD NISTRIESIS ASVQETTAGS EEISSATKNI ADSAQQAASF
310 320 330 340 350
ADQSTQLAKE AGDALKKVIE VTRMISNSAK DVERVVESFQ KGAEEITSFV
360 370 380 390 400
ETINAIAEQT NLLALNAAIE AARAGEAGRG FAVVADEIRK LAEESQQASE
410 420 430 440 450
NVRRVVNEIR SIAEDAGKVS SEITARVEEG TKLADEADEK LNSIVGAVER
460 470 480 490 500
INEMLQNIAA AIEEQTAAVD EITTAMTENA KNAEEITNSV KEVNARLQEI
510 520 530
SASTEEVTSR VQTIRENVQM LKEIVARYKI
Length:530
Mass (Da):57,929
Last modified:November 1, 1999 - v1
Checksum:iC04149A4F46890CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA Translation: AAD36219.1
PIRiC72291
RefSeqiNP_228949.1, NC_000853.1
WP_004080253.1, NZ_CP011107.1

Genome annotation databases

EnsemblBacteriaiAAD36219; AAD36219; TM_1143
GeneIDi898621
KEGGitma:TM1143

Similar proteinsi

Entry informationi

Entry nameiMCP2_THEMA
AccessioniPrimary (citable) accession number: Q9X0M7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 1, 1999
Last modified: March 28, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health