Flavodoxin/nitric oxide synthase - Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Flavodoxin/nitric oxide synthase EMBL EHA61303.1

Gene names

Ordered Locus Names:	TM_0755
ORF Names:	ThemaDRAFT_0546 EMBL EHA61303.1

Organism

Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099) [Reference proteome] [HAMAP]

Taxonomic identifier

243274 [NCBI]

Taxonomic lineage

Bacteria › Thermotogae › Thermotogales › Thermotogaceae › Thermotoga ›

Protein attributes

Sequence length	398 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Biological process	Electron transport SAAS SAAS008254 Transport
Ligand	Iron PDB 1VME Metal-binding PDB 1VME
Technical term	3D-structure PDB 1VME PDB 4DIK PDB 4DIL Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	FMN binding Inferred from electronic annotation. Source: InterPro electron carrier activity Inferred from electronic annotation. Source: InterPro hydrolase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

85

1

Iron oxide (2Fe-O) PDB 1VME

Metal binding

87

1

Iron oxide (2Fe-O) PDB 1VME

Metal binding

89

1

Iron oxide (2Fe-O) PDB 1VME

Metal binding

90

1

Iron oxide (2Fe-O) PDB 1VME

Metal binding

151

1

Iron oxide (2Fe-O) PDB 1VME

Metal binding

168

1

Iron oxide (2Fe-O) PDB 1VME

Metal binding

228

1

Iron oxide (2Fe-O) PDB 1VME

Sequences

Sequence

Length

Mass (Da)

Tools

Q9WZL4 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 78688C3E78771719
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FASTA

398

45,271

        10         20         30         40         50         60 
MPKIWTERIF DDPEIYVLRI DDDRIRYFEA VWEIPEGISY NAYLVKLNGA NVLIDGWKGN 

        70         80         90        100        110        120 
YAKEFIDALS KIVDPKEITH IIVNHTEPDH SGSLPATLKT IGHDVEIIAS NFGKRLLEGF 

       130        140        150        160        170        180 
YGIKDVTVVK DGEEREIGGK KFKFVMTPWL HWPDTMVTYL DGILFSCDVG GGYLLPEILD 

       190        200        210        220        230        240 
DSNESVVERY LPHVTKYIVT VIGHYKNYIL EGAEKLSSLK IKALLPGHGL IWKKDPQRLL 

       250        260        270        280        290        300 
NHYVSVAKGD PKKGKVTVIY DSMYGFVENV MKKAIDSLKE KGFTPVVYKF SDEERPAISE 

       310        320        330        340        350        360 
ILKDIPDSEA LIFGVSTYEA EIHPLMRFTL LEIIDKANYE KPVLVFGVHG WAPSAERTAG 

       370        380        390 
ELLKETKFRI LSFTEIKGSN MDERKIEEAI SLLKKELE

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima." Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. Fraser C.M. Nature 399:323-329(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]	"Crystal structure of Flavoprotein (TM0755) from Thermotoga maritima at 1.80 A resolution." Joint Center for Structural Genomics (JCSG) Submitted (SEP-2004) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH IRON OXIDE (2FE-O).
[3]	"The draft genome of Thermotoga maritima MSB8." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Han J., Lapidus A., Cheng J.-F., Goodwin L., Pitluck S., Peters L., Land M.L., Hauser L., Boucher N., Noll K., Woyke T. Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: MSB8 EMBL EHA61303.1.
[4]	"Histidine ligand variants of a flavo-diiron protein: effects on structure and activities." Fang H., Caranto J.D., Mendoza R., Taylor A.B., Hart P.J., Kurtz D.M. J. Biol. Inorg. Chem. 17:1231-1239(2012) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.75 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE000512 Genomic DNA. Translation: AAD35837.1.
AGIJ01000001 Genomic DNA. Translation: EHA61303.1.

PIR

A72338.

RefSeq

NP_228564.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1VME	X-ray	1.80	A/B	1-398	[»]
4DIK	X-ray	1.75	A/B	1-398	[»]
4DIL	X-ray	2.00	A/B	1-398	[»]

SMR

Q9WZL4. Positions 1-398.

ModBase

Search...

Protein-protein interaction databases

STRING

243274.TM0755.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAD35837; AAD35837; TM_0755.
EHA61303; EHA61303; ThemaDRAFT_0546.

GeneID

898423.

KEGG

tma:TM0755.

PATRIC

23936432. VBITheMar51294_0768.

Phylogenomic databases

OMA

FRILSFT.

ProtClustDB

CLSK865278.

Family and domain databases

InterPro

IPR001279. Beta-lactamas-like.
IPR008254. Flavodoxin/NO_synth.
IPR016440. Rubredoxin-O_OxRdtase.
[Graphical view]

Pfam

PF00258. Flavodoxin_1. 1 hit.
PF00753. Lactamase_B. 1 hit.
[Graphical view]

PIRSF

PIRSF005243. ROO. 1 hit.

SMART

SM00849. Lactamase_B. 1 hit.
[Graphical view]

PROSITE

PS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q9WZL4.

Entry information

Entry name

Q9WZL4_THEMA

Accession

Primary (citable) accession number: Q9WZL4
Secondary accession number(s): G4FD68

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1999
Last sequence update:	November 1, 1999
Last modified:	May 1, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)