Probable 2-phosphosulfolactate phosphatase - Thermotoga maritima

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Reviewed, UniProtKB/Swiss-Prot Q9WZQ4 (COMB_THEMA)

Last modified May 5, 2009. Version 48. History...

Clusters with 100%, 90%, 50% identity |

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
Probable 2-phosphosulfolactate phosphatase
EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	TM_0797

Organism

Thermotoga maritima [Complete proteome] [HAMAP]

Taxonomic identifier

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H₂O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

227

Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490

PRO_0000081477

Secondary structure

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227

Helix Strand Turn

Sequences

Sequence

Length

Mass (Da)

Tools

Q9WZQ4-1 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: ED32447E6140D9F8
Show »

227

24,857

        10         20         30         40         50         60 
MVDVVMAPCS PVECRTAVVI DVLRATSTIV TALSNGASGV IPVKTIEEAL EKKKEGVLIC 

        70         80         90        100        110        120 
GERNAQKPKG FNLGNSPLEY RKEKISGKTI VLTTTNGTQV IEKIRSEEII AASFLNLSAV 

       130        140        150        160        170        180 
VEYLKSKEDI LLVCAGTNGR FSLEDFLLAG AIVKRLKRND LGDGAHAAER YFESVENTRE 

       190        200        210        220 
EIKKHSSHAK RLISLGFEND IEFCTTEDLF KTVPALVNGV FILKEFP

References

[1]

"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S.

expand/collapse author list

Fraser C.M.
Nature 399:323-329(1999) [PubMed: 10360571] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.

Cross-references

Sequence databases

AE000512 Genomic DNA. Translation: AAD35879.1.

PIR

RefSeq

3D structure databases

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2YYV	X-ray	1.65	A/B	1-227	[»]
2YZO	X-ray	1.85	A/B	1-227	[»]

ModBase

Genome annotation databases

GeneID

GenomeReviews

Gene locus TM_0797 in contig AE000512_GR.

KEGG

NMPDR

fig|243274.1.peg.790.

TIGR

Phylogenomic databases

HOGENOM

OMA

Q9WZQ4. DFICSGY.

Enzyme and pathway databases

BioCyc

TMAR243274:TM_0797-MON.

BRENDA

3.1.3.71. 16699.

Family and domain databases

HAMAP

MF_00490.
[Tree]

InterPro

IPR005238. 2-PSlactate_phosphatase.
[Graphical view]

Gene3D

G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.

Pfam

PF04029. 2-ph_phosp. 1 hit.
[Graphical view]

ProtoNet

Entry information

Entry name

COMB_THEMA

Accession

Primary (citable) accession number: Q9WZQ4

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	November 1, 1999
Last modified:	May 5, 2009
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents