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Protein
Submitted name:

Oxidoreductase, aldo/keto reductase family

Gene

TM_1009

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei45 – 451NADPCombined sources
Binding sitei162 – 1621NADPCombined sources
Binding sitei199 – 1991NADPCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi21 – 222NADPCombined sources
Nucleotide bindingi140 – 1412NADPCombined sources
Nucleotide bindingi188 – 1936NADPCombined sources
Nucleotide bindingi233 – 2353NADPCombined sources
Nucleotide bindingi239 – 2435NADPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

NADPCombined sources, Nucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-1038-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Oxidoreductase, aldo/keto reductase familyImported
Gene namesi
Ordered Locus Names:TM_1009Imported
ORF Names:Tmari_1012Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000013901 Componenti: Chromosome
  • UP000008183 Componenti: Chromosome

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VP5X-ray2.40A/B1-286[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini23 – 262240Aldo_ket_redInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105CV8. Bacteria.
COG0656. LUCA.
OMAiTTKIWIS.
OrthoDBiEOG68H8C2.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X0A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVPKVTLNN GVEMPILGYG VFQIPPEKTE ECVYEAIKVG YRLIDTAASY
60 70 80 90 100
MNEEGVGRAI KRAIDEGIVR REELFVTTKL WVSDVGYEST KKAFEKSLKK
110 120 130 140 150
LQLEYIDLYL IHQPFGDVHC AWKAMEEMYK DGLVRAIGVS NFYPDRLMDL
160 170 180 190 200
MVHHEIVPAV NQIEIHPFYQ RQEEIEFMRN YNIQPEAWGP FAEGRKNIFQ
210 220 230 240 250
NGVLRSIAEK YGKTVAQVIL RWLTQKGIVA IPKTVRRERM KENISIFDFE
260 270 280
LTQEDMEKIA TLDEGQSAFF SHRDPEVVKW ICSLKR
Length:286
Mass (Da):33,244
Last modified:November 1, 1999 - v1
Checksum:iE8A95EF2AC44FCEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36074.1.
CP004077 Genomic DNA. Translation: AGL49936.1.
PIRiA72308.
RefSeqiNP_228815.1. NC_000853.1.
WP_004080532.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD36074; AAD36074; TM_1009.
AGL49936; AGL49936; Tmari_1012.
GeneIDi896824.
KEGGitma:TM1009.
tmi:THEMA_09310.
tmm:Tmari_1012.
tmw:THMA_1031.
PATRICi23936947. VBITheMar51294_1022.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36074.1.
CP004077 Genomic DNA. Translation: AGL49936.1.
PIRiA72308.
RefSeqiNP_228815.1. NC_000853.1.
WP_004080532.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1VP5X-ray2.40A/B1-286[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD36074; AAD36074; TM_1009.
AGL49936; AGL49936; Tmari_1012.
GeneIDi896824.
KEGGitma:TM1009.
tmi:THEMA_09310.
tmm:Tmari_1012.
tmw:THMA_1031.
PATRICi23936947. VBITheMar51294_1022.

Phylogenomic databases

eggNOGiENOG4105CV8. Bacteria.
COG0656. LUCA.
OMAiTTKIWIS.
OrthoDBiEOG68H8C2.

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-1038-MONOMER.

Family and domain databases

Gene3Di3.20.20.100. 1 hit.
InterProiIPR001395. Aldo/ket_red/Kv-b.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
PANTHERiPTHR11732. PTHR11732. 1 hit.
PfamiPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PRINTSiPR00069. ALDKETRDTASE.
SUPFAMiSSF51430. SSF51430. 1 hit.
PROSITEiPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported and MSB8Imported.
  2. "The genome organization of Thermotoga maritima reflects its lifestyle."
    Latif H., Lerman J.A., Portnoy V.A., Tarasova Y., Nagarajan H., Schrimpe-Rutledge A.C., Smith R.D., Adkins J.N., Lee D.H., Qiu Y., Zengler K.
    PLoS Genet. 9:E1003485-E1003485(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported and MSB8Imported.

Entry informationi

Entry nameiQ9X0A2_THEMA
AccessioniPrimary (citable) accession number: Q9X0A2
Secondary accession number(s): G4FEY8
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: March 16, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.