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Protein
Submitted name:

Sensor histidine kinase

Gene

TM_0853

Organism
Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei376ADPCombined sources1
Binding sitei380ATP analogCombined sources1
Binding sitei384ATP analogCombined sources1
Binding sitei411ADPCombined sources1
Binding sitei411ATP analogCombined sources1
Binding sitei430ATP analogCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi380 – 384ADPCombined sources5
Nucleotide bindingi430 – 434ADPCombined sources5
Nucleotide bindingi442 – 446ADPCombined sources5
Nucleotide bindingi442 – 446ATP analogCombined sources5

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Sensor histidine kinaseImported
Gene namesi
Ordered Locus Names:TM_0853Imported
OrganismiThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Imported
Taxonomic identifieri243274 [NCBI]
Taxonomic lineageiBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga
Proteomesi
  • UP000008183 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi330 ↔ 359Combined sources

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TM_0468Q9WYT94EBI-2464828,EBI-2464826

Protein-protein interaction databases

DIPiDIP-54544N.
IntActiQ9WZV7. 1 interactor.
STRINGi243274.TM0853.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2C2AX-ray1.90A232-489[»]
3DGEX-ray2.80A/B232-489[»]
4JASX-ray3.00A232-489[»]
4JAUX-ray2.70A232-489[»]
4JAVX-ray3.10A/B232-489[»]
4KP4X-ray3.00A/B284-462[»]
SMRiQ9WZV7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4105BZU. Bacteria.
ENOG410XNMH. LUCA.
KOiK02484.
OMAiMTATLAH.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
InterProiView protein in InterPro
IPR029016. GAF_dom-like.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
IPR003661. HisK_dim/P.
IPR004358. Sig_transdc_His_kin-like_C.
PfamiView protein in Pfam
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PRINTSiPR00344. BCTRLSENSOR.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SUPFAMiSSF47384. SSF47384. 1 hit.
SSF55874. SSF55874. 1 hit.
PROSITEiView protein in PROSITE
PS50109. HIS_KIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9WZV7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEEIKEQNNR LFLLLSIMIM EFSNAKTESD ILQGLLNLVR KVVDIKEVVL
60 70 80 90 100
VDENKRKIWG RDIDIKRFEE FIDWSIRQSN PVFVEDELGY VGIVPVVKQD
110 120 130 140 150
RMFGSLIVLL NHQPSMEETE IFKVLSFLSA VVLENIKLYR ELEETYNYVN
160 170 180 190 200
VILNGLPEGI FVYSNGEIKF QNEKFKEENF PDEVLRKAIS LSEEAISLRT
210 220 230 240 250
QRVGEVISGE EFFSITSIPL ILGSEVQALT IVENVTESKE LERLKRIDRM
260 270 280 290 300
KTEFIANISH ELRTPLTAIK AYAETIYNSL GELDLSTLKE FLEVIIDQSN
310 320 330 340 350
HLENLLNELL DFSRLERKSL QINREKVDLC DLVESAVNAI KEFASSHNVN
360 370 380 390 400
VLFESNVPCP VEAYIDPTRI RQVLLNLLNN GVKYSKKDAP DKYVKVILDE
410 420 430 440 450
KDGGVLIIVE DNGIGIPDHA KDRIFEQFYR VDSSLTYEVP GTGLGLAITK
460 470 480
EIVELHGGRI WVESEVGKGS RFFVWIPKDR AGEDNRQDN
Length:489
Mass (Da):56,017
Last modified:November 1, 1999 - v1
Checksum:i40F19F843A4EDDB4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000512 Genomic DNA. Translation: AAD35935.1.
PIRiF72324.
RefSeqiNP_228662.1. NC_000853.1.
WP_004080773.1. NZ_CP011107.1.

Genome annotation databases

EnsemblBacteriaiAAD35935; AAD35935; TM_0853.
AGL49780; AGL49780; Tmari_0855.
GeneIDi898525.
KEGGitma:TM0853.
tmi:THEMA_00370.
tmm:Tmari_0855.
tmw:THMA_0875.
PATRICifig|243274.17.peg.854.

Similar proteinsi

Entry informationi

Entry nameiQ9WZV7_THEMA
AccessioniPrimary (citable) accession number: Q9WZV7
Secondary accession number(s): G4FCX1
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: August 30, 2017
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported