Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9X027

- TRMB_THEMA

UniProt

Q9X027 - TRMB_THEMA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA (guanine-N(7)-)-methyltransferase

Gene

trmB

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331S-adenosyl-L-methionineUniRule annotation
Binding sitei58 – 581S-adenosyl-L-methionineUniRule annotation
Binding sitei85 – 851S-adenosyl-L-methionineUniRule annotation
Binding sitei112 – 1121SubstrateUniRule annotation
Binding sitei144 – 1441SubstrateUniRule annotation

GO - Molecular functioni

  1. tRNA (guanine-N7-)-methyltransferase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

tRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

UniPathwayiUPA00989.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA (guanine-N(7)-)-methyltransferaseUniRule annotation (EC:2.1.1.33UniRule annotation)
Alternative name(s):
tRNA (guanine(46)-N(7))-methyltransferaseUniRule annotation
tRNA(m7G46)-methyltransferaseUniRule annotation
Gene namesi
Name:trmBUniRule annotation
Ordered Locus Names:TM_0925
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 313313tRNA (guanine-N(7)-)-methyltransferasePRO_0000171413Add
BLAST

Proteomic databases

PRIDEiQ9X027.

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0925.

Structurei

3D structure databases

ProteinModelPortaliQ9X027.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni177 – 1804Substrate bindingUniRule annotation

Sequence similaritiesi

Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0220.
InParanoidiQ9X027.
KOiK03439.
OMAiFPCPWPK.
OrthoDBiEOG6K6VBC.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_01057. tRNA_methyltr_TrmB.
InterProiIPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view]
PfamiPF02390. Methyltransf_4. 1 hit.
[Graphical view]
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00091. TIGR00091. 1 hit.
PROSITEiPS51625. SAM_MT_TRMB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X027-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVVTEYELKP QNFPRFPLDW SEIFGRKAKI VVEIGFGNGE FLAELARRHP
60 70 80 90 100
EKDFVGFEVS ITSFVKAQKK FKRYNLKNVR LVKVDARFGL RELFPDNSVE
110 120 130 140 150
KVYINFPCPW PKKRHESRRI TSYDFLQTLS AVLEMDGTVE FATDEEWYAR
160 170 180 190 200
EVLDTFESSE YFVVDVFEEN FKRDVETRYE RKWKSQGKKT FLIVARKVKN
210 220 230 240 250
GTVKRLMEGE NTMAHSVFEG NVTWEKLKEL EGKVFKDKNK IFVVKKVYRD
260 270 280 290 300
GDYLLKVIST DEGGFQQVYY LNLSGRDGKW VLKLDEGSDP YRTPALKWSL
310
RRIPEELTAQ GSP
Length:313
Mass (Da):36,770
Last modified:November 1, 1999 - v1
Checksum:i34EE4D3669AD2CF3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36006.1.
PIRiF72317.
RefSeqiNP_228733.1. NC_000853.1.
WP_004080637.1. NC_023151.1.
YP_007977277.1. NC_021214.1.
YP_008990105.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAAD36006; AAD36006; TM_0925.
GeneIDi18091859.
898599.
KEGGitma:TM0925.
PATRICi23936781. VBITheMar51294_0939.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36006.1 .
PIRi F72317.
RefSeqi NP_228733.1. NC_000853.1.
WP_004080637.1. NC_023151.1.
YP_007977277.1. NC_021214.1.
YP_008990105.1. NC_023151.1.

3D structure databases

ProteinModelPortali Q9X027.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 243274.TM0925.

Proteomic databases

PRIDEi Q9X027.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD36006 ; AAD36006 ; TM_0925 .
GeneIDi 18091859.
898599.
KEGGi tma:TM0925.
PATRICi 23936781. VBITheMar51294_0939.

Phylogenomic databases

eggNOGi COG0220.
InParanoidi Q9X027.
KOi K03439.
OMAi FPCPWPK.
OrthoDBi EOG6K6VBC.

Enzyme and pathway databases

UniPathwayi UPA00989 .

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
HAMAPi MF_01057. tRNA_methyltr_TrmB.
InterProi IPR029063. SAM-dependent_MTases-like.
IPR003358. tRNA_(Gua-N-7)_MeTrfase.
[Graphical view ]
Pfami PF02390. Methyltransf_4. 1 hit.
[Graphical view ]
SUPFAMi SSF53335. SSF53335. 1 hit.
TIGRFAMsi TIGR00091. TIGR00091. 1 hit.
PROSITEi PS51625. SAM_MT_TRMB. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Entry informationi

Entry nameiTRMB_THEMA
AccessioniPrimary (citable) accession number: Q9X027
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 2001
Last sequence update: November 1, 1999
Last modified: November 26, 2014
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3