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Protein

Glycogen synthase

Gene

glgA

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:TM_0895
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
ProteomesiUP000008183: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 486486Glycogen synthasePRO_0000188658Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi243274.TM0895.

Structurei

3D structure databases

ProteinModelPortaliQ9WZZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
InParanoidiQ9WZZ7.
KOiK00703.
OMAiNLQINGM.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WZZ7-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MKVVFVSYEV FPFAKVGGLA DVAGTLPKYL KKHGVDVTIV MPKHRIVEKN
60 70 80 90 100
AEKFGYEIKK VAESLSVSHV KTDQKFDIYE SVLPGSDVKT YFVANDYYFS
110 120 130 140 150
AEDVYAGPDL GEQAIFFCAA TLDLVKHLDL KPDIVHVNDW QTALIPVYLK
160 170 180 190 200
TVYRDDPYFS RTATVLTIHN LGYQGVFDPK YLSFAGLPDY VYTIDGLEFY
210 220 230 240 250
GQLNFLKGGI VFSDVINTVS PTYAEEIQTE EYGEKLDGVL RMRSKDLYGI
260 270 280 290 300
LNGIDYELYN PATDRYIYVN YDVNRLELKW ENKVKLQEEL GLPVNKETAV
310 320 330 340 350
AGLISRLVPQ KGLDLLVDVM DYLTLFDLQI VVLGTGDEQY ENAFRKFQER
360 370 380 390 400
YPDKVSANIK FDVELAQKIY AGADIFLMPS RYEPCGLGQM FSMRYGTIPV
410 420 430 440 450
VRYTGGLADT VKEYDPQSME GTGFGFKKYD SAHLLKAVSK ALHFYYREKD
460 470 480
HWRRIMTNAM NTDLSWDRSA KEYVDLYKKA LAKVGR
Length:486
Mass (Da):55,456
Last modified:November 1, 1999 - v1
Checksum:i99241A36AE2CF435
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35976.1.
PIRiH72321.
RefSeqiNP_228703.1. NC_000853.1.
YP_007977247.1. NC_021214.1.
YP_008990135.1. NC_023151.1.

Genome annotation databases

EnsemblBacteriaiAAD35976; AAD35976; TM_0895.
GeneIDi18091888.
898569.
KEGGitma:TM0895.
tmi:THEMA_00160.
PATRICi23936721. VBITheMar51294_0909.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35976.1.
PIRiH72321.
RefSeqiNP_228703.1. NC_000853.1.
YP_007977247.1. NC_021214.1.
YP_008990135.1. NC_023151.1.

3D structure databases

ProteinModelPortaliQ9WZZ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi243274.TM0895.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAD35976; AAD35976; TM_0895.
GeneIDi18091888.
898569.
KEGGitma:TM0895.
tmi:THEMA_00160.
PATRICi23936721. VBITheMar51294_0909.

Phylogenomic databases

eggNOGiCOG0297.
InParanoidiQ9WZZ7.
KOiK00703.
OMAiNLQINGM.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Entry informationi

Entry nameiGLGA_THEMA
AccessioniPrimary (citable) accession number: Q9WZZ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: November 1, 1999
Last modified: February 4, 2015
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.