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Q9X0C0 (Q9X0C0_THEMA) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names

Transcriptional regulator, TetR family EMBL AAD36107.1
Gene names
Ordered Locus Names:TM_1030 EMBL AAD36107.1
ORF Names:THEMA_09210 EMBL AHD19062.1
OrganismThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP] EMBL AAD36107.1
Taxonomic identifier243274 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length200 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains 1 HTH tetR-type DNA-binding domain. RuleBase RU000710

Contains HTH tetR-type DNA-binding domain. SAAS SAAS001647

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region158 – 1614Hexaethylene glycol binding PDB 2IEK

Sites

Binding site851Hexaethylene glycol PDB 2IEK
Binding site891Hexaethylene glycol PDB 2IEK

Sequences

Sequence LengthMass (Da)Tools
Q9X0C0 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: CBF79565CB2D4273

FASTA20023,801
        10         20         30         40         50         60 
MLSKRDAILK AAVEVFGKKG YDRATTDEIA EKAGVAKGLI FHYFKNKEEL YYQAYMSVTE 

        70         80         90        100        110        120 
KLQKEFENFL MKNRNRDIFD FMERWIEKKL EYSASHPEEA DFLITLVSVD EGLRKRILLD 

       130        140        150        160        170        180 
LEKSQRVFFD FVREKLKDLD LAEDVTEEIA LKFLMWFFSG FEEVYLRTYQ GKPELLKRDM 

       190        200 
NTLVEEVKVM LRILKKGMTK 

« Hide

References

« Hide 'large scale' references
[1]"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. expand/collapse author list , Phillips C.A., Richardson D., Heidelberg J., Sutton G.G., Fleischmann R.D., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099 and MSB8 EMBL AAD36107.1.
[2]"Crystal structure of transcriptional regulator (tm1030) at 1.75A resolution."
Koclega K.D., Chruszcz M., Minor W.
Submitted (SEP-2006) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).
[3]"New crystal form of transcriptional regulator tm1030 from Thermotoga maritima."
Koclega K.D., Chruszcz M., Minor W.
Submitted (SEP-2006) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (1.83 ANGSTROMS) IN COMPLEX WITH HEXAETHYLENE GLYCOL.
[4]"Crystal structure of a transcriptional regulator TM1030 from Thermotoga maritima solved by an unusual MAD experiment."
Koclega K.D., Chruszcz M., Zimmerman M.D., Cymborowski M., Evdokimova E., Minor W.
J. Struct. Biol. 159:424-432(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
[5]"Crystal structure of TM1030 from Thermotoga maritima at 2.3 A resolution reveals molecular details of its transcription repressor function."
Premkumar L., Rife C.L., Sri Krishna S., McMullan D., Miller M.D., Abdubek P., Ambing E., Astakhova T., Axelrod H.L., Canaves J.M., Carlton D., Chiu H.J., Clayton T., DiDonato M., Duan L., Elsliger M.A., Feuerhelm J., Floyd R. expand/collapse author list , Grzechnik S.K., Hale J., Hampton E., Han G.W., Haugen J., Jaroszewski L., Jin K.K., Klock H.E., Knuth M.W., Koesema E., Kovarik J.S., Kreusch A., Levin I., McPhillips T.M., Morse A.T., Nigoghossian E., Okach L., Oommachen S., Paulsen J., Quijano K., Reyes R., Rezezadeh F., Rodionov D., Schwarzenbacher R., Spraggon G., van den Bedem H., White A., Wolf G., Xu Q., Hodgson K.O., Wooley J., Deacon A.M., Godzik A., Lesley S.A., Wilson I.A.
Proteins 68:418-424(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).
[6]"'Hot' macromolecular crystals."
Koclega K.D., Chruszcz M., Zimmerman M.D., Bujacz G., Minor W.
Cryst. Growth Des. 10:580-580(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS).
[7]"Crystal structure of the transcriptional regulator TM1030 with 24bp DNA oligonucleotide."
Koclega K.D., Chruszcz M., Cooper D.R., Petkowski J.J., Tkaczuk K.L., Joachimiak A., Minor W.
Submitted (NOV-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (3.20 ANGSTROMS).
[8]"Crystal structure of transcriptional regulator TM1030 with octanol."
Koclega K.D., Chruszcz M., Cooper D.R., Petkowski J.J., Tkaczuk K.L., Joachimiak A., Minor W.
Submitted (NOV-2012) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
[9]DOE Joint Genome Institute
Noll K.M., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K., Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A., Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.
Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: MSB8 EMBL AHD19062.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000512 Genomic DNA. Translation: AAD36107.1.
CP007013 Genomic DNA. Translation: AHD19062.1.
PIRE72303.
RefSeqNP_228836.1. NC_000853.1.
YP_008991874.1. NC_023151.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1Z77X-ray2.00A1-200[»]
1ZKGX-ray2.30A/B1-200[»]
2ID6X-ray1.75A1-200[»]
2IEKX-ray1.83A1-200[»]
3IH2X-ray2.30A1-200[»]
3IH3X-ray2.35A1-200[»]
3IH4X-ray2.30A1-200[»]
4I6ZX-ray3.20A/B1-200[»]
4I76X-ray2.10A/B1-200[»]
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243274.TM1030.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD36107; AAD36107; TM_1030.
GeneID897092.
KEGGtma:TM1030.
tmi:THEMA_09210.
PATRIC23936989. VBITheMar51294_1043.

Phylogenomic databases

OMAMERWIEK.
OrthoDBEOG6ZH2G9.

Enzyme and pathway databases

BioCycTMAR243274:GC6P-1059-MONOMER.

Family and domain databases

Gene3D1.10.10.60. 2 hits.
1.10.357.10. 1 hit.
InterProIPR023772. DNA-bd_HTH_TetR-type_CS.
IPR009057. Homeodomain-like.
IPR001647. HTH_TetR.
IPR015893. Tet_transcr_reg_TetR-like_C.
IPR011075. Tet_transcr_reg_TetR-rel_C.
[Graphical view]
PfamPF00440. TetR_N. 1 hit.
[Graphical view]
PRINTSPR00455. HTHTETR.
SUPFAMSSF46689. SSF46689. 1 hit.
SSF48498. SSF48498. 1 hit.
PROSITEPS01081. HTH_TETR_1. 1 hit.
PS50977. HTH_TETR_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ9X0C0.

Entry information

Entry nameQ9X0C0_THEMA
AccessionPrimary (citable) accession number: Q9X0C0
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: July 9, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)