Q9WZZ7 (GLGA_THEMA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Glycogen synthase
EC=2.4.1.21

Alternative name(s):
Starch [bacterial glycogen] synthase

Gene names

Name:	glgA
Ordered Locus Names:	TM_0895

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP]

Taxonomic identifier

243274 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Thermotogae › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga › Thermotoga maritima

Protein attributes

Sequence length	486 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484
Catalytic activity	ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484
Sequence similarities	Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycogen biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular_function	starch synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 486	486	Glycogen synthase HAMAP-Rule MF_00484		PRO_0000188658
Sites
	Binding site	15	1	ADP-glucose By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q9WZZ7 [UniParc]. Last modified November 1, 1999. Version 1. Checksum: 99241A36AE2CF435	FASTA	486	55,456
	10 20 30 40 50 60 MKVVFVSYEV FPFAKVGGLA DVAGTLPKYL KKHGVDVTIV MPKHRIVEKN AEKFGYEIKK 70 80 90 100 110 120 VAESLSVSHV KTDQKFDIYE SVLPGSDVKT YFVANDYYFS AEDVYAGPDL GEQAIFFCAA 130 140 150 160 170 180 TLDLVKHLDL KPDIVHVNDW QTALIPVYLK TVYRDDPYFS RTATVLTIHN LGYQGVFDPK 190 200 210 220 230 240 YLSFAGLPDY VYTIDGLEFY GQLNFLKGGI VFSDVINTVS PTYAEEIQTE EYGEKLDGVL 250 260 270 280 290 300 RMRSKDLYGI LNGIDYELYN PATDRYIYVN YDVNRLELKW ENKVKLQEEL GLPVNKETAV 310 320 330 340 350 360 AGLISRLVPQ KGLDLLVDVM DYLTLFDLQI VVLGTGDEQY ENAFRKFQER YPDKVSANIK 370 380 390 400 410 420 FDVELAQKIY AGADIFLMPS RYEPCGLGQM FSMRYGTIPV VRYTGGLADT VKEYDPQSME 430 440 450 460 470 480 GTGFGFKKYD SAHLLKAVSK ALHFYYREKD HWRRIMTNAM NTDLSWDRSA KEYVDLYKKA LAKVGR

References

[1]

"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M. Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000512 Genomic DNA. Translation: AAD35976.1.
PIR	H72321.
RefSeq	NP_228703.1. NC_000853.1.
3D structure databases
ProteinModelPortal	Q9WZZ7.
ModBase	Search...
Protein-protein interaction databases
STRING	243274.TM0895.
Protein family/group databases
CAZy	GT5. Glycosyltransferase Family 5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD35976; AAD35976; TM_0895.
GeneID	898569.
KEGG	tma:TM0895.
PATRIC	23936721. VBITheMar51294_0909.
Phylogenomic databases
eggNOG	COG0297.
KO	K00703.
OMA	ERYPQNI.
ProtClustDB	CLSK875455.
Enzyme and pathway databases
UniPathway	UPA00164.
Family and domain databases
HAMAP	MF_00484. Glycogen_synth.
InterPro	IPR001296. Glyco_trans_1. IPR011835. Glycogen/starch_synth. IPR013534. Starch_synth_cat_dom. [Graphical view]
Pfam	PF08323. Glyco_transf_5. 1 hit. PF00534. Glycos_transf_1. 1 hit. [Graphical view]
TIGRFAMs	TIGR02095. glgA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGA_THEMA

Accession

Primary (citable) accession number: Q9WZZ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 16, 2001
Last sequence update:	November 1, 1999
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program