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Q9WZD3 (Q9WZD3_THEMA) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cysteine synthase RuleBase RU003985

EC=2.5.1.47 RuleBase RU003985
Gene names
Ordered Locus Names:TM_0665
OrganismThermotoga maritima
Taxonomic identifier2336 [NCBI]
Taxonomic lineageBacteriaThermotogaeThermotogalesThermotogaceaeThermotoga

Protein attributes

Sequence length291 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985

Sequence similarities

Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Sequences

Sequence LengthMass (Da)Tools
Q9WZD3 [UniParc].

Last modified November 1, 1999. Version 1.
Checksum: 2089B88B573411EE

FASTA29131,130
        10         20         30         40         50         60 
MMERLIGSTP IVRLDSIDSR IFLKLEKNNP GGSVKDRPAL FMILDAEKRG LLKNGIVEPT 

        70         80         90        100        110        120 
SGNMGIAIAM IGAKRGHRVI LTMPETMSVE RRKVLKMLGA ELVLTPGELG MKGAVEKALE 

       130        140        150        160        170        180 
ISRETGAHML NQFENPYNVY SHQFTTGPEI LKQMDYQIDA FVAGVGTGGT ISGVGRVLKG 

       190        200        210        220        230        240 
FFGNGVKIVA VEPAKSPVLS GGQPGKHAIQ GIGAGFVPKI LDRSVIDEVI TVEDEEAYEM 

       250        260        270        280        290 
ARYLAKKEGL LVGISSGANV AAALKVAQKL GPDARVVTVA PDHAERYLSI L 

« Hide

References

« Hide 'large scale' references
[1]"Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima."
Nelson K.E., Clayton R.A., Gill S.R., Gwinn M.L., Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Nelson W.C., Ketchum K.A., McDonald L.A., Utterback T.R., Malek J.A., Linher K.D., Garrett M.M., Stewart A.M., Cotton M.D., Pratt M.S. expand/collapse author list , Phillips C.A., Richardson D.L., Heidelberg J.F., Sutton G.G., Fleischmann R.D., Eisen J.A., White O., Salzberg S.L., Smith H.O., Venter J.C., Fraser C.M.
Nature 399:323-329(1999) [PubMed: 10360571] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 43589 / MSB8 / DSM 3109 / JCM 10099.
[2]"Crystal structure of O-acetylserine sulfhydrylase (TM0665) from Thermotoga maritima at 1.8 A resolution."
Heine A., Canaves J.M., von Delft F., Brinen L.S., Dai X., Deacon A.M., Elsliger M.A., Eshaghi S., Floyd R., Godzik A., Grittini C., Grzechnik S.K., Guda C., Jaroszewski L., Karlak C., Klock H.E., Koesema E., Kovarik J.S. expand/collapse author list , Kreusch A., Kuhn P., Lesley S.A., McMullan D., McPhillips T.M., Miller M.A., Miller M.D., Morse A., Moy K., Ouyang J., Page R., Robb A., Rodrigues K., Schwarzenbacher R., Selby T.L., Spraggon G., Stevens R.C., van den Bedem H., Velasquez J., Vincent J., Wang X., West B., Wolf G., Hodgson K.O., Wooley J., Wilson I.A.
Proteins 56:387-391(2004) [PubMed: 15211522] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS).
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000512 Genomic DNA. Translation: AAD35748.1.
PIRF72349.
RefSeqNP_228474.1. NC_000853.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1O58X-ray1.80A/B/C/D1-291[»]
ProteinModelPortalQ9WZD3.
SMRQ9WZD3. Positions 1-291.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID897780.
GenomeReviewsGene locus TM_0665 in contig AE000512_GR.
KEGGtma:TM0665.
NMPDRfig|243274.1.peg.658.
PATRIC23936244. VBITheMar51294_0675.
TIGRTM_0665.

Phylogenomic databases

HOGENOMHBG748215.
OMARRNMIKA.
PhylomeDBQ9WZD3.
ProtClustDBCLSK875280.

Enzyme and pathway databases

BioCycTMAR243274:TM_0665-MONOMER.

Family and domain databases

InterProIPR001216. Cys_synth_BS.
IPR005856. Cys_synthKM.
IPR005859. CysK.
IPR001926. PyrdxlP-dep_enz_bsu.
[Graphical view]
KOK01738.
PfamPF00291. PALP. 1 hit.
[Graphical view]
SUPFAMSSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMsTIGR01139. CysK. 1 hit.
TIGR01136. CysKM. 1 hit.
PROSITEPS00901. CYS_SYNTHASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ9WZD3_THEMA
AccessionPrimary (citable) accession number: Q9WZD3
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1999
Last sequence update: November 1, 1999
Last modified: December 14, 2011
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)