NADH-dependent butanol dehydrogenase, putative

Preferred order of sections

Names and origin

Protein names

Submitted name:
NADH-dependent butanol dehydrogenase, putative EMBL AAD35902.1

Gene names

Ordered Locus Names:

TM_0820

Organism

Thermotoga maritima

Taxonomic identifier

2336 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	395 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Iron PDB 1VLJ Metal-binding PDB 1VLJ NADP PDB 1VLJ Nucleotide-binding PDB 1VLJ
Technical term	3D-structure PDB 1VLJ Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Regions

Nucleotide binding

40 – 42

3

NADP PDB 1VLJ

Nucleotide binding

99 – 103

5

NADP PDB 1VLJ

Nucleotide binding

148 – 150

3

NADP PDB 1VLJ

Nucleotide binding

180 – 183

4

NADP PDB 1VLJ

Sites

Metal binding

195

1

Iron PDB 1VLJ

Metal binding

199

1

Iron; via tele nitrogen PDB 1VLJ

Metal binding

268

1

Iron; via tele nitrogen PDB 1VLJ

Metal binding

282

1

Iron; via tele nitrogen PDB 1VLJ

Binding site

71

1

NADP; via carbonyl oxygen PDB 1VLJ

Binding site

139

1

NADP PDB 1VLJ

Binding site

143

1

NADP; via carbonyl oxygen PDB 1VLJ

Binding site

161

1

NADP PDB 1VLJ

Sequences

Sequence

Length

Mass (Da)

Tools

Q9WZS7 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 6053E21CD1DF374A
Show »

FASTA

395

43,355

        10         20         30         40         50         60 
MENFVFHNPT KIVFGRGTIP KIGEEIKNAG IRKVLFLYGG GSIKKNGVYD QVVDSLKKHG 

        70         80         90        100        110        120 
IEWVEVSGVK PNPVLSKVHE AVEVAKKEKV EAVLGVGGGS VVDSAKAVAA GALYEGDIWD 

       130        140        150        160        170        180 
AFIGKYQIEK ALPIFDVLTI SATGTEMNGN AVITNEKTKE KYGVSSKALY PKVSIIDPSV 

       190        200        210        220        230        240 
QFTLPKEQTV YGAVDAISHI LEYYFDGSSP EISNEIAEGT IRTIMKMTER LIEKPDDYEA 

       250        260        270        280        290        300 
RANLAWSATI ALNGTMAVGR RGGEWACHRI EHSLSALYDI AHGAGLAIVF PAWMKYVYRK 

       310        320        330        340        350        360 
NPAQFERFAK KIFGFEGEGE ELILKGIEAF KNWLKKVGAP VSLKDAGIPE EDIDKIVDNV 

       370        380        390 
MLLVEKNLKP KGASLGRIMV LEREDVREIL KLAAK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. Fraser C.M. Nature 399:323-329(1999) [PubMed: 10360571] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of NADH-dependent butanol dehydrogenase A (TM0820) from Thermotoga maritima at 1.78 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (JUL-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.78 ANGSTROMS) IN COMPLEX WITH IRON AND NADP.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD35902.1.

PIR

G72329.

RefSeq

NP_228629.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VLJ	X-ray	1.78	A/B	1-395	[»]

ProteinModelPortal

Q9WZS7.

SMR

Q9WZS7. Positions 1-395.

ModBase

Search...

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

898489.

GenomeReviews

Gene locus TM_0820 in contig AE000512_GR.

KEGG

tma:TM0820.

NMPDR

fig|243274.1.peg.813.

PATRIC

23936562. VBITheMar51294_0832.

TIGR

TM_0820.

Phylogenomic databases

HOGENOM

HBG742415.

OMA

VKPNPRL.

PhylomeDB

Q9WZS7.

ProtClustDB

CLSK875397.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_0820-MONOMER.

Family and domain databases

InterPro

IPR001670. ADH_Fe.
IPR018211. ADH_Fe_CS.
[Graphical view]

KO

K00100.

Pfam

PF00465. Fe-ADH. 1 hit.
[Graphical view]

PROSITE

PS00913. ADH_IRON_1. 1 hit.
PS00060. ADH_IRON_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q9WZS7_THEMA

Accession

Primary (citable) accession number: Q9WZS7

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)