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Protein
Submitted name:

Alcohol dehydrogenase, iron-containing

Gene

TM_0920

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei43 – 431NADPCombined sources
Binding sitei157 – 1571NADPCombined sources
Metal bindingi189 – 1891IronCombined sources
Metal bindingi189 – 1891ZincCombined sources
Metal bindingi193 – 1931Iron; via tele nitrogenCombined sources
Metal bindingi193 – 1931Zinc; via tele nitrogenCombined sources
Metal bindingi256 – 2561Iron; via tele nitrogenCombined sources
Metal bindingi256 – 2561Zinc; via tele nitrogenCombined sources
Metal bindingi270 – 2701Iron; via tele nitrogenCombined sources
Metal bindingi270 – 2701Zinc; via tele nitrogenCombined sources

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi38 – 392NADPCombined sources
Nucleotide bindingi68 – 692NADPCombined sources
Nucleotide bindingi96 – 1005NADPCombined sources
Nucleotide bindingi136 – 1372NADPCombined sources
Nucleotide bindingi142 – 1476NADPCombined sources
Nucleotide bindingi174 – 1774NADPCombined sources

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

IronCombined sources, Metal-bindingCombined sources, NADPCombined sources, Nucleotide-bindingCombined sources, ZincCombined sources

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-950-MONOMER.
BRENDAi1.1.1.202. 6331.

Names & Taxonomyi

Protein namesi
Submitted name:
Alcohol dehydrogenase, iron-containingImported
Gene namesi
Ordered Locus Names:TM_0920Imported
ORF Names:Tmari_0922Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000013901 Componenti: Chromosome
  • UP000008183 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0920.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1O2DX-ray1.30A/B2-359[»]
1VHDX-ray1.60A/B2-359[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini7 – 349343Fe-ADHInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105C0A. Bacteria.
COG1454. LUCA.
KOiK00001.
OMAiEKFAWIS.
OrthoDBiEOG686NDV.

Family and domain databases

InterProiIPR001670. ADH_Fe.
[Graphical view]
PfamiPF00465. Fe-ADH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9X022-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWEFYMPTDV FFGEKILEKR GNIIDLLGKR ALVVTGKSSS KKNGSLDDLK
60 70 80 90 100
KLLDETEISY EIFDEVEENP SFDNVMKAVE RYRNDSFDFV VGLGGGSPMD
110 120 130 140 150
FAKAVAVLLK EKDLSVEDLY DREKVKHWLP VVEIPTTAGT GSEVTPYSIL
160 170 180 190 200
TDPEGNKRGC TLMFPVYAFL DPRYTYSMSD ELTLSTGVDA LSHAVEGYLS
210 220 230 240 250
RKSTPPSDAL AIEAMKIIHR NLPKAIEGNR EARKKMFVAS CLAGMVIAQT
260 270 280 290 300
GTTLAHALGY PLTTEKGIKH GKATGMVLPF VMEVMKEEIP EKVDTVNHIF
310 320 330 340 350
GGSLLKFLKE LGLYEKVAVS SEELEKWVEK GSRAKHLKNT PGTFTPEKIR

NIYREALGV
Length:359
Mass (Da):39,943
Last modified:November 1, 1999 - v1
Checksum:i97871CB8584C70B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36001.1.
CP004077 Genomic DNA. Translation: AGL49847.1.
PIRiA72317.
RefSeqiNP_228728.1. NC_000853.1.
WP_004080642.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD36001; AAD36001; TM_0920.
AGL49847; AGL49847; Tmari_0922.
GeneIDi898594.
KEGGitma:TM0920.
tmi:THEMA_00035.
tmm:Tmari_0922.
tmw:THMA_0942.
PATRICi23936771. VBITheMar51294_0934.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD36001.1.
CP004077 Genomic DNA. Translation: AGL49847.1.
PIRiA72317.
RefSeqiNP_228728.1. NC_000853.1.
WP_004080642.1. NZ_CP011107.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1O2DX-ray1.30A/B2-359[»]
1VHDX-ray1.60A/B2-359[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0920.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD36001; AAD36001; TM_0920.
AGL49847; AGL49847; Tmari_0922.
GeneIDi898594.
KEGGitma:TM0920.
tmi:THEMA_00035.
tmm:Tmari_0922.
tmw:THMA_0942.
PATRICi23936771. VBITheMar51294_0934.

Phylogenomic databases

eggNOGiENOG4105C0A. Bacteria.
COG1454. LUCA.
KOiK00001.
OMAiEKFAWIS.
OrthoDBiEOG686NDV.

Enzyme and pathway databases

BioCyciTMAR243274:GC6P-950-MONOMER.
BRENDAi1.1.1.202. 6331.

Family and domain databases

InterProiIPR001670. ADH_Fe.
[Graphical view]
PfamiPF00465. Fe-ADH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported and MSB8Imported.
  2. "The genome organization of Thermotoga maritima reflects its lifestyle."
    Latif H., Lerman J.A., Portnoy V.A., Tarasova Y., Nagarajan H., Schrimpe-Rutledge A.C., Smith R.D., Adkins J.N., Lee D.H., Qiu Y., Zengler K.
    PLoS Genet. 9:E1003485-E1003485(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099Imported and MSB8Imported.

Entry informationi

Entry nameiQ9X022_THEMA
AccessioniPrimary (citable) accession number: Q9X022
Secondary accession number(s): G4FF70
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: March 16, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.