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Q9X0A2 (Q9X0A2_THEMA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Oxidoreductase, aldo/keto reductase family EMBL AAD36074.1
Gene names
Ordered Locus Names:TM_1009
OrganismThermotoga maritima
Taxonomic identifier2336 [NCBI]
Taxonomic lineageBacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding21 – 222NADP PDB 1VP5
Nucleotide binding140 – 1412NADP PDB 1VP5
Nucleotide binding188 – 1936NADP PDB 1VP5
Nucleotide binding233 – 2353NADP PDB 1VP5
Nucleotide binding239 – 2435NADP PDB 1VP5

Sites

Active site501Proton donor By similarity PIRSR PIRSR000097-1
Binding site451NADP PDB 1VP5
Binding site1621NADP PDB 1VP5
Binding site1991NADP PDB 1VP5

Sequences

Sequence LengthMass (Da)Tools
Q9X0A2 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: E8A95EF2AC44FCEB

FASTA28633,244
        10         20         30         40         50         60 
MQVPKVTLNN GVEMPILGYG VFQIPPEKTE ECVYEAIKVG YRLIDTAASY MNEEGVGRAI 

        70         80         90        100        110        120 
KRAIDEGIVR REELFVTTKL WVSDVGYEST KKAFEKSLKK LQLEYIDLYL IHQPFGDVHC 

       130        140        150        160        170        180 
AWKAMEEMYK DGLVRAIGVS NFYPDRLMDL MVHHEIVPAV NQIEIHPFYQ RQEEIEFMRN 

       190        200        210        220        230        240 
YNIQPEAWGP FAEGRKNIFQ NGVLRSIAEK YGKTVAQVIL RWLTQKGIVA IPKTVRRERM 

       250        260        270        280 
KENISIFDFE LTQEDMEKIA TLDEGQSAFF SHRDPEVVKW ICSLKR

« Hide

References

« Hide 'large scale' references
[1]"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. expand/collapse author list , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
Nature 399:323-329(1999) [PubMed: 10360571] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]"Crystal structure of 2,5-diketo-D-gluconic acid reductase (TM1009) from Thermotoga maritima at 2.40 A resolution."
Joint Center for Structural Genomics (JCSG)
Submitted (OCT-2004) to the PDB data bank
Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) IN COMPLEX WITH NADP.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000512 Genomic DNA. Translation: AAD36074.1.
PIRA72308.
RefSeqNP_228815.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1VP5X-ray2.40A/B1-286[»]
ProteinModelPortalQ9X0A2.
SMRQ9X0A2. Positions 2-285.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID896824.
GenomeReviewsGene locus TM_1009 in contig AE000512_GR.
KEGGtma:TM1009.
NMPDRfig|243274.1.peg.999.
PATRIC23936947. VBITheMar51294_1022.
TIGRTM_1009.

Phylogenomic databases

HOGENOMHBG605727.
OMAKTVRRER.
PhylomeDBQ9X0A2.
ProtClustDBCLSK875520.

Enzyme and pathway databases

BioCycTMAR243274:TM_1009-MONOMER.

Family and domain databases

InterProIPR001395. Aldo/ket_red.
IPR018170. Aldo/ket_reductase_CS.
IPR020471. Aldo/keto_reductase_subgr.
IPR023210. NADP_OxRdtase_dom.
[Graphical view]
Gene3DG3DSA:3.20.20.100. Aldo/ket_red. 1 hit.
PANTHERPTHR11732. Aldo/ket_red. 1 hit.
PfamPF00248. Aldo_ket_red. 1 hit.
[Graphical view]
PIRSFPIRSF000097. AKR. 1 hit.
PRINTSPR00069. ALDKETRDTASE.
SUPFAMSSF51430. Aldo/ket_red. 1 hit.
PROSITEPS00798. ALDOKETO_REDUCTASE_1. 1 hit.
PS00062. ALDOKETO_REDUCTASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9X0A2_THEMA
AccessionPrimary (citable) accession number: Q9X0A2
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: December 14, 2011
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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